Results 101 to 110 of about 751,858 (288)

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

An Improved Air Health Index Based on Short-Term Cardiovascular Effects in Tianjin, China

open access: yesInternational Journal of Public Health
ObjectivesTo construct an improved air health index (AHI) based on cardiovascular years of life lost (YLL) in Tianjin and assess its utility.MethodsWe derived the exposure-response coefficients from time-series models and calculated the excess YLL (EYLL)
Mengnan Zhang   +5 more
doaj   +1 more source

Artificial Neural Network Based Early Warning System For Aydin Province Towards Air Factors Which Primarily Affect Human Health

open access: yesGazi Üniversitesi Fen Bilimleri Dergisi, 2017
Temperature, air quality index and ultraviolet index, which are basic air parameters, affect human health significantly. It is important to inform people about the precautions to be taken for these factors affecting human health at the primary level ...
Mahmut SİNECEN   +2 more
doaj   +1 more source

Reading, Writing, and Breathing [PDF]

open access: yes, 2005
This report looks at the distribution of air toxics, respiratory hazard, and school children in the state of California. The report finds evidence of disproportionate exposure and a potential link between such exposure and school-level academic ...
James Sadd   +2 more
core  

The air quality health index and emergency department visits for injury

open access: yesPolish Journal of Public Health, 2020
Abstract Introduction. The purpose of this study was to investigate the associations of ambient air quality with emergency department (ED) visits for injury. Aim. To explore correlations between ED visits for injury and ambient air pollution. Materials
openaire   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Tracking Oregon's Progress: A Report of the Tracking Oregon's Progress (TOP) Indicators Project [PDF]

open access: yes, 2014
In 1989, Oregon embarked on a novel experiment to track the progress of the state toward a set of economic, social and environmental goals embodied in the state strategic plan Oregon Shines.
Bruce Weber   +3 more
core  

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

Implementation of dataflow programming based Fuzzy Logic algorithm for gas concentration index in around of Sidoarjo mudflow, Indonesia

open access: yesMATEC Web of Conferences, 2018
Sidoarjo mudflow or known as Lapindo mudflow erupted since 2006. The Sidoarjo mudflow is located in Sidoarjo City, East Java, Indonesia. The mudflow-affected area has high air pollution level and high health risk. Therefore, in this paper was implemented
Widasari Edita Rosana   +3 more
doaj   +1 more source

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