Results 31 to 40 of about 642,267 (308)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Research on UAV Conflict Detection and Resolution Based on Tensor Operation and Improved Differential Evolution Algorithm

Aerospace
With the widespread application of unmanned aerial vehicles (UAVs) in civilian and military fields, how to effectively detect and resolve conflicts of large-volume and high-density UAV flights in local airspace has become an important issue.
Zhichong Zhou, Guhao Zhao, Yiru Jiang, Yarong Wu, Jiale Yang, Lingzhong Meng   +5 more
doaj   +1 more source

Human Factors Analysis of the Improved FRAM Method for Take-Off Quality Lateral Shift

Applied Sciences, 2023
This article proposes an improved FRAM method based on the traditional FRAM method, using the study of aircraft take-off quality as an example to illustrate the operation method of the improved FRAM.
Wenjian Ouyang, Xusheng Gan, Yarong Wu, Kai Qu, Jiabo Wang   +4 more
doaj   +1 more source

Application of fuel/time minimization techniques to route planning and trajectory optimization [PDF]

, 1984
Rising fuel costs combined with other economic pressures have resulted in industry requirements for more efficient air traffic control and airborne operations.
Knox, C. E.
core   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Air Traffic Complexity Analysis in Multi-Airport Terminal Areas Based on Route Segment–Flight State Interdependent Network

Aerospace
An analysis of air traffic complexity in multi-airport terminal areas can assist air traffic controllers in accurately assessing the air traffic situation and collaboratively managing air traffic flows, thereby enhancing the utilization of airspace ...
Chuanlong Zhang, Xiangxi Wen, Minggong Wu, Libiao Zhang, Hanchen Xie, Lingzhong Meng, Jiale Yang   +6 more
doaj   +1 more source

Fuzzy Adaptive Finite-Time Tracking for Hypersonic Flight Vehicles Using Switching Event-Triggered Methodology

IEEE Access, 2022
The problem of event-triggered fuzzy adaptive finite-time tracking for flexible hypersonic flight vehicles is considered in this work. A new switching event-triggered mechanism is devised to mitigate the unnecessary resources waste in the process of ...
Xinlei Tang, Shen Di, Fuping Yu, Maolong Lv   +3 more
doaj   +1 more source

CARBOTRAF: A decision Support system for reducing pollutant emissions by adaptive traffic management [PDF]

, 2015
Traffic congestion with frequent “stop & go” situations causes substantial pollutant emissions. Black carbon (BC) is a good indicator of combustion-related air pollution and results in negative health effects.
Beckx, C, Dahlem, D, Elen, B, Hu, J, Kouwijzer, K, Litzenberger, M, Marcinek, M, Mascia, M, Mills, J, North, R, Theunis, J, van Poppel, M, Vranckx, S   +12 more
core  

Innovating Aircraft Repair Processes: The Role of Digitalization in Sustainability

Advanced Engineering Materials, EarlyView.
This research explores how digitalization—by storing detailed non‐destructive testing data in structured DICONDE databases and creating a standard data model of the component—innovates aviation maintenance and repair processes. Coupled with a developed state‐based simulation model, it enables data‐driven, sustainable repair strategies that reduce waste,
Johanna Aigner, Geo Jacob, Florian Raddatz, Gerko Wende   +3 more
wiley   +1 more source

Identification Method of Critical Routes in Aviation Network Based on Double Capacity Identification Standard

Hangkong gongcheng jinzhan, 2019
A method of identifying critical routes in the aviation network based on dual capacity identification standard is used for improving the singleness of the traditional identification method and incomplete evaluation index of network performance.
Li Jiawei, Liu Fei, Wu Minggong, Yu Minjian, Kang Runzhe   +4 more
doaj   +1 more source