Results 201 to 210 of about 832,675 (307)

Switching disease‐modifying therapies in patients with spinal muscular atrophy: A systematic review on effectiveness outcomes

British Journal of Clinical Pharmacology, EarlyView.
With multiple disease‐modifying therapies now available, treatment switching has become an important clinical consideration in the management of spinal muscular atrophy (SMA). While some switches are prompted by suboptimal clinical response, more commonly they are driven by treatment burden, convenience, or adverse events.
Andrej Belančić, Elvira Meni Maria Gkrinia, Patrick Eustaquio, Andrea Katrin Faour, Dinko Vitezić   +4 more
wiley   +1 more source

A Custom Annotated Dataset for Segmentation of Pulmonary Veins, Arteries, and Airways. [PDF]

Sci Data
Liu J, Zhang Z, Niu B, Kang S, Ren J, Wang L, Xu K.   +6 more
europepmc   +1 more source

P47 Pre and post simulation perceived anxiety and heart rate change in residents during management of a failed airway in obstetrics [PDF]

, 2019
Sree Kumar EJ, Makani Purva
openalex   +1 more source

Optimization of pharmaceutical research and development by early‐phase assessment of investigational medicinal products

British Journal of Clinical Pharmacology, EarlyView.
Small and mid‐sized pharmaceutical innovators often have limited in‐house health economics and market access expertise, and may struggle to align development strategies of investigational medicinal products with health system needs and payer expectations.
Zoltán Kaló, Attila Imre, Gábor Varga, Sándor Kovács, György Tímár, Balázs Nagy   +5 more
wiley   +1 more source

The role of neutrophils in bronchiectasis. [PDF]

Ann Med
Liang J, Bai X, Liu X.
europepmc   +1 more source

Exhaled carbon monoxide: a biomarker for assessing airway obstruction severity and exacerbation in chronic obstructive pulmonary disease

Walid I.M. Elgendy, Dalia Anas, Samah Lotfy   +2 more
openalex   +1 more source

210 KCNMA1 knockdown causes CFTR and mucociliary dysfunction in airway epithelial cells

, 2023
M. Kim, Nathalie Baumlin, N. Silswal, Makoto Yoshida, John S. Dennis, Matthias Salathé   +5 more
openalex   +1 more source

AZD0449, an inhaled JAK1 inhibitor, in healthy participants and patients with mild asthma

British Journal of Clinical Pharmacology, EarlyView.
Aims Inhaled corticosteroids (ICS) plus bronchodilator are recommended for the treatment of asthma. Targeting the JAK1‐dependent pathway may be an alternative for asthma management in patients with incomplete response to ICS. The aim of this study was to investigate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of AZD0449, a
Anna Lundahl, Rod Hughes, Joachim Almquist, David Close, Jukka Mäenpää, Ulrika Tehler, Tina Jellesmark Jensen, Szilárd Nemes, Anne‐Kristina Mercier, Zala Jevnikar, Pablo Forte Soto, Dave Singh   +11 more
wiley   +1 more source

Airway Proficiency and Efficiency Amongst Anesthesia Providers and Respiratory Therapists: A Comparison Study. [PDF]

J Clin Med
Brignull CG, Williams EB, Sprouse HA, Adams KJ, Tanner SL, Sykes JW, Moulder H, Hand WR, Morgan RR.   +8 more
europepmc   +1 more source

Virtual healthcare compared to hospital care for acute and post‐acute illness in adults: A systematic review and meta‐analysis of randomized controlled trials

British Journal of Clinical Pharmacology, EarlyView.
Aim To evaluate the clinical effectiveness, cost‐effectiveness, quality of life (QoL) and patient/caregiver satisfaction associated with VWs/HaH vs. traditional inpatient care in adults with acute or post‐acute illness. Methods We conducted a systematic review and meta‐analysis of randomized controlled trials (RCTs), following PRISMA 2020 guidelines ...
Rana A. Malhis, Stuart E. Bond, Ahmed A. Sadeq, Rani Shatnawi, Barbara R. Conway, Syed Shahzad Hasan, Mamoon A. Aldeyab   +6 more
wiley   +1 more source