Results 131 to 140 of about 5,495,408 (314)

Improving aid effectiveness in aid-dependent countries : lessons from Zambia [PDF]

open access: yes
Zambia was a middle-income country when it achieved independence from Great Britain in 1964. After decades of international aid Zambia has become a low-income country, and its per capita GDP is only now returning to the levels it had reached over forty ...
Gaël Raballand   +2 more
core  

Aid Scepticism and Effective Altruism [PDF]

open access: yes, 2019
In the article, ‘Being Good in a World of Need: Some Empirical Worries and an Uncomfortable Philosophical Possibility,’ Larry Temkin presents some concerns about the possible impact of international aid on the poorest people in the world, suggesting that
MacAskill, William
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Résilience et développement : complément, substitut ou palliatif ?

open access: yesRevue Internationale des Études du Développement, 2017
What political function does the omnipresent talk of “resilience” have in today’s development aid? This article analyses the discourse of some programs and aid projects, in the light of empirical research led over fifteen years within the sahelian ...
Véronique Ancey   +2 more
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Sub-regional Meeting on Disability Legislation: Decent Work for Persons with Disabilities in Asia, UN Conference Centre, Bangkok, Thailand, 23-24 June 2008 [PDF]

open access: yes, 2008
The Sub-regional Meeting on Disability Legislation, jointly organized by the ILO and the Office of the High Commissioner for Human Rights (OHCHR), took place in the framework of a technical cooperation project, “Promoting the Employability and Employment
ILO, Office of the High Commissioner for Human Rights (OHCHR) and Irish Aid
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Foreign Aid and Domestic Politics Implications for Aid Selectivity [PDF]

open access: yes
The links between foreign aid and policies in developing countries have been at the forefront of the policy debate for decades. An emerging consensus touts aid selectivity as the solution to the failures of conditionality.
Hagen, Rune Jansen
core  

HIV-AIDS

open access: yes, 2019
HIV-AIDS adalah penyakit infeksi yang disebabkan oleh infeksi Human Immunodeficiency Virus. HIV dapat ditularkan melalui seks, transfusi darah, berbagi jarum suntik dan penularan ibu-ke-bayi (perinatal). Faktor risiko heteroseksual adalah yang tertinggi, yaitu 82,8%, diikuti oleh homoseksual sebesar 7,4% dan perinatal sebesar 4,0%.
openaire   +3 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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