Results 151 to 160 of about 3,902,056 (289)

The StrongWomen-Healthy Hearts program in Pennsylvania: RE-AIM analysis. [PDF]

open access: yesTransl Behav Med, 2015
Folta SC   +8 more
europepmc   +1 more source

Analysis of MIG Welding with Aim on Quality

open access: yes, 2008
Since 1987 Uddcomb Engineering has repaired pulps by their own developed overlay welding method even called Uddcomb method. Currently each welding machine is operated by two persons. To increase Uddcomb Engineering competitiveness the reduced number of operators is desired.
Svanberg, Niklas, Gertsovich, Irina
openaire   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Evaluation of a workplace intervention to promote commuter cycling: a RE-AIM analysis. [PDF]

open access: yesBMC Public Health, 2013
Dubuy V   +7 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Social Network Analysis: Applications: Event Programme

open access: yes, 2007
This seminar explores a number of current uses and applications of network analysis, including applications in social movement analysis, criminology, socio-linguistics and the study of literary networks.
Social Network, Analysis
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Do ownership structures affect the risk incentive provided by managerial portfolio holdings? An empirical analysis of UK alternative investment market companies

open access: yes, 2010
This paper analyzes the wealth and risk incentive effects of managerial options and shareholdings on the hedging probability of UK listed Alternative Investment Market (AIM) companies.
Pinto, Helena
core  

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