Results 111 to 120 of about 1,180,011 (399)

Validation of the Human Ozone Challenge Model as a Tool for Assessing Anti-Inflammatory Drugs in Early Development [PDF]

open access: yes, 2005
This study aimed to test the utility of the ozone challenge model for profiling novel compounds designed to reduce airway inflammation. The authors used a randomized, doubledummy, double-blind, placebo-controlled 3-period crossover design alternating ...
Gibson, Anthony   +9 more
core   +1 more source

Hydrogel Confinement Strategies for 3D Cell Culture in Microfluidic Systems

open access: yesAdvanced Materials Technologies, EarlyView.
Hydrogel confinement structures are key to organizing 3D cell cultures in microfluidic devices. This review classifies five structural strategies (micropillar, phaseguide, porous membrane, stepped‐height, and support‐free) and examines their trade‐offs alongside fabrication methods.
Soohyun Kim, Min Seok Lee, Sung Kyun Lee
wiley   +1 more source

Risk factors and outcomes for airway failure versus non-airway failure in the intensive care unit: a multicenter observational study of 1514 extubation procedures

open access: yesCritical Care, 2018
BackgroundPatients liberated from invasive mechanical ventilation are at risk of extubation failure, including inability to breathe without a tracheal tube (airway failure) or without mechanical ventilation (non-airway failure).
S. Jaber   +21 more
semanticscholar   +1 more source

Hard‐Magnetic Soft Millirobots in Underactuated Systems

open access: yesAdvanced Robotics Research, EarlyView.
This review provides a comprehensive overview of hard‐magnetic soft millirobots in underactuated systems. It examines key advances in structural design, physics‐informed modeling, and control strategies, while highlighting the interplay among these domains.
Qiong Wang   +4 more
wiley   +1 more source

Toward Wireless Implantable Robotic Systems Driven by Magnetic Field for Personalized Therapy

open access: yesAdvanced Robotics Research, EarlyView.
Robotic materials are playing an increasingly vital role in enabling sensing and actuation at small scales. This perspective highlights recent advances in magnetic materials and magnetically actuated devices for wireless sensing, actuation, and energy harvesting toward implantable robotic systems for closed‐loop therapy.
Yusheng Wang, Ruijian Ge, Xiaoguang Dong
wiley   +1 more source

Staphylococcus aureus and Chronic Airway Disease

open access: yesWorld Allergy Organization Journal, 2010
Staphylococcus aureus (S. aureus) is correlated with the development of persistent severe inflammatory disease of the upper airway including chronic rhinosinusitis with nasal polyps. This inflammation of the upper airways is characterized by a T-helper 2-
Lara. Derycke, PhD   +4 more
doaj   +1 more source

Agreement Among Radiographs, Fluoroscopy and Bronchoscopy in Documentation of Airway Collapse in Dogs. [PDF]

open access: yes, 2015
BackgroundAirway collapse is a common finding in dogs with chronic cough, yet the diagnosis can be difficult to confirm without specialty equipment.HypothesisBronchoscopic documentation of tracheobronchial collapse will show better agreement with ...
Johnson, LR, Pollard, RE, Singh, MK
core  

Enabling Real‐Time Shape‐Sensing in Soft Robots via a Miniaturized, Single‐Signal, Color‐Tuned Soft Optical Sensor

open access: yesAdvanced Robotics Research, EarlyView.
A miniaturized soft optical sensor that uses thin film color tuning enables real‐time 3D shape‐sensing from a single red–green–blue (RGB) signal. When integrated into a soft robot, it enables closed‐loop control and autonomous navigation in a phantom lung environment without the need for onboard electronics, achieving sub‐millimeter accuracy through ...
Frank Juliá Wise   +6 more
wiley   +1 more source

Transcriptomic characterization of the human segmental endotoxin challenge model

open access: yesScientific Reports
Segmental instillation of lipopolysaccharide (LPS) by bronchoscopy safely induces transient airway inflammation in human lungs. This model enables investigation of pulmonary inflammatory mechanisms as well as pharmacodynamic analysis of investigational ...
Christina Gress   +7 more
doaj   +1 more source

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