Results 241 to 250 of about 5,495,408 (314)

AIDS and aid.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2002
openaire   +1 more source

Hearing Aids

AJN, American Journal of Nursing, 1957
openaire   +3 more sources

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Mind-glucose control interplay in type 1 diabetes: management of exam-related stress using the MiniMed™ 780G insulin pump among high school students. [PDF]

Diabetol Metab Syndr
Elbarbary NS, Nagy N, Ismail LA, Abouelnasr SA, Ismail EAR.   +4 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Merging T1D and T2D Management: Shared Strategies for Common Goals-Building on Early Lessons From GLP-1 Trials in T1D. [PDF]

Diabetes Care
Bergenstal RM, Willis HJ, Carlson AL.
europepmc   +1 more source

Clientelism and Aid. [PDF]

Casamatta, Georges, Vellutini, Charles
core   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

My Heart and CKD: Pathway to Implementing a Decision Aid for Patients With CKD and Coronary Artery Disease. [PDF]

Can J Kidney Health Dis
Babione JN, Javaheri P, Kruger D, Wilson T, Pearson W, Loth M, March V, Gerber W, Har BJ, Graham MM, Wilton SB, Lewis KB, James MT.   +12 more
europepmc   +1 more source

Performance of an automated insulin-glucagon delivery system versus automated insulin delivery system during challenging inpatient conditions. A single-blind randomised controlled crossover trial. [PDF]

Diabetes Obes Metab
Ranjan AG, Laugesen C, Boiroux D, Schmidt S, Reenberg AT, Holst JJ, Jørgensen JB, Nørgaard K.   +7 more
europepmc   +1 more source