Results 141 to 150 of about 8,340 (295)

The role of the AHR in host–pathogen interactions

Nature Reviews Immunology
Host-microorganism encounters take place in many different ways and with different types of outcomes. Three major types of microorganisms need to be distinguished: (1) pathogens that cause harm to the host and must be controlled; (2) environmental microorganisms that can be ignored but must be controlled at higher abundance; and (3) symbiotic ...
Palmira Barreira-Silva, Yilong Lian, Stefan H. E. Kaufmann, Pedro Moura-Alves   +3 more
openaire   +5 more sources

Microbial metabolite indole‐3‐propionic acid preserves astrocytic mitochondrial mitofusin 2 to limit neuroinflammation after traumatic brain injury

Interdisciplinary Medicine, EarlyView.
Following traumatic brain injury, indole‐3‐propionic acid (IPA) directly targets the aryl hydrocarbon receptor on astrocytes in the peri‐lesional cortex; this suppresses interferon regulatory factor 1‐driven transcription of the E3 ubiquitin ligase RFFL (ring finger and FYVE‐like domain containing E3 ubiquitin protein ligase).
Ziwen Zhang, Kai Wang, Liangbo Wang, Wencong Li, Hao Guo, Meng Xu, Tinghao Wang, Jiahui Ren, Ting Zhu, Jiahui Wang, Wenxing Cui, Jinpeng Zhou, Yang Tian, Liying Han, Chengxuan Guo, Shuoyao Ma, Qiang Wang, Zhihong Li, Yaning Cai, Jingyu Dong, Xun Wu, Haixiao Liu, Yan Qu   +22 more
wiley   +1 more source

Half a Century of Per‐ and Polyfluoroalkyl Substances in Northern Gannet Eggs: Impact of Regulations

Journal of Applied Toxicology, EarlyView.
ABSTRACT Per‐ and polyfluoroalkyl substances (PFAS), known as “forever chemicals”, are persistent organic pollutants that have been widely used in the industry across the globe for many decades. Their chemical stability, bioaccumulation, and toxicity pose major environmental and health risks. This study examines temporal trends in the concentrations of
Anaïs Fournier, Anaïs Kerric, Raphaël A. Lavoie   +2 more
wiley   +1 more source

Mode‐of‐Action and Human Relevance Assessment for Diisononyl Phthalate‐Induced Liver Tumors in Rodents

Journal of Applied Toxicology, EarlyView.
ABSTRACT Diisononyl phthalate (DINP) is a high molecular weight phthalate and high production volume chemical. DINP's carcinogenic potential has been investigated in four rodent bioassays, with liver tumors observed in three of the studies. Authoritative assessments have hypothesized that DINP acts through the peroxisome proliferator‐activated receptor
Amanda N. Buerger, Melissa M. Heintz, Laurie C. Haws, Chad M. Thompson   +3 more
wiley   +1 more source

Implementation of Automatic Hotel Reservation System (AHRS) on J2EE Framework [PDF]

, 2009
Nowadays, hotels are in the large-scale distributed environments where each site is completely autonomous and offers services to its customer through transparent external communication.
Soe, Khin Mar, Khaing, Moh Moh
core  

Maternal influenza vaccination during pregnancy and risk of autism spectrum disorder in the offspring

JCPP Advances, EarlyView.
Abstract Background Vaccination has been proposed as a potential risk factor for autism spectrum disorder (ASD), contributing to public hesitancy and mistrust toward immunization. Influenza vaccination during pregnancy is considered safe and effective in preventing serious maternal complications and adverse birth outcomes associated with influenza ...
Shahar Neeman, Maor Hemo, Gal Meiri, Dorit Shmueli, Idan Menashe   +4 more
wiley   +1 more source

Sex differences in 5‐year incidence and prevalence of physical illnesses following early childhood autism diagnosis

JCPP Advances, EarlyView.
Abstract Background Sex differences in the clinical presentation of autism are established, but evidence on early‐life co‐occurring physical illnesses in early‐diagnosed autistic individuals is scarce. This nationwide cohort study examined sex‐stratified incidence of physical illnesses within 5 years after autism spectrum disorder (ASD) diagnosis in ...
Yu‐Chieh Chuang, Yu‐Jui Huang, Meng‐Chuan Lai, Wen‐Yin Chen, Chun‐Hung Pan, Sheng‐Siang Su, Chian‐Jue Kuo   +6 more
wiley   +1 more source

Bowel ultrasound scan in the management of pediatric moderate ulcerative colitis: The applicability of international bowel ultrasound segmental activity score

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives To evaluate bowel ultrasound (BUS) findings and the diagnostic and prognostic performance of international bowel ultrasound segmental activity score (IBUS‐SAS) in children with moderate ulcerative colitis (UC), including its accuracy for assessing endoscopic activity and predicting clinical remission and colectomy within 12 months ...
Martina Di Benedetto, Luca Scarallo, Camilla Pannacci, Sara Renzo, Monica Paci, Sara Naldini, Jacopo Barp, Laura Tasciotti, Paolo Lionetti   +8 more
wiley   +1 more source

Polícia e Ditadura Científica: as relações entre o chefe republicano Julio de Castilhos e o Chefe de Polícia Cherobin da Costa

Revista Brasileira de História & Ciências Sociais, 2010
Rejane Penna, Cleusa Maria Graebin
doaj   +2 more sources

Sex‐specific associations between potentially traumatic events and cardiovascular disease in middle‐aged and older adults

Journal of Traumatic Stress, EarlyView.
Abstract Potentially traumatic events (PTEs) are associated with cardiovascular disease (CVD) in aging populations. Despite sex differences in PTE exposure and CVD incidence, no study has examined sex‐specific associations between PTEs and CVD in the same sample of middle‐aged and older adults.
Jeanine I. Nasser, Sophie M. Selbe, Kelsey N. Serier, Brian Shiner, Jennifer A. Sumner, Jaimie L. Gradus   +5 more
wiley   +1 more source