Combating infections under siege: Healthcare challenges amidst the military assault in Gaza
Abstract The ongoing Israeli military assault on Gaza has caused a devastating collapse of healthcare infrastructure, resulting in an unprecedented surge in infectious diseases. The destruction of sanitation systems, restrictions on medical supplies, and displacement of civilians have created an environment conducive to the rapid spread of waterborne ...
Bilal Irfan+24 more
wiley +1 more source
Implications of Tobacco Use on Pathogen‐Driven Diseases: A Public Health and Policy Perspective
ABSTRACT The tobacco epidemic remains one of the most significant global public health challenges, responsible for over 8 million deaths annually, with a substantial portion occurring among non‐smokers exposed to second‐hand smoke. While cigarette smoking remains the most prevalent form of tobacco use worldwide, the rise of electronic nicotine delivery
Nadine Kabbani, James L. Olds
wiley +1 more source
The effect of rapid increase in desflurane and sevoflurane concentrations on spirometry in humans during balanced anesthesia with remifentanil [PDF]
De Baerdemaeker, Luc+3 more
core +1 more source
William A. Robson and the Making of English Administrative Law
This article examines the role of William A. Robson (1895‐1980) in the making of English administrative law. Criticising English common lawyers who believed that the growing responsibility of officials in law‐making and dispute resolution was a symptom of ‘administrative lawlessness’ that was sapping the foundations of English liberties, Robson argued ...
Martin Loughlin
wiley +1 more source
Judicial Review of the Improper Policy Implementation of Treaties
In recent years the courts of England and Wales have come to recognise a new iteration of judicial review which this article terms ‘review of improper policy implementation of treaties’ or ‘RIPIT’. RIPIT enables a reviewing court to scrutinise a domestic policy document which is promulgated for the purpose of securing compliance with a legislatively ...
Joanna Bell
wiley +1 more source
A Xanthine Derivative With Novel Heat Shock Protein 90‐Alpha Inhibitory and Senolytic Properties
This study aimed to find safe senolytic drugs that selectively eliminate senescent cells. Focusing on HSP90 inhibitors, we employed a virtual screening to identify novel, safer compounds (A). K5, a xanthinic candidate, effectively eliminated senescent cells in various cellular models (B), extended lifespan in flies, and reduced aging signs in mice (C).
Sandra Atlante+24 more
wiley +1 more source
Virus‐Induced Cellular Senescence Causes Pulmonary Sequelae Post‐Influenza Infection
Genetic or pharmacological depletion of senescent cells during influenza A virus infection led to complete recovery of the airway epithelium, indicating a marked acceleration of the epithelial repair process. Targeting senescent cells may represent a new preventive therapeutic option to reduce post‐influenza chronic lung damage.
Larissa Lipskaia+20 more
wiley +1 more source
Transcriptional Diversity in Response to Aging Across Skeletal Muscles
We constructed transcriptional maps of 11 skeletal muscles from young and old mice, revealing age‐related tissue‐specific gene expression changes. Our findings highlight cellular composition shifts and new cell states in aged muscles, providing insights into muscle aging and potential therapeutic targets for age‐related muscle disorders. ABSTRACT Aging
Can Liu+15 more
wiley +1 more source
A feedback-driven ventilation model for assessing airway secretions in mechanically ventilated patients. [PDF]
Anand DV+4 more
europepmc +1 more source