Results 21 to 30 of about 1,784,612 (269)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Substance flow analysis for mercury emission in Poland
E3S Web of Conferences, 2013 Substance Flow Analysis (SFA) is an approach showing main sources of emission and flows of pollution to the environment, which allows to define possible environmental risk.
Panasiuk D., Głodek A.
doaj +1 more source
Jurnal Sumberdaya Alam dan Lingkungan, 2017 Tujuan dari penelitian ini yaitu : 1) Untuk menentukan kebutuhan penggunaan air dalam rumah tangga di Kelurahan Bonipoi, Kota Kupang – NTT. 2) Untuk mengetahui tampungan efektif bedasarkan luasan atap rumah sebagai tampungan air hujan.
Gusminanti Kasdi +2 more
doaj +1 more source
Machine Learning in the Analysis of Carbon Dioxide Flow on a Site with Heterogeneous Vegetation
Information, 2023 The article presents the results of studies of carbon dioxide flow in the territory of section No. 5 of the Eurasian Carbon Polygon (Russia, Republic of Bashkortostan).
Ekaterina Kulakova, Elena Muravyova
doaj +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Liang you shipin ke-jiIn this paper, a new method has been proposed to determine the timing of reducing grain moisture ventilation by specific enthalpy and absolute humidity of air.
YIN Guo-bin
doaj +1 more source