Results 171 to 180 of about 12,784 (283)

The Therapeutic Potential of Farm Dust Extracts in a Mouse Model of Eosinophilic Inflammation

open access: yesAllergy, EarlyView.
Farm dust extract (FDE) treatment reduces airway eosinophilia, mucus overproduction, and MHC‐II expression on DCs, limiting antigen presentation and Th2 inflammation. It increases PD‐L1 on DCs, promoting T cell deactivation. Additionally, FDE enhances Tregs and upregulates CTLA‐4, reinforcing suppression.
Rabia Ülkü Korkmaz   +16 more
wiley   +1 more source

Binding of Aryl Hydrocarbon Receptor (AhR) to AhR-interacting Protein [PDF]

open access: yesJournal of Biological Chemistry, 2000
David R. Bell, Alan Poland
openaire   +1 more source

Psychiatric disorders associated with increased risk of colorectal cancer in the UK biobank cohort. [PDF]

open access: yesSci Rep
Wang Z   +8 more
europepmc   +1 more source

Type I and II Interferons Drive Abacavir Hypersensitivity via Treg Suppression and T‐Cell Enhancement in Immunocompetent HLA‐Transgenic Mice

open access: yesAllergy, EarlyView.
Upregulated HLA‐B*57:01 expression in Tg/KO mice amplifies abacavir‐specific CD8+ T‐cell activation, driven by enhanced antigen presentation. Abacavir treatment induces robust pDC expansion and IFN‐α production, which selectively suppresses memory Treg populations.
SuJin Hwang   +8 more
wiley   +1 more source

Postbiotics and Nicotinamide Utilize Distinct Mechanisms to Improve Skin Barrier Integrity, Inflammation, and Keratinocyte Differentiation

open access: yesAllergy, EarlyView.
Integrating skin barrier measurements with omics and machine learning, we found that postbiotics and NAM regulate skin homeostasis through distinct, strain‐ and dose‐dependent mechanisms. Postbiotics primarily modulate skin barrier function by promoting keratinocyte differentiation and suppressing inflammation.
Yagiz Pat   +21 more
wiley   +1 more source

Evaluation of COTS Solutions to Support Flight Operations Quality Assurance in Business/Corporate Aviation [PDF]

open access: yes, 2018
Annex   +8 more
core   +2 more sources

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