Results 141 to 150 of about 806,749 (357)
Developing Biomaterial‐Based mRNA Delivery System for Lung Disease Treatment
Advanced Science, EarlyView.Schematic illustration of biomaterial delivery mRNA for the treatment of lung diseases. Abstract Lung disease remains a persistent global health challenge. Advances in medical research have led to innovative strategies to combat these conditions, with biomaterials emerging as a promising platform for targeted drug delivery.
Qiancheng Gu +7 more
wiley +1 more source
Bronchodilator response patterns in patients with chronic airways obstruction: use of peak inspiratory flow rate. [PDF]
, 1967 K.B. Saunders
openalex +1 more source
Advanced Science, EarlyView.Engineered neutrophil‐derived vesicles (SOD2‐Fer‐1@CVs) co‐delivering antioxidant and ferroptosis‐inhibitory agents enable inflammation‐targeted, ROS‐responsive therapy for ischemia–reperfusion injury in lung transplantation. Synergizing with ex vivo lung perfusion, this strategy alleviates oxidative stress and inflammation, restores vascular integrity,
Hao‐Xiang Yuan +10 more
wiley +1 more source
CXCR1 Depletion in Ly6C+ cDC2 Alleviates Acute Lung Injury via Modulation of Th17/Treg Balance
Advanced Science, EarlyView.Pro‐inflammatory Ly6C⁺ cDC2s are identified as key effector cells mediating Cxcr1 signaling, driving the progression of ALI. Ly6C⁺ cDC2s release high levels of Il‐6 and Il‐1β, inducing Th17 differentiation. Cxcr1 deficiency reduces Il‐6 and Il‐1β production from Ly6C⁺ cDC2s through suppressing MEK1/ERK /NF‐κB signaling, thereby shifts naïve T cells ...
Shenghui Li +8 more
wiley +1 more source
Frontiers in ImmunologyBackground and purposeChronic rhinosinusitis with nasal polyps (CRSwNP) is a persistent inflammatory condition marked by high recurrence and limited therapeutic efficacy.
Shuman Li +8 more
doaj +1 more source
Frequency dependence of compliance as a test for obstruction in the small airways [PDF]
, 1969 Ann J. Woolcock +2 more
openalex +1 more source
Engineered Anti‐Senescence Trachea With Post‐Transplanted Regenerative Homeostasis
Advanced Science, EarlyView.Bioengineered trachea undergoes post‐transplanted senescence, which is found in this study for the first time. Hebe‐ET is designed with dual anti‐senescence strategies: fiber‐film scaffold in cartilage rings for close‐packed cell interaction, and quercetin‐loaded fibrous rings for immune modulation.
Ziyin Pan +14 more
wiley +1 more source
Effect of aerosol propellants and surfactants on airway resistance [PDF]
, 1969 G. M. Sterling, John Batten
openalex +1 more source
Advanced Science, EarlyView.This study presents a binary tumor‐microenvironment‐on‐a‐chip (T‐MOC) system incorporating multicellular tumor spheroids (MCTs) as an alternative preclinical platform to evaluate the efficacy of anticancer natural products. The T‐MOC model reproduces in vivo drug delivery barriers and physiological conditions, enabling morphological analysis to predict
Youngwon Kim +7 more
wiley +1 more source