Results 131 to 140 of about 688,717 (308)

Developing and Evaluating a Laboratory‐Based Frailty Index (FI‐Lab) for the Prediction of Long‐Term Health Outcomes in Systemic Lupus Erythematosus

Arthritis Care &Research, Accepted Article.
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical frailty index (FI).
Grace Burns, Samuel D. Searle, Alexandra Legge   +2 more
wiley   +1 more source

An AI Dietitian for Type 2 Diabetes Mellitus Management Based on Large Language and Image Recognition Models: Preclinical Concept Validation Study (Preprint)

, 2023
Haonan Sun, Kai Zhang, Wei Lan, Q. Gu, Guangxiang Jiang, Xue Yang, Wanli Qin, Dongran Han   +7 more
openalex   +1 more source

Pain and Patient‐Reported Physical Function Did Not Differ Between Body Composition Profiles in Patients with Hip Osteoarthritis

Arthritis Care &Research, Accepted Article.
Objective To explore whether higher body fat and lower lean mass are associated with greater pain and worse patient‐reported physical function in individuals with hip osteoarthritis (OA). A secondary aim was to examine whether pain and patient‐reported physical function differ according to four body composition profiles: high body fat, low lean mass ...
Alexandra Ryan, Boliang Wang, Fiona Dobson, Ben Kirk, Travis Haber, Kim L. Bennell, Shirley P. Yu, Kim Allison, Ricardo J.S. Costa, Gabrielle Knox, Michelle Hall   +10 more
wiley   +1 more source

Virtual screening-based discovery of AI-2 quorum sensing inhibitors that interact with an allosteric hydrophobic site of LsrK and their functional evaluation. [PDF]

Front Chem, 2023
Shi Q, Wen H, Xu Y, Zhao X, Zhang J, Li Y, Meng Q, Yu F, Xiao J, Li X.   +9 more
europepmc   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical applications, challenges, and future directions

Arthritis Care &Research, Accepted Article.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Clinical, histological, and serological predictors of renal function loss in lupus nephritis.

Arthritis Care &Research, Accepted Article.
Objective Kidney survival is the ultimate goal in lupus nephritis (LN) management, but long‐term predictors remain inadequately studied, requiring long‐term follow‐up. This study aimed to identify baseline and early longitudinal predictors of kidney survival in the Accelerating Medicines Partnership LN longitudinal cohort.
Shangzhu Zhang, Laurence Magder, Daniel Goldman, Judith A. James, Joel M Guthridge, Carla Guthridge, Peter Izmirly, Jill P Buyon, H.Michael Belmont, Richard A. Furie, Noa Schwartz, Chaim Putterman, Jennifer L. Barnas, Jennifer H. Anolik, Sarah French, Maria Dall'era, Avi Z. Rosenberg, Jeffrey Hodgin, Dawit S. Demeke, the Accelerating Medicines Partnership RA/SLE Network, Michelle Petri, Andrea Fava   +21 more
wiley   +1 more source

Discovery of AI-2 Quorum Sensing Inhibitors Targeting the LsrK/HPr Protein-Protein Interaction Site by Molecular Dynamics Simulation, Virtual Screening, and Bioassay Evaluation. [PDF]

Pharmaceuticals (Basel), 2023
Xu Y, Zeng C, Wen H, Shi Q, Zhao X, Meng Q, Li X, Xiao J.   +7 more
europepmc   +1 more source

Discordance between systemic lupus erythematosus disease activity index domain weights and their association with organ damage accrual

Arthritis Care &Research, Accepted Article.
Objective Studies of damage accrual in patients with systemic lupus erythematosus (SLE) show associations with disease activity measured by the SLE Disease Activity Index 2000 (SLEDAI‐2K), but these associations are imperfect. SLEDAI scores are powerfully influenced by weightings (1‐8) assigned to each domain.
Kevin Zhang, Eric F. Morand, Sarah E. Boyd, François Petitjean, Alberta Hoi, Rachel Koelmeyer, Iolanda Miceli, Julie A. Monk, Hieu T. Nim   +8 more
wiley   +1 more source

Molecular LEGION: incalculably large coverage of chemical space around the NLRP3 target

Scientific Data
The exploration and mapping of chemical space remain a central challenge in modern drug discovery. Traditional compound libraries and databases cover only a minute fraction of this space, limiting the discovery of novel, bioactive, and patentable ...
Bogdan Zagribelnyy, Vladimir Aladinskiy, Nikita Bondarev, Ivan Ilin, Maxim Malkov, Anna Vasileva, Xiaoyu Ding, Arkadii Lin, Rim Shayakhmetov, Alex Aliper, Feng Ren, Alex Zhavoronkov   +11 more
doaj   +1 more source

$$\mathrm{Q(AI)}^2$$: Quantum Artificial Intelligence for the Automotive Industry

KI - Künstliche Intelligenz
Published by Springer ...
Stollenwerk, Tobias, Bhattacharya, Somtapa, Cattelan, Michele, Ciani, Alessandro, Compostella, Gabriele, Headley, David, Klepsch, Johannes, Klusch, Matthias, Leder, Markus, Macaluso, Antonio, Michielsen, Kristel, Nabok, Dmytro, Papanikolaou, Anestis, Rausch, Alexander, Schumann, Marco, Skolik, Andrea, Yarkoni, Sheir, Wilhelm-Mauch, Frank   +17 more
openaire   +2 more sources