Results 261 to 270 of about 832,675 (307)

The association between polypharmacy and mortality in patients with heart failure: Results from the PULSE dataset

ESC Heart Failure, EarlyView.
A study of 660 heart failure patients (mean age 76.1) found that polypharmacy was common, with only 5% discharged without it, and 60% had died by the end of a median 2.9‐year follow‐up. In patients with heart failure with reduced ejection fraction (HFrEF), hyperpolypharmacy was associated with significantly higher mortality, while in those with ...
Janine Beezer, Andrew L. Clark, Adam Todd, Andrew Kingston, Andrew Husband   +4 more
wiley   +1 more source

Beta‐blockers in patients with heart failure with reduced ejection fraction and concomitant chronic obstructive pulmonary disease: Cardiovascular and respiratory outcomes

European Journal of Heart Failure, EarlyView.
In total, 5084 patients from Swedish registries with both heart failure (HF) with reduced ejection fraction (HFrEF) and chronic obstructive pulmonary disease (COPD) were included. Confounding was handled by overlap weighting based on propensity scores for beta‐blocker use. Patients were followed up for 5 years, or until death, emigration from Sweden or
Benedikt N. Beer, Lina Benson, Christian Basile, Benedikt Schrage, Peter Moritz Becher, Stefan Blankenberg, Paulus Kirchhof, Barna Szabó‐Söderberg, Marco Metra, Anne Lindberg, Egidio Imbalzano, Giuseppe M. C. Rosano, Patric Karlström, Peter G.M. Mol, Raffaele Scorza, Lars H. Lund, Felix Lindberg, Gianluigi Savarese   +17 more
wiley   +1 more source

Comparison of airway opening pressure measurements: low-constant-flow vs. constant low-slope pressure ramp methods. [PDF]

BMC Anesthesiol
Tonai K, Shono A, Nakayama R, Katayama S.   +3 more
europepmc   +1 more source

Interpretation of in vitro concentration‐response data for risk assessment and regulatory decision‐making: Report from the 2022 IWGT quantitative analysis expert working group meeting

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal, Guangchao Chen, Kerry L. Dearfield, Min Gi, Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Alexandra S. Long, David P. Lovell, Barbara L. Parsons, Stefan Pfuhler, John Wills, Andreas Zeller, George Johnson, Paul A. White   +14 more
wiley   +1 more source

Author Correction: Evaluating physician concordance in interpretation of tracheobronchomalacia diagnosis and phenotyping using dynamic expiratory chest computed tomography. [PDF]

Sci Rep
Cortes-Puentes GA, Matatko M, Bartholmai BJ, Edell ES, Lim KG.   +4 more
europepmc   +1 more source

Progressive clonic slowing predicts severity of respiratory dysfunction and prolonged postictal immobility in tonic–clonic seizures

Epilepsia Open, EarlyView.
Abstract Objective Progressive clonic slowing is a common electroclinical phenomenon observed during the clonic phase of bilateral tonic–clonic seizures (BTCS) and reflects an inhibitory phenomenon. We aimed to explore the relationship between progressive clonic slowing and biomarkers implicated in the pathophysiology of sudden unexpected death in ...
John Phamnguyen, Fred Tremayne, Lata Vadlamudi, Cecilie Lander, Stephen Walsh, Xiaohua Chen, Alice‐Ann Sullivan, Viktor Vegh, David Reutens   +8 more
wiley   +1 more source

"Why Break the Y": A Novel Technique for Retrieval of an Impacted Airway Foreign Body.

J Indian Assoc Pediatr Surg
Marripati BK, Mishra A, Gaur SKS, Pandey V.   +3 more
europepmc   +1 more source

Transnasopharyngeal positive pressure ventilation during balloon dilation of severe subglottic stenosis in a low-weight infant: a case report. [PDF]

BMC Anesthesiol
Wang S, Wang C, Zhao W, Zhu X.
europepmc   +1 more source

Activating Ferroptosis of M1 Macrophages: A Novel Mechanism of Asiaticoside Encapsuled in GelMA for Anti‐Inflammation in Diabetic Wounds

Exploration, EarlyView.
Asiaticoside (AS) has known anti‐inflammatory effects in diabetic wounds, but the underlying mechanisms are still unclear. In this study, we reveal that AS alleviates inflammation in diabetic wounds by activating ferroptosis of M1 macrophages, which is attributed to the downregulation of ferroportin 1 and ferritinophagy‐induced degradation of ferritin ...
Shengnan Cui, Sheng Meng, Yong Liu, Shengqiu Chen, Wenzhi Hu, Qilin Huang, Ziqiang Chu, Weicheng Zhong, Liqian Ma, Zhe Li, Yufeng Jiang, Xi Liu, Xiaobing Fu, Cuiping Zhang   +13 more
wiley   +1 more source

Serum Retinol Levels and Risk of Asthma: Evidence From the NHANES and Mendelian Randomization

Food Frontiers, EarlyView.
The results of cross‐sectional studies and MR analysis support an association between serum retinol and the prevalence of asthma in adults. Higher serum retinol levels may serve as a protective factor against asthma. ABSTRACT Given the ongoing controversy regarding the relationship between serum retinol levels and asthma, this study aims to clarify ...
Xingyang Chen, Meichen Li, Boyang Qu, Yanrong Ao, Hong Gu, Yuan Tian, Yuan Song, Weiwei Cui   +7 more
wiley   +1 more source