Results 171 to 180 of about 407,626 (289)

Tacrolimus exposure during pregnancy in kidney and liver transplantation recipients: A comparison between whole blood and plasma concentration‐to‐dose ratios

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Tacrolimus monitoring is generally performed in whole blood (WB). Most (>85%) of circulating tacrolimus is bound to red blood cells. During pregnancy, WB monitoring might be suboptimal because of physiological changes including increased plasma volume and decreased haematocrit.
Jildau R. Meinderts, Paola Mian, Frederike G. I. van Vilsteren, Karien M. H. van de Wetering, Jelmer R. Prins, Stefan P. Berger, Daan J. Touw, Margriet F. C. de Jong   +7 more
wiley   +1 more source

Corrigendum to "Defining Relationships Among Tests for Kidney Transplant Antibody-Mediated Rejection" [<i>Kidney International Reports</i> Volume 10, Issue 9, September 2025, Pages 3225-3238]. [PDF]

Kidney Int Rep
Madill-Thomsen KS, Hidalgo LG, Demko ZP, Gauthier PM, Prewett A, Lowe D, Chang JJ, Mackova M, Budde K, Bromberg JS, Halloran PF, Trifecta-Kidney Study Group.   +11 more
europepmc   +1 more source

Innovations in the AIC of Russia

ТЕНДЕНЦИИ РАЗВИТИЯ НАУКИ И ОБРАЗОВАНИЯ, 2018
D. M. Akbasheva, A. Alieva
openaire   +1 more source

Pharmacokinetics and pharmacodynamics of intravenous and oral (S)‐ketamine: Investigating metabolite contribution to subjective effects

British Journal of Clinical Pharmacology, EarlyView.
Aims Oral administration of (S)‐ketamine for treatment‐resistant depression (TRD), as alternative to the registered intranasal or off‐label intravenous administrations, has high potential. However, it is characterized by an extensive first‐pass metabolism, resulting in low (S)‐ketamine exposure and high levels of active metabolites, including (S ...
Marije E. Otto, Gabriël E. Jacobs, Joost C. van Mechelen, Laura G. J. M. Borghans, Johan G. C. van Hasselt, Linda B. S. Aulin   +5 more
wiley   +1 more source

Azathioprine or mycophenolate mofetil for pediatric autoimmune cytopenia: a propensity score-matched study. [PDF]

Blood Adv
Pincez T, Fernandes H, Leverger G, Barlogis V, Fahd M, Garnier N, Paillard C, Guitton C, Abou Chahla W, Pasquet M, Jeziorski E, Castelle M, Bayart S, Pellier I, Thomas C, Pagnier A, Benadiba J, Li Thiao Te V, Cheikh N, Lejeune J, Deparis M, Marie-Cardine A, Chastagner P, Desplantes C, Millot F, Vic P, Thouvenin S, Piguet C, Pluchart C, Leblanc T, Héritier S, Aladjidi N.   +31 more
europepmc   +1 more source

Population pharmacokinetic/pharmacodynamic modelling to evaluate favipiravir in combination with lopinavir–ritonavir in patients with COVID‐19

British Journal of Clinical Pharmacology, EarlyView.
Aims The repurposed use of favipiravir in COVID‐19 has been reported to have limited clinical efficacy, yet it has been widely used in some countries. Favipiravir causes mutagenesis in RNA viruses, and it is currently unknown whether it may have a measurable effect on the virus in humans.
Akosua A. Agyeman, Laura Buggiotti, Li‐An K. Brown, Jose A. Guerra‐Assuncao, Japhette E. Kembou‐Ringert, Wen Y. Mak, Judith Breuer, David M. Lowe, Joseph F. Standing, FLARE Investigators   +9 more
wiley   +1 more source

Should we use fat-free mass or body mass and percentage body fat as separate predictors to predict maximum oxygen uptake? [PDF]

BMJ Open Sport Exerc Med
Nevill A, Harber M, Wyon M, Myers J, Arena R, Myers T, Kaminsky LA.   +6 more
europepmc   +1 more source

In aice le marbh

, 2021
openaire   +2 more sources

The decline of 6‐thioguanine nucleotides is not linked to impaired efficacy or safety of thiopurines in pregnant women with inflammatory bowel disease

British Journal of Clinical Pharmacology, EarlyView.
Background Thiopurines are used to maintain remission in inflammatory bowel disease (IBD). These drugs are metabolized into 6‐thioguanine nucleotides (6‐TGN), associated with efficacy, and 6‐methylmercaptopurine ribonucleotides (6‐MMPR), associated with adverse drug reactions. Pregnancy has been linked to a shift in thiopurine metabolism, characterized
Dianne G. Bouwknegt, Paola Mian, Femke Groen, Denise van den Berg‐Zuiddam, Andrea E. van der Meulen, Femke Crouwel, Nanne K. de Boer, Debbie S. Deben, Dennis R. Wong, Luc J. J. Derijks, Gerard Dijkstra, Arno R. Bourgonje, C. Janneke van der Woude, Marijn C. Visschedijk   +13 more
wiley   +1 more source

Comparison of Tools for Nutrition Assessment in Stable Subjects with Chronic Obstructive Pulmonary Disease: Which is the Best Mortality Predictor in Real Clinical Practice? [PDF]

Int J Chron Obstruct Pulmon Dis
Nishimura K, Kusunose M, Shibayama A, Nakayasu K.   +3 more
europepmc   +1 more source