Results 91 to 100 of about 80,641 (259)

Longitudinal blood pressure trajectories before 20 weeks of gestation and adverse outcomes in women with chronic hypertension

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To explore the different patterns in early‐pregnancy mean arterial pressure (MAP) trajectories before 20 weeks of gestation in pregnant women with chronic hypertension, and whether it can stratify risk for adverse perinatal outcomes.
Haoyu Zuo, Yike Yang, Huanyu You, Chunjie Gong, Yan Wang   +4 more
wiley   +1 more source

STRUCTURAL INSIGHT INTO THE BINDING OF ACETOHYDROXAMIC ACID TO CONSERVED RESIDUES OF APO AND HOLO UREASE IN CLINICAL ISOLATES OF KLEBSIELLA SPP.

Brazilian Journal of Infectious Diseases
Introduction: Klebsiella is a clinically relevant bacterial genus associated with multidrug resistance. Urease is a virulence factor and a potential target for inhibitor-based interventions (Shafik et al., 2023).
João Pedro Vasques da Conceição, Fabio Faria da Mota   +1 more
doaj   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Synergistic inhibition of ureolytic activity and growth of Klebsiella pneumoniae in vitro suggests cobinding of fluoride and acetohydroxamic acid at the urease active site and provides a novel strategy to combat ureolytic bacteria

Heliyon
The ability of ureolytic bacteria to break down stable urea to alkaline ammonia leads to several environmental and health challenges. Ureolytic bacteria such as Helicobacter pylori, Klebsiella pneumoniae, and Proteus mirabilis can become pathogenic and ...
Simon Svane, Mie C. Lyngsie, Janne K. Klitgaard, Henrik Karring   +3 more
doaj   +1 more source

Genetic Biomarkers in the Risk Assessment of Sudden Cardiac Events: A Personalized Approach

iNew Medicine, EarlyView.
Genetic insights into the risk assessment of sudden cardiac events. ABSTRACT Sudden cardiac events are the leading cause of death worldwide. Conventional risk stratification methods, which largely depend on clinical history, imaging, and electrocardiography, are usually inadequate for identifying high‐risk individuals, especially those without visible ...
Shrikant Verma, Sushma Verma, Mohammad Abbas, Tabrez Faruqui, Bashir Ahmad Mir, Farzana Mahdi   +5 more
wiley   +1 more source

Guideline Concordance of ChatGPT‐Generated Responses on Antibiotic Prophylaxis in Endodontics

Journal of Dental Education, EarlyView.
ABSTRACT Antibiotic prophylaxis decision‐making in endodontics represents a core competency in dental education, requiring the integration of systemic risk assessment, guideline interpretation, and antimicrobial stewardship principles. Although artificial intelligence (AI) tools such as ChatGPT are increasingly accessed by students and clinicians for ...
Flavia Moura Medina Diniz, Pedro Rossato Lourenço, Antonio Miranda da Cruz‐Filho, Fabiane Carneiro Lopes‐Olhê, Jardel Francisco Mazzi‐Chaves, Laís Valencise Magri   +5 more
wiley   +1 more source

The impact of private equity acquisition of US hospitals on patient outcomes: A systematic review

Journal of Hospital Medicine, EarlyView.
Abstract Background Private equity (PE) firms are increasingly acquiring US hospitals. While PE ownership may infuse capital and managerial expertise, restructuring by organizations with limited patient‐care experience raises safety concerns. The effect of PE ownership on hospital outcomes remains poorly defined.
Angad S. Sidhu, Nikola S. Vuckovic, Salil Gupta, Christopher M. Garcia, Manav B. Patel, Cristiane M. Ueno   +5 more
wiley   +1 more source

Investigation of the hemostatic efficacy and acute histopathological effects of herbal algan hemostatic agent in partial nephrectomy model in rats

Surgical and Experimental Pathology
Background Uncontrolled bleeding during partial nephrectomy poses a significant surgical challenge. This study evaluates the hemostatic efficacy and acute histopathological effects of Algan Hemostatic Agent (AHA), a novel plant-based agent, in a rat ...
Dila Şener Akçora, Birgün Özçolak, Kağan Gökçe, Kevser Ceyda Çınar, Ahmet Midi   +4 more
doaj   +1 more source

Association Between MRI‐Derived Right‐to‐Left Ventricular Volume Ratio and Regional Left Ventricular Myocardial Dysfunction in Patients With Pulmonary Arterial Hypertension

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Right ventricular (RV) to left ventricular (LV) end‐diastolic volume ratio (RV/LV) is a validated marker of RV dilation in pulmonary arterial hypertension (PAH), yet its impact on LV myocardial function and the underlying mediating pathway is incompletely characterized.
Han Fang, Yuan Li, Jin Wang, Wei‐Feng Yan, Ke Shi, Shi‐Qin Yu, Xue Li, Wen‐Rong Li, Jia‐Ke Li, Jing‐Yi Guo, Li Jiang, Zhi‐Gang Yang   +11 more
wiley   +1 more source

Probiotics and intestinal permeability in adults with metabolic dysfunction‐associated steatohepatitis: A secondary analysis of a randomized clinical trial

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background Metabolic dysfunction‐associated steatohepatitis (MASH) is associated with altered intestinal permeability, allowing microbial products to translocate to the liver via the enterohepatic circulation and contributes to disease progression. The aim of our study was to evaluate the association between probiotic supplementation and serum
Bruna Concheski de Moura, Samanta Catherine Ferreira, Amanda Souza Silva‐Sperb, Helena Abadie Moraes, Larisse Longo, Carolina Uribe‐Cruz, Matheus Truccolo Michalczuk, Themis Reverbel da Silveira, Carlos Thadeu Schmidt Cerski, Mário Reis Álvares da Silva, Valesca Dall'Alba   +10 more
wiley   +1 more source