Results 81 to 90 of about 8,340 (295)

An Integrative Strategy Delineates Modular Metabolic Remodeling and Potential Therapeutic Targets Across Metabolic Diseases

open access: yesAdvanced Science, EarlyView.
An integrative single‐cell atlas across multiple metabolic diseases reveals coordinated metabolic modules and disease‐shared versus disease‐specific pathway activities. By systematically comparing scoring strategies, a robust RankAve framework is established. Coupled with network analysis and drug‐target prediction, this resource uncovers cross‐disease
Kuan Yang   +10 more
wiley   +1 more source

Targeted Delivery of Indole‐3‐Pyruvic Acid Suppresses Macrophage Ferroptosis to Enhance CD8+ T Cell‐Mediated Immunotherapy Response in Bladder Cancer

open access: yesAdvanced Science, EarlyView.
A microbiota‐derived metabolite, indole‐3‐pyruvic acid, suppresses macrophage ferroptosis through the AHR–NF‐κB–SLC7A11 axis. This preserves CD8+ T cell function in bladder cancer. Macrophage‐targeted nanoparticles enhance indole‐3‐pyruvic acid delivery and overcome resistance to PD‐1 blockade.
Jianwen Lao   +15 more
wiley   +1 more source

Wybrane problemy kompensacji błędów bezkardanowego systemu nawigacji inercjalnej AHRS/INS [PDF]

open access: yes
The paper presents algorithms for compensating selected errors of the AHRS/INS system at various stages of its construction and testing. The object of the research was a laboratory model of the system built at the Air Force Institute of Technology ...
Borowski, Jerzy, Michalak, Sławomir
core   +1 more source

Slc44a2 Deficiency Unveils an IFN‐I–Dependent Feedback Control of pDC Egress

open access: yesAdvanced Science, EarlyView.
Working model of SLC44A2‐mediated maintenance of pDC homeostasis. This model illustrates two central mechanisms by which SLC44A2 regulates pDC homeostasis: (1) SLC44A2 limits IFN‐I production by exporting amino acids (T, N, Q), thereby preventing spontaneous pDC activation.
Ruiqun Chen   +11 more
wiley   +1 more source

Impact of human resource slacks on firm performance: Evidence from a developing country [PDF]

open access: yesZbornik radova Ekonomskog fakulteta u Rijeci : časopis za ekonomsku teoriju i praksu, 2013
Purpose of this paper is to investigate whether HR slack leads to improve firm performance, and what is the impact of HR slack in absolute and in relative terms on firm performance in a developing country.
M.M. Fonseka   +2 more
doaj  

Πλοήγηση UAV με χρήση AHRS [PDF]

open access: yes, 2015
Στα πλαίσια της διπλωματικής αυτής εργασίας δίνεται μια προσέγγιση στο κομμάτι της πλοήγησης ενός μη επανδρωμένου αεροσκάφους,αναλύεται η έννοια της αυτονομίας στην πλοήγηση με την χρήση ενός Συστήματος Αναφοράς “Συμπεριφοράς” και Κατεύθυνσης ...
Κατσούλης Παναγιώτης
core  

Talk to Your Data: An Agentic Artificial Intelligence‐Driven Decision‐Support Framework for Prosumer Energy Optimization and Recommendations

open access: yesAdvanced Intelligent Systems, EarlyView.
An agentic AI‐driven decision‐support framework for prosumers is proposed, integrating PV generation, load profiling, and multihorizon optimization within a four‐agent architecture. The approach significantly reduces grid dependence, enhances self‐sufficiency and prevents system oversizing.
Adela BÂRA, Simona‐Vasilica OPREA
wiley   +1 more source

AHR: A Temple of Tolerance to Toxemia [PDF]

open access: yesScience Translational Medicine, 2014
Signaling via the aryl hydrocarbon receptor minimizes the detrimental effects of infection without compromising the immune response to invading organisms.
openaire   +2 more sources

A MEMS-based Adaptive AHRS for Marine Satellite Tracking Antenna [PDF]

open access: yes, 2015
Satellite tracking is a challenging task for marine applications. An attitude determination system should estimate the wave disturbances on the ship body accurately.
Hussain, Dil Muhammed Akbar   +2 more
core   +1 more source

Animal models of idiopathic membranous nephropathy: Recent advances and future perspectives

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This review focuses on the evolution of idiopathic membranous nephropathy (IMN) animal models from traditional approaches (Heymann nephritis, C‐BSA, APA) to antigen‐specific models (PLA2R, THSD7A), critically evaluating their advances and limitations in replicating human IMN pathology.
Qiuying Liu   +6 more
wiley   +1 more source

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