Results 221 to 230 of about 1,678,656 (298)

Triptolide Suppresses Tongue Squamous Cell Carcinoma Progression via PI3K–AKT Pathway Inhibition: An Integrative Network Pharmacology and Experimental Validation Study

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Tongue squamous cell carcinoma, the most aggressive subtype of oral squamous cell carcinoma, which is associated with high mortality, frequent recurrence, and early lymph‐node metastasis. Triptolide, a bioactive diterpenoid from Tripterygium wilfordii, exhibits broad anticancer activity.
Shan‐Shan Wang   +3 more
wiley   +1 more source

Transoral Ultrasound in the Diagnostic Workup of Peritonsillar Abscess—A Randomized Clinical Trial

open access: yesThe Laryngoscope, EarlyView.
Peritonsillar abscess frequently mimics peritonsillar cellulitis, exposing many patients to unnecessary and often painful blind needle aspirations. In this multicenter randomized clinical trial of 95 patients, adding transoral ultrasound to standard examination reduced needle aspiration attempts by nearly one third.
Tobias Todsen   +8 more
wiley   +1 more source

Superior Labial Artery Flap for Septal Perforation Repair: The Boxer's Flap

open access: yesThe Laryngoscope, EarlyView.
The nasal floor flap, or Boxer's flap, is an anteriorly pedicled, superior labial artery–based mucosal flap that provides excellent closure rates in septal perforation repair when traditional septal flaps are not feasible. The schematic shows: (A) preoperative perforation, (B) nasal floor flap elevation (with the pedicle maintained at the inferior ...
Nicholas J. Campion   +5 more
wiley   +1 more source

Office‐Based Pediatric Laryngospasm Simulation Case for OMS Residents

open access: yes
Journal of Dental Education, EarlyView.
Yuhyun Kim   +3 more
wiley   +1 more source

Thyroid Cartilage Reconstruction With Titanium Mesh in Advanced Papillary Thyroid Carcinoma

open access: yesThe Laryngoscope, EarlyView.
We report the first case of titanium mesh reconstruction of the thyroid cartilage following resection of papillary thyroid carcinoma with preservation of the laryngeal mucosa. This technique provided excellent functional outcomes while maintaining oncologic resection in a patient with locally advanced disease.
Anna Christina Clements   +5 more
wiley   +1 more source

Pregabalin Efficacy in Treatment of Chronic Neurogenic Cough

open access: yesThe Laryngoscope, EarlyView.
The use of neuromodulators for chronic cough has increased; however, the choice of medication, dosing regimen, and duration are still unclear. This longitudinal study of 95 adults taking pregabalin, 75 mg twice daily, for CNC demonstrated 78% improvement or resolution of cough, 17% unchanged, 1% worse cough, with a mean of 6 weeks of therapy, and only ...
Jacqui Allen   +3 more
wiley   +1 more source

Laryngeal Cryotherapy for Neurogenic Cough: Safety, Feasibility, and Prospective Outcomes

open access: yesThe Laryngoscope, EarlyView.
A prospective clinical trial investigated the safety and clinical outcomes of office‐based selective laryngeal cryotherapy for patients with refractory chronic cough. Patient were followed for 6 months posttreatment and had durable improvement in cough severity index and urge‐to‐cough scores and no serious long term adverse effects.
Shumon I. Dhar   +6 more
wiley   +1 more source

Design and Development of Novel Airway Device for Transoral Respiratory Monitoring During Sedation

open access: yesThe Laryngoscope, EarlyView.
This article describes iterative design factors and results of clinical testing for a novel medical device that promotes transoral respiratory gas exchange for patients during sedation. A minimally viable prototype was 3D printed from thermoplastic polyurethane and demonstrated high levels of oral retention, gas exchange, and satisfaction among ...
Samuel L. Oyer   +7 more
wiley   +1 more source

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