Results 61 to 70 of about 1,112,972 (296)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

PEMANFAATAN BOTOL BEKAS SEBAGAI ALAT FILTER AIR SEDERHANA DAN RAMAH LINGKUNGAN UNTUK DESA LANGKAP KECAMATAN BANGSALSARI KABUPATEN JEMBER

open access: yesJurnal Hilirisasi IPTEKS, 2023
Kualitas air menjadi objek yang wajib diperhatikan sesuai dengan standar kesehatan dari Departemen Kesehatan karena kualitas air merupakan aspek krusial dalam menjaga kesehatan. Namun, ketersediaan air bersih yang seringkali terbatas, terutama di daerah
Evi Rohmatul Laili   +10 more
doaj   +1 more source

Filter cassette for high volume air sampler [PDF]

open access: yes, 1972
Filter cassette eliminates or substantially reduces contamination of filter media by extraneous material and facilitates ...
Burger, B. L.   +5 more
core   +1 more source

Determination of Soil-Water Characteristic Curves of Unsaturated Sandy Soils Using Membrane Filter with Stainless Wire Mesh [PDF]

open access: yes, 2009
Soil-water characteristic curve (SWCC) is an important soil function in an unsaturated soil mechanics field for design and analyses of any unsaturated earth structures. Determination of SWCC is not easy and more so time consuming. Generally, ceramic disc
Akudago, John Apambilla   +4 more
core   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

From Filter Paper to Functional Actuator by Poly(ionic liquid)-Modified Graphene Oxide

open access: yes, 2016
A commercially available membrane filter paper composed of mixed cellulose esters bearing typically an interconnected pore structure was transformed into a stimuli-responsive bilayer actuator by depositing a thin film of poly(ionic liquid)-modified ...
Antonietti, Markus   +3 more
core   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

Perancangan Filter Penjernih Air Sungai Kahayan Berbasis Pasir Silika dan Lempung Alam Asal Kalimantan Tengah [PDF]

open access: yes, 2019
Salah satu cara pengolahan air yang sederhana dan ramah lingkungan adalah melalui proses penyaringan dengan instalasi penyaringan air sederhana (IPAS) menggunakan bahan alam.
Coenraad, R. (Revianti)   +2 more
core  

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