Results 31 to 40 of about 159,079 (225)

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Bridging the Vocabulary Gap: Using Side Information for Deep Knowledge Tracing

Applied Sciences
Knowledge tracing is a crucial task in personalized learning that models student mastery based on historical data to predict future performance. Currently, deep learning models in knowledge tracing predominantly use one-hot encodings of question ...
Haoxin Xu, Jiaqi Yin, Changyong Qi, Xiaoqing Gu, Bo Jiang, Longwei Zheng   +5 more
doaj   +1 more source

Exploring the AI competencies of elementary school teachers in South Korea

Computers and Education: Artificial Intelligence, 2023
Although the importance of K–12 artificial intelligence (AI) education grows, the lack of teacher readiness hinders the integration of AI in schools. To address this issue, this study aimed to explore South Korean elementary school teachers' experiences ...
Keunjae Kim, Kyungbin Kwon
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

AI in Higher Education

Journal of Ethics in Higher Education, 2023
This scholarly inquiry examines the interplay between artificial intelligence (AI) and academic integrity within higher education. Through a comprehensive synthesis of academic literature, the study delves into the multifaceted implications of AI tools ...
David S. Fowler
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

ChatCVD: A Retrieval-Augmented Chatbot for Personalized Cardiovascular Risk Assessment with a Comparison of Medical-Specific and General-Purpose LLMs

AI
Large language models (LLMs) are increasingly being applied to clinical tasks, but it remains unclear whether medical-specific models consistently outperform smaller, generalpurpose ones.
Wafa Lakhdhar, Maryam Arabi, Ahmed Ibrahim, Abdulrahman Arabi, Ahmed Serag   +4 more
doaj   +1 more source

EXPLORING NEW HORIZONS IN EDUCATION: SELF-DISCLOSED READINESS AND KEY ELEMENTS IN IMPLEMENTING AI FOR EDUCATIONAL PURPOSES [PDF]

Proceedings on Engineering Sciences
Modern developments in AI and machine learning have the possible ways to improve both the learning experiences for students and the capacity of educators.
Asma Abdulmana Alhamad
doaj   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source