Results 271 to 280 of about 5,717,549 (296)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Pregnancy characteristics in patients with autoimmune diseases with different onset times and their relationship with pregnancy outcomes. [PDF]

BMC Pregnancy Childbirth
Xu Y, Ouyang H, Zhang M, Peng Y, Chen J, Liu S, Liu R, Song S, Hu G, Zhong M, Hu H.   +10 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Automated Insulin Delivery Systems Are Safe During Prolonged Religious Jewish Fasting Among Adolescents and Young Adults With Type 1 Diabetes. [PDF]

J Diabetes Sci Technol
Heifetz EM, Auerbach A, Avnon-Ziv C, Koolyk Fialkoff R, Levy-Khademi F.   +4 more
europepmc   +1 more source

Aid in Modulating the Impact of Terrorism on FDI: No Positive Thresholds, No Policy [PDF]

, 2017
Simplice Asongu, Uchenna Efobi, Ibukun Beecroft   +2 more
openalex  

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Visualizations during arithmetic tasks hamper performance and increase cognitive load in 9-year-olds: an fNIRS study. [PDF]

Front Psychol
Skau S, Karlsson J, Åsberg Johnels J, Helenius O.   +3 more
europepmc   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Immune exhaustion, the culprit for long COVID and chronic complications. [PDF]

J Leukoc Biol
Geng S, Li L.
europepmc   +1 more source