Results 171 to 180 of about 1,438,526 (344)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Mitochondrial Haplogroups and Left Ventricular Diastolic Dysfunction in People Living With and Without HIV. [PDF]

open access: yesJ Infect Dis
Cronin C   +19 more
europepmc   +1 more source

Series 2: Publications : AIDS Update, 1988-1994

open access: yes, 1993
Monthly newsletter describing news and events related to the AIDS Resource Center in Dallas, Texas as well as articles, letters, advice columns, and advertisements of interest to ...
AIDS Resource Center (Dallas, Tex.)
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Before and After Covid-19: What Has Changed in HIV Knowledge Level?

open access: yesJournal of Multidisciplinary Healthcare
Semiha Çelik Ekinci,1 Kazım Kıratlı2 1University of Health Sciences, Fatih Sultan Mehmet Training and Research Hospital, Department of Infectious Diseases and Clinical Microbiology, Istanbul, Turkey; 2Katip Celebi University, Ataturk
Çelik Ekinci S, Kıratlı K
doaj  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Communication Experiences of Patients With Hearing Loss During Hemodialysis Treatment and the Potential Role of Communication Tools: A Qualitative Study. [PDF]

open access: yesCan J Kidney Health Dis
DeBusschere A   +17 more
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

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