Results 171 to 180 of about 21,740 (289)

Evaluation of the standard battery of in vitro genotoxicity tests to predict in vivo genotoxicity through mathematical modeling: A report from the 8th International Workshop on Genotoxicity Testing

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
Abstract In human health risk assessment of chemicals and pharmaceuticals, identification of genotoxicity hazard usually starts with a standard battery of in vitro genotoxicity tests, which is needed to cover all genotoxicity endpoints. The individual tests included in the battery are not designed to pick up all endpoints.
Mirjam Luijten   +15 more
wiley   +1 more source

Consensus findings of an International Workshops on Genotoxicity Testing workshop on using transcriptomic biomarkers to predict genotoxicity

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
Abstract Gene expression biomarkers have the potential to identify genotoxic and non‐genotoxic carcinogens, providing opportunities for integrated testing and reducing animal use. In August 2022, an International Workshops on Genotoxicity Testing (IWGT) workshop was held to critically review current methods to identify genotoxicants using ...
Roland Froetschl   +14 more
wiley   +1 more source

Developing a Novel Agrochemical-Based MOF: A Multifunctional Platform with Herbicidal and Antibacterial Activities. [PDF]

open access: yesACS Appl Mater Interfaces
Contreras M   +4 more
europepmc   +1 more source

Critical Evaluation of Methods for the Identification of Aneugens

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
ABSTRACT The genotoxic potential of chemicals must be evaluated in regulatory safety assessment settings, including but not limited to, the development of new pharmaceuticals, industrial chemicals, food and cosmetic ingredients, and agrochemicals. Initial assessment of the chromosome‐damaging potential of chemicals is often conducted in mammalian cells
Xiaowen Sun   +8 more
wiley   +1 more source

From waste to resource: Garlic peel‐derived proteases (Allium sativum) for nematode control

open access: yesEnvironmental Progress &Sustainable Energy, EarlyView.
Abstract This study aimed to prepare a protease‐rich extract from garlic peel (Allium sativum) and evaluate its nematicidal potential. The garlic peel was crushed, suspended in distilled water, and the obtained extract was subjected to filtration, centrifugation, and dialysis to concentrate the proteases. The nematicidal activity was tested in vitro on
Cecilia Baldoino Ferreira   +8 more
wiley   +1 more source

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