Results 181 to 190 of about 3,514,640 (196)

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Responding to the increase in substance use, HIV, HCV, and overdose in New England (RISE-NE): Protocol for a prospective cohort study. [PDF]

PLoS One
Biello KB, Bazzi AR, Dunham K, Goldman JE, Krieger MS, Silva V, Li Y, Mehta D, Nimoh M, Howe CJ, Beckwith CG, Singh D, Marshall BDL.   +12 more
europepmc   +1 more source

Confusion in evaluating research quality comes from lack of clarity: The case for explicit research questions. [PDF]

Am J Epidemiol
Fox MP, Wesselink A, Kezios KL, Jenson TE, Pescador-Jimenez M.   +4 more
europepmc   +1 more source

Dosimetric Outcomes of Definitive Radiation Therapy to Anal Squamous Cell Carcinoma in a Single Institution Using Volumetric Modulated Arc Therapy Evaluated Against Australian and International Treatment Planning Guidelines. [PDF]

J Med Radiat Sci
Alshamrani F, Hsieh M, Karl A, Chamberlain L, Greenham S, Goodworth J, Wood M, Shakespeare T, Le T, Tahir AM.   +9 more
europepmc   +1 more source

The effect of herpes zoster vaccines on incident dementia in England: Protocol for an OpenSAFELY regression discontinuity study

Walker V, Schaffer A, Hulme W, Wood C, Tamborska A, Walker A, MacKenna B, Goldacre B, Sterne J, Geldsetzer P.   +9 more
europepmc   +1 more source