Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Accelerating Instrument Troubleshooting: An AI-Driven Approach to Eliminating O2 Trap Breakthrough in GC-HDID Analysis [PDF]
The analysis of trace impurities in ultra-high purity oxygen (UPO) via GC-HDID is critically dependent on the O2 trap’s performance, where recurring breakthroughs pose a significant challenge.
Chang Chun-ling +2 more
doaj +1 more source
ABSTRACT Purpose Air pollution has been linked to several neurological conditions, including stroke and neurodegenerative diseases. Evidence regarding its association with multiple sclerosis (MS) remains conflicting, limited by small sample sizes. Methods PubMed, Embase, Scopus, and Cochrane controlled register of trials (CENTRAL) were searched on ...
Ahmad A. Toubasi, Thuraya N. Al‐Sayegh
wiley +1 more source
Infering Air Quality from Traffic Data using Transferable Neural Network Models [PDF]
This work presents a neural network based model for inferring air quality from traffic measurements. It is important to obtain information on air quality in urban environments in order to meet legislative and policy requirements.
A Pelliccioni +14 more
core +3 more sources
Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang +10 more
wiley +1 more source
Fine Particulate Matter and Ozone Air Quality in Western Pennsylvania in the 2000s [PDF]
Presents data on the area's particulate matter, ozone, and emissions levels and air pollution sources. Examines air quality compared with the rest of the nation, links between premature death and harmful levels of air pollution, and monitoring ...
John Graham
core
Teaching Electronics and Programming in Norwegian Schools Using the air:bit Sensor Kit
We describe lessons learned from using the air:bit project to introduce more than 150 students in the Norwegian upper secondary school to computer programming, engineering and environmental sciences.
Angelvik, Nina +8 more
core +1 more source
New Onset of Fibromyalgia After Exposure to a Combat Environment: A Longitudinal Cohort Study
Objective Traumatic life events are hypothesized to be triggers for the onset of fibromyalgia. Posttraumatic stress disorder (PTSD) is a common comorbidity of fibromyalgia. However, limited prospective data are available on the development of fibromyalgia after exposure to high‐magnitude stress.
Jay B. Higgs +15 more
wiley +1 more source
Purpose The study aimed to identify symptom‐based predictors of dry eye disease (DED) signs in the Sjögrens International Collaborative Clinical Alliance (SICCA) cohort. Methods Retrospective analysis examining 16 ocular symptoms (most graded 0‐4) and artificial tear (AT) use (graded 0‐3) as predictors of DED signs [abnormal ocular surface staining ...
Pragnya R Donthineni +7 more
wiley +1 more source
The differences between remote sensing and in situ air pollutant measurements over the Canadian oil sands [PDF]
Ground-based remote sensing instruments have been widely used for atmospheric research, but applications for air quality monitoring remain limited. Compared to an in situ instrument that provides air quality conditions at the ground level, most remote ...
X. Zhao +14 more
doaj +1 more source

