Results 61 to 70 of about 737,304 (290)

Purification tags markedly affect self‐aggregation of CPEB3

FEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito, Yujin Lee, Motoharu Ueno, Naotaka Sekiyama, Masatomo So, Ayako Furukawa, Kenji Sugase   +6 more
wiley   +1 more source

Clientelism and aid

Journal of Development Economics, 2008
Abstract Using a model of probabilistic voting, we analyze the impact of aid on the political equilibrium in the recipient country or region. We consider politicians with mixed motives: they are interested in promoting social welfare but also value the benefit of holding office.
Casamatta, Georges, Vellutini, Charles
openaire   +5 more sources

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

Drug-drug interactions between Highly Active Antiretroviral Therapy and Antiblastic chemotherapy in cancer patients with HIV infection

Frontiers in Pharmacology, 2016
The introduction of Highly Active Antiretroviral Therapy (HAART) into clinical practice has 27 dramatically changed the natural approach of HIV-related cancers. Several studies have shown that 28 intensive antiblastic chemotherapy (AC) is feasible in HIV-
Massimiliano eBerretta, Michele eCaraglia, Ferdinando eMartellotta, Silvia eZappavigna, Angela eLombardi, Carla eFierro, Luigi eAtripaldi, Tommaso eMuto, Daniela eValente, Paolo eDe Paoli, Umberto eTirelli, Raffaele eDi Francia   +11 more
doaj   +1 more source

Comparative State School Aids [PDF]

, 1921
Carter Alexander
openalex   +1 more source

Discussion on Artificial AIDS to Hearing [PDF]

, 1925
J. Kerr Love
  +10 more sources

Aids e a Aids das ciências [PDF]

História, Ciências, Saúde-Manguinhos, 1994
Este trabalho visa apresentar parte dos desenvolvimentos de uma pesquisa sobre a construção das doenças no discurso biomédico, partindo de uma abordagem ligada à sociologia do conhecimento, aqui definida como antiessencialista. Com o intuito de demonstrar algumas das questões teórico-metodológicas apontadas, os dados da pesquisa referentes ao ...
openaire   +4 more sources

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Associative aids: III. Their relation to the theory of thought and to methodology in psychology. [PDF]

, 1918
H. B. Reed
openalex   +1 more source