Results 71 to 80 of about 4,405,851 (347)

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

A Multiaircraft Path Distributive Planning Method via Autonomous Self-Separation Operation Mode

Journal of Advanced Transportation
In this paper, a multiaircraft path planning method framework for autonomous operation and distributed decision-making was proposed. The core content of this framework consists of two parts: single-aircraft path planning and multiaircraft path ...
Ruiying Wen, Jiaxing He, Yupeng Guo, Hongyong Wang   +3 more
doaj   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Human Factors Analysis of the Improved FRAM Method for Take-Off Quality Lateral Shift

Applied Sciences, 2023
This article proposes an improved FRAM method based on the traditional FRAM method, using the study of aircraft take-off quality as an example to illustrate the operation method of the improved FRAM.
Wenjian Ouyang, Xusheng Gan, Yarong Wu, Kai Qu, Jiabo Wang   +4 more
doaj   +1 more source

The Effects of Traffic Related Air Pollution and Proposed Legal Remedies [PDF]

, 2017
This paper intends to examine the environmental issues that accompany air pollution generated from traffic related incidents, and the implications that this mass-generated pollution has on air quality, as well as the quality of life of humans exposed ...
Magi, Alessandro
core   +1 more source

A machine learning approach to air traffic interdependency modelling and its application to trajectory prediction

Transportation Research Part C: Emerging Technologies, 2019
Air Traffic Management is evolving towards a Trajectory-Based Operations paradigm. Trajectory prediction will hold a key role supporting its deployment, but it is limited by a lack of understanding of air traffic associated uncertainties, specifically ...
Christian Verdonk Gallego, V. F. G. Comendador, Manuel Angel Amaro Carmona, R. A. Valdés, F. S. Nieto, Miguel Garcia Martinez   +5 more
semanticscholar   +1 more source

Ionic‐Electronic Hydrogel‐Liquid Metal Composite Bilayer with Tissue‐Adaptive and Adhesive Properties for Closed‐Loop Neuroprosthetic System

Advanced Functional Materials, EarlyView.
A hydrogel–liquid metal composite peripheral nerve interface (HLB‐PNI) combines electrically durable electrodes and tissue‐adhesive hydrogel for tissue‐adaptive implantation. In nerve‐injured rats, it enables the diagnosis of sensory‐motor connectivity via stimulation and neural signal recording.
Yewon Kim, Kyoungryong Kim, Jaehyon Kim, Heewon Choi, Mikyung Shin, Donghee Son   +5 more
wiley   +1 more source

Optimal Configuration and Path Planning for UAV Swarms Using a Novel Localization Approach

Applied Sciences, 2018
In localization estimation systems, it is well known that the sensor-emitter geometry can seriously impact the accuracy of the location estimate. In this paper, time-difference-of-arrival (TDOA) localization is applied to locate the emitter using ...
Weijia Wang, Peng Bai, Hao Li, Xiaolong Liang   +3 more
doaj   +1 more source

Fuzzy Adaptive Finite-Time Tracking for Hypersonic Flight Vehicles Using Switching Event-Triggered Methodology

IEEE Access, 2022
The problem of event-triggered fuzzy adaptive finite-time tracking for flexible hypersonic flight vehicles is considered in this work. A new switching event-triggered mechanism is devised to mitigate the unnecessary resources waste in the process of ...
Xinlei Tang, Shen Di, Fuping Yu, Maolong Lv   +3 more
doaj   +1 more source

Empirical exploration of air traffic and human dynamics in terminal airspaces

, 2017
Air traffic is widely known as a complex, task-critical techno-social system, with numerous interactions between airspace, procedures, aircraft and air traffic controllers.
Han, Ke, Hu, Minghua, Yang, Lei, Yin, Suwan, Zhang, Honghai   +4 more
core   +1 more source