Results 141 to 150 of about 6,599 (254)

Gut microbiota dysbiosis in the inflammatory pathogenesis of diabetic retinopathy

VIEW, EarlyView.
This graphical abstract illustrates how gut dysbiosis drives diabetic retinopathy through the gut‐retina axis, a process unfolding in three interconnected stages. First, in the gut, a decrease in beneficial bacteria and an increase in pro‐inflammatory taxa compromise the intestinal barrier, causing a “leaky gut” that allows LPS to translocate into the ...
Junyan Hu, Jingxiang Zhong
wiley   +1 more source

AHR Gene [PDF]

, 2020
openaire   +1 more source

Identification and Validation of Biomarkers in Chronic Rhinosinusitis With Nasal Polyps and Study of Their Associated Mechanisms

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Cell senescence (CS) and lipid metabolism (LM) disorders have been reported in chronic rhinosinusitis with nasal polyps (CRSwNP). However, the mechanism is still unclear. Methods Data were obtained from public databases; differential expression analysis and machine learning were performed to identify biomarkers and to understand the
Hui‐Yi Deng, Hui‐Jun Qiu, Ming‐Rui Pan, Qin‐Tai Yang   +3 more
wiley   +1 more source

Caution in handling switchers in pharmacoepidemiologic studies estimating treatment effects: the example of dipeptidyl peptidase-4 inhibitors and inflammatory bowel disease. [PDF]

Am J Epidemiol
Wang T, Wang J, Song Z, Miller E, Pate V, Her Q, Yang J, Charlier SHR, Egger P, Barnes EL, Buse JB, Becker C, Sandler RS, Meier C, Jick S, Stürmer T.   +15 more
europepmc   +1 more source

Neuroendocrine Carcinoma of the Head and Neck: A Two‐Decade Institutional Experience

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives Primary neuroendocrine carcinoma (NEC) of the head and neck is rare (< 1% of cases) and aggressive, with poorly defined management strategies. This study evaluated clinical characteristics, treatment patterns, and survival outcomes in a single‐institution cohort, identifying factors associated with improved survival.
Micah K. Harris, Katie M. Carlson, Nathan Lu, Anthony Tang, Matthew E. Spector, Joshua D. Smith, Jessica H. Maxwell, Kevin J. Contrera, Seungwon Kim, Steven B. Chinn, Angela Mazul, Shaum S. Sridharan   +11 more
wiley   +1 more source

Gastrointestinal Surgery Status and the Risks of Ischemic Stroke and Safety Outcomes With Direct Oral Anticoagulants Versus Warfarin in Atrial Fibrillation: A Nationwide Population-Based Cohort Study. [PDF]

J Stroke
Ha J, Yang W, Kim MS, Lee EJ, Chung M, Yang B, Jang H, Kim JM, Jung KH, Lee SH.   +9 more
europepmc   +1 more source

A high‐energy X‐ray beamline for materials science research at SPring‐8: BL15XU

Journal of Synchrotron Radiation, EarlyView.
The Japanese synchrotron facility SPring‐8 has recently relaunched BL15XU as a high‐energy X‐ray beamline for materials science research. A comprehensive description of the technical details and science cases is presented.The high‐energy X‐ray beamline BL15XU is designed to drive advancements in materials science and high‐pressure research by ...
Hiroyuki Ohsumi, Yuji Higo, Yujiro Hayashi, Jaemyung Kim, Noriyoshi Tsujino, Sho Kakizawa, Tetsuo Irifune, Tomohiro Ohuchi, Yoshio Kono, Hirokatsu Yumoto, Takahisa Koyama, Hiroshi Yamazaki, Yasunori Senba, Haruhiko Ohashi, Hidekazu Takano, Michihiro Sugahara, Taito Osaka, Makina Yabashi   +17 more
wiley   +1 more source

Younger age and prior graft failure are associated with increased risk of ACL reinjury: Graft survival and contralateral ACL outcomes at a median 10.6-year follow-up after primary hamstring autograft reconstruction. [PDF]

J Exp Orthop
Perico DA, Lievano JR, González S, Arango GC, Zayed G, Alviar KM.   +5 more
europepmc   +1 more source

Real‐World Effectiveness, Treatment Course, and Safety of Tapinarof Cream 1% for Atopic Dermatitis and Plaque Psoriasis in Japan

The Journal of Dermatology, EarlyView.
ABSTRACT Background Tapinarof cream 1%, a non‐steroidal topical aryl hydrocarbon receptor‐modulating agent, is approved in Japan for atopic dermatitis (AD) and plaque psoriasis. Real‐world data on longitudinal outcomes, treatment continuation, interruption and restart, and adverse‐event timing are limited. Methods This single‐center retrospective study
Kanade Iino, Saori Takamura, Tomoo Fukuda   +2 more
wiley   +1 more source

Patient characteristics associated with clinically coded long COVID: an OpenSAFELY study using electronic health records. [PDF]

BJGP Open
Wei Y, Horne EM, Knight R, Cezard G, Walker AJ, Fisher L, Denholm R, Taylor K, Walker V, Riley S, Williams DM, Willans R, Davy S, Bacon S, Goldacre B, Mehrkar A, Denaxas S, Greaves F, Silverwood RJ, Sheikh A, Chaturvedi N, Wood AM, Macleod J, Steves C, Sterne J, UK COVID-19 Longitudinal Health and Wellbeing National Core Study and CONVALESCENCE study.   +25 more
europepmc   +1 more source