Results 191 to 200 of about 138,734 (302)

Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus

Advanced Science, EarlyView.
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan, Dong Zhou, Ran Shao, Xing Liu, Jin Peng, Yingran Huang, Shuhui Qi, Cankun Xi, Menghang Wang, Bin Sun, Yinglin Qi, Xin Yin   +11 more
wiley   +1 more source

A Fully Biological Gas-Exchange Membrane toward a Biofabricated, Booster Lung. [PDF]

ACS Biomater Sci Eng
Comber EM, Roberts KG, Joyce IM, Palchesko RN, Shiwarksi DJ, Ren X, Feinberg AW, Cook KE.   +7 more
europepmc   +1 more source

Discovery of a Potent Fluorescence Polarization Probe for Identifying USP1 Allosteric Inhibitors

Advanced Science, EarlyView.
This study presents the first ubiquitin‐specific protease 1 (USP1) allosteric fluoroprobe and fluorescence polarization assay, enabling the differentiation of allosteric and catalytic site inhibitors. Further, a novel class of tetrahydroisoquinoline‐based USP1 inhibitors is designed, with compound 14a (USP1 IC50 = 29.9 nM) showing strong selectivity ...
Jiawei Cheng, Peipei Wang, Pengfei Wang, Jiamin Wang, Baiyang Li, Daqing Fang, Jian He, Xiaobei Hu, Weijuan Kan, Yubo Zhou, Chunpu Li, Jia Li, Hong Liu   +12 more
wiley   +1 more source

Gas Permeability of the Anisotropic Structure of a Frame Made of Concrete with the Addition of a Biocomponent-Application in Livestock Buildings. [PDF]

Materials (Basel)
Janowska-Renkas E, Fabianowski D, Klementowski I, Borek K, Koniuszy A, Wałowski G.   +5 more
europepmc   +1 more source

Electrostatic Self‐Assembly Induced Nest‐Like MXene Networks on Fabric for Ultra‐Broadband Flexible Absorption

Advanced Science, EarlyView.
In this study, an electrostatically self‐assembled WPU‐MXene@FC flexible fabric constructs a “nest‐like” structure on fibers, building construct MXene multiple loss paths, achieving ultra‐wideband absorption of 25.3–1200 GHz in a thickness of 1.8 mm, while also exhibiting superhydrophobicity, acid and alkali resistance, and bending resistance ...
Min Luo, Zihao Chen, Haotian Li, Kexun Li, Wei Wang, Weishi Jiao, Donghong Wang, Qiye Wen   +7 more
wiley   +1 more source

Electronic cigarette aerosols disrupt airway barrier function via MMP-dependent E-cadherin cleavage: findings from cell culture and murine models. [PDF]

Arch Toxicol
Beaumont AL, Ozeki SG, Lee CE, Chatburn RL, Bowler RP, Rezaee F.   +5 more
europepmc   +1 more source

Development of a Human 3D Immune‐Competent Neurovascular Model Enabling Time‐Resolved Monitoring of Neuroinflammatory Dynamics and Neuroimmune Interactions

Advanced Science, EarlyView.
Neuroinflammation alters blood–brain barrier integrity and contributes to neurological disorders, yet existing models lack human immune complexity. This study presents a 3D, immune‐responsive platform that reconstructs key neurovascular components and enables real‐time monitoring.
Pavlo Gordiichuk, Jing Bai, Olurotimi A. Bolonduro, Andrew M. Silverman, Robert Madison Green, Jason H. Lasser, Paul W. Fleming, Lishomwa C. Ndhlovu, James F. Saunders, Dmitry Shvartsman   +9 more
wiley   +1 more source

Air Permeability of Undisturbed Soils

Air Permeability of Undisturbed Soils
application/pdf 土壌の構造を乱さない採土試料について通気性の特性を研究した。充填試料との比較において，また透水性と比較しながら，さらに通気間ゲキの屈曲度を電気伝導度によって考察しながら，通気間ゲキの特性を次のようにまとめることができた。まず，土壌の通気性は透水性と同じように，ある圧力勾配の範囲内ではDarcy法則が適用でき，通気係数によって通気性を評価できることが実験的に確認された。また，空気間ゲキ率と通気係数の間にはそのままでは一定の関係が認め難いが，これは採土試料の状態では間ゲキ内に大気に開放されていない空気間ゲキが残されているためと考えられる。そこで，水で試料を飽和した後排水しながら開放状態をつくり，排水過程で空気間ゲキ率と通気係数の関係を求めた。その結果 ...
openaire  

Interplay between Host Structure, Oxygen Quenching, and Triplet-Triplet Annihilation Upconversion in Hybrid Polymer Hosts. [PDF]

ACS Appl Opt Mater
Burgoyne Morris GH, Gomes Franca L, Collins AR, Evans RC.   +3 more
europepmc   +1 more source

Thermal Resistance And Air Permeability of Wet Textiles

, 2015
Pichová Jana
core