Results 231 to 240 of about 800,967 (361)

Optimization of pharmaceutical research and development by early‐phase assessment of investigational medicinal products

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Small and mid‐sized pharmaceutical innovators often have limited in‐house health economics and market access expertise, and may struggle to align development strategies of investigational medicinal products with health system needs and payer expectations.
Zoltán Kaló   +5 more
wiley   +1 more source

AZD0449, an inhaled JAK1 inhibitor, in healthy participants and patients with mild asthma

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Inhaled corticosteroids (ICS) plus bronchodilator are recommended for the treatment of asthma. Targeting the JAK1‐dependent pathway may be an alternative for asthma management in patients with incomplete response to ICS. The aim of this study was to investigate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of AZD0449, a
Anna Lundahl   +11 more
wiley   +1 more source

Stridor and Upper Airway Obstruction in Infants

open access: bronze, 1969
E. J. BENNETT   +2 more
openalex   +1 more source

Basal cells as stem cells of the mouse trachea and human airway epithelium

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2009
J. Rock   +7 more
semanticscholar   +1 more source

Taking Down the Primary Cilium: Pathways for Disassembly in Differentiating Cells

open access: yesBioEssays, EarlyView.
Primary cilia are developmentally essential subcellular signaling compartments. However, many differentiated cells lack primary cilia, and cilia disassembly in these tissue contexts has been largely overlooked. We highlight several pathways for primary cilia loss and examine how changes in ciliation states could contribute to diverse pathologies ...
Carolyn M. Ott, Saikat Mukhopadhyay
wiley   +1 more source

Complications After a Mandibular Third Molar Extraction. [PDF]

open access: yesJ Am Coll Emerg Physicians Open
Kubota Y   +6 more
europepmc   +1 more source

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