Advanced Science, EarlyView.This study elucidates a novel mechanistic role of the deubiquitinase OTUD6A in asthma pathogenesis, uncovering its regulatory function in airway inflammation and airway remodeling through the stabilization of hResistin/mRELMα. This study offers a novel regulatory axis (OTUD6A‐hResistin/mRELMα) in asthma pathogenesis and OTUD6A inhibition as a potential
Weiting Pan +10 more
wiley +1 more source
AIR ACCESSIBILITY IN NORTHERN CANADA: PROSPECTS AND LESSONS FOR REMOTER COMMUNITIES [PDF]
This paper assesses the impact of Canada’s air transportation policy on air accessibility of remote and arctic communities in a context of liberalization of the aviation industry.
Alda Metrass Mendes +2 more
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New Tool Evaluates Health and Equity Impacts of Sacramento’s Regional Transportation Plans [PDF]
, 2018 There is growing value in developing regional transportation plans that foster safer, healthier, and more environmentally sustainable communities. Greater rates of active travel (walking and biking) can lead to improved health outcomes due to increases ...
Karner, Alex +4 more
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Advanced Science, EarlyView.This study presents a transferable modeling framework for carbon capture using aluminosilicates, integrating Universal Isotherm Modeling with experimental data. It reveals how ultramicropores, alumina content, and amine functionalization influence CO2 adsorption energetics.
Pooja Anil Kumar Nair +4 more
wiley +1 more source
Transportation Futures: Policy Scenarios for Achieving Greenhouse Gas Reduction Targets, MNTRC Report 12-11 [PDF]
, 2014 It is well established that GHG emissions must be reduced by 50% to 80% by 2050 in order to limit global temperature increase to 2°C. Achieving reductions of this magnitude in the transportation sector is a challenge and requires a multitude of policies ...
Kay, Andrew I. +3 more
core +1 more source
Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma
Advanced Science, EarlyView.Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian +7 more
wiley +1 more source
No Californian Left Behind: Clean and Affordable Transportation Options for All Through Vehicle Replacement [PDF]
, 2014 As California focuses in on new, high-tech, best-in-class transportation strategies, it risks leaving behind an important subset of households and communities who could most benefit from the transition to a cleaner, cheaper, and more sustainable ...
Cole Wheeler, Jesse Morris, Kate Gordon
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Clickable Microgel Inks Enable Spatioselective, Multi‐Stimuli Programmable Assembly of Materials
Advanced Science, EarlyView.Clickable microgel inks enable direct ink writing of hydrogel architectures with intrinsic spatioselective and programmable multi‐responsiveness. By combining pH‐responsive and temperature‐responsive microgel building blocks through Diels‐Alder interparticle crosslinking, the assemblies exhibit controllable swelling and shape changes.
Junho Moon +3 more
wiley +1 more source
TRANSPORTATION, AIR POLLUTION, AND PHYSICAL ACTIVITY (TAPAS), A SIX-CITY INTEGRATED HEALTH RISK ASSESSMENT PROGRAM OF ACTIVE TRAVEL POLICIES: COPENHAGEN CASE STUDY [PDF]
, 2011 Zorana Jovanovic Andresen +2 more
openalex +1 more source
Designing and Assessing a Teaching Laboratory for an Integrated Land Use and Transportation Course [PDF]
The intersection of land use and transportation policy is becoming an increasingly important focus for all urban planners. This focus, however, challenges the academic community to design effective courses that teach the concepts and professional skills ...
David King, David Levinson, Kevin Krizek
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