Results 31 to 40 of about 80,641 (259)

Development of a Disease Activity Index for the Assessment of VEXAS Syndrome (VEXAS‐DAI)

open access: yesArthritis Care &Research, EarlyView.
Objective Vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic syndrome (VEXAS) syndrome is characterized by a complex spectrum of inflammatory and hematologic manifestations. Clinical research to identify effective therapies is urgently needed but is hindered by the lack of validated outcome measures.
Kevin Byram   +25 more
wiley   +1 more source

Microvascular Damage Is Associated With Carotid Wall Structural Changes in Systemic Sclerosis: A Capillaroscopy and Ultrasound‐Based Observational Study

open access: yesArthritis Care &Research, EarlyView.
Objective Systemic sclerosis (SSc) is characterized by cardiovascular risk excess not fully explained by traditional factors. Whether the severity of microvascular damage correlates with structural subclinical atherosclerosis remains unclear. We investigated the relationship between nailfold videocapillaroscopy (NVC) abnormalities and carotid ...
Eugenio Capparelli   +13 more
wiley   +1 more source

Aha! under pressure: The Aha! experience is not constrained by cognitive load

open access: yesCognition, 2022
The Aha! moment- the sudden insight sometimes reached when solving a vexing problem- entails a different problem-solving experience than solution retrieval reached by an analytical, multistep strategy (i.e., non-insight). To date, the (un)conscious nature of insight remains debated. We addressed this by studying insight under cognitive load. If insight
Stuyck, Hans   +2 more
openaire   +4 more sources

Optical Detection of Cellular Signals at Material Interfaces

open access: yesAdvanced Healthcare Materials, EarlyView.
Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren   +5 more
wiley   +1 more source

Computed Tomography‐ and Photoacoustic Imaging‐Active Bioresorbable Electrospun Bismuth Nanoparticle‐Infused Small‐Diameter Vascular Grafts

open access: yesAdvanced Healthcare Materials, EarlyView.
A polymeric graft loaded with radiopaque bismuth nanoparticles is expected to undergo gradual polymer resorption and nanoparticle release. This design enables noninvasive, multimodal monitoring of device integrity, patency, and degradation using computed tomography alongside ultrasound and photoacoustic imaging over 12 weeks.
Allan John R. Barcena   +13 more
wiley   +1 more source

Microfluidic Droplet Plate Preserving Single Human Induced Pluripotent Stem Cell‐Derived Cardiomyocytes Morphology and Function

open access: yesAdvanced Materials Technologies, EarlyView.
We introduce a novel method combining microfluidics, optogenetics, and human induced pluripotent stem cell (iPSC) technology to encapsulate single iPSC‐derived cardiomyocytes (iPSC‐CMs) in an optimal environment for functional characterization. This method enables direct genotype‐phenotype correlation for genetic studies and high‐throughput screening ...
Xiao‐Ting Wang   +7 more
wiley   +1 more source

Acquired Hemophilia A: A Permanent Challenge for All Physicians

open access: yesMedicines, 2022
Acquired hemophilia A (AHA) is a rare disease with a prevalence in Europe of 1.5 per million. This diagnosis is significantly delayed in about one-third of all cases, leading to deferred treatment.
Knut M. Nowak   +3 more
doaj   +1 more source

Ultrasound‐Activated Piezoelectric Neuroimmune Hydrogel Orchestrates Neurogenesis‐Macrophage Crosstalk in Diabetic Wound Healing

open access: yesAdvanced Science, EarlyView.
In this work, we design an ultrasound‐activated piezoelectric hydrogel platform (AOEF@AP5+US) that reprograms neurogenesis‐macrophage crosstalk as an integrated strategy to overcome the intertwined barriers of chronic inflammation, peripheral neuropathy, and impaired regeneration in diabetic wounds.
Kai Wang   +13 more
wiley   +1 more source

Presentación: La Historia continúa

open access: yesHistoria Actual On-Line, 2008
Por fortuna para quienes humildemente cultivamos este conocimiento, la Historia continúa. Las utopías finalistas que hace sólo una década inundaron el mercado de la letra impresa han sido borradas de un plumazo por la tozudez de los hechos.
Julio Perez Serrano
doaj  

An Outbreak of Hepatitis A among Young Adult Men in Cyprus

open access: yesPathogens, 2020
Background: Outbreaks of acute hepatitis A (AHA) have recently been reported in Europe among men who have sex with men (MSM). The aim of this work was to evaluate, for the first time, trends in the reported cases of AHA in Cyprus over the last seven ...
Panagiotis Dimitriou   +6 more
doaj   +1 more source

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