Results 41 to 50 of about 1,675,974 (298)

Comparison of Haemodynamic Responses to Laryngeal Mask Airway Insertion and Laryngoscopy with Endotracheal Intubation in Adults Undergoing Elective Surgery at Muhimbili [PDF]

, 2012
Airway management is of utmost importance during delivery of general anaesthesia. Traditionally, laryngoscopy and endotracheal tube (ETT) insertion has been the mainstay in providing adequate airway management and delivering anaesthesia.
Khalid, K.J., Khalid, Karima Jowhar
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Experiences of symptom burden among young children born with esophageal atresia–tracheoesophageal fistula: a US focus group study

Orphanet Journal of Rare Diseases
Background Children born with esophageal atresia–tracheoesophageal fistula (EA–TEF) can suffer from aerodigestive morbidity that impairs their quality of life and can persist into adulthood.
Michaela Dellenmark-Blom, John Bennett, Rosella Micalizzi, Lianne Cole, Kaylee Woods, Lauren Cardoni, Leah Frain, Abdimajid Mohamed, Jessica Yasuda, Peter Ngo, Anke Widenmann, Graham Slater, Benjamin Zendejas   +12 more
doaj   +1 more source

Anaesthetic Management of Acquired Tracheal Stenosis for Tracheal Resection and Reconstruction

Airway, 2021
Tracheal resection is a rare and complex surgery. The critical phases of the surgery are during induction in the presence of a critical airway, intraoperatively during airway transection and postoperatively for the maintenance of the reconstructed airway
Jacob Mathew, Sunil Rajan, Beegam Shoufi Kunjumon, Lakshmi Kumar   +3 more
doaj   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

SPP1 promotes lymph node metastasis and malignant progression of head and neck squamous cell carcinoma by activating FAK-AKT signaling pathway

World Journal of Surgical Oncology
Background Lymph node metastasis is a critical determinant of poor prognosis in head and neck squamous cell carcinoma (HNSCC). Secreted phosphoprotein 1 (SPP1) has been implicated in the progression of multiple malignancies; however, its clinical ...
Jingyan Li, Min Pan, Mengna Wang, Tianhao Wu, Youlan Zhang, Zhihai Wang, Quan Zeng   +6 more
doaj   +1 more source

Tracheoesophageal fistula repair with veno-venous extracorporeal support and Montgomery T-tube: a case report

The Journal of ExtraCorporeal Technology
Tracheoesophageal fistulas (TEFs) are a major surgical challenge requiring a meticulous approach. This case report describes the successful surgical treatment of a 50 mm TEF extending from the upper third of the trachea to 40 mm above the main carina in ...
Che Morales José Luis, Vargas Mendoza Gary Kosai   +1 more
doaj   +1 more source

Obstructive Sleep Apnoea: a dental perspective [PDF]

, 2003
Obstructive sleep apnoea (OSA) is regarded as a potentially life threatening breathing disorder characterised by periodic cessation of air intake during sleep.
Mulligan, Kevin M.
core  

Electrospun Core–Shell Bioadhesive Nanofiber Sheets Enable Durable Pulmonary Air Leak Sealing Under Wet and Dynamic Conditions

Advanced Healthcare Materials, EarlyView.
A core–shell electrospun nanofiber sheet provides strong adhesion and durable sealing on the wet and dynamic lung surface. The engineered fibrous architecture maintains airtight integrity and offers a potential alternative to fibrin sealants for pulmonary air leak management in thoracic surgery.
Tomohito Okubo, Kouji Hara, Naoyuki Hatayama, Kota Takahashi, Eriko Yamazoe, Takaaki Ito, Takao Takeuchi, Yoko Koide, Mayumi Yamada, Munekazu Naito, Kohei Tahara   +10 more
wiley   +1 more source

Parents’ experiences of condition management in children born with esophageal atresia-tracheoesophageal fistula during their early childhood

Orphanet Journal of Rare Diseases
Background Esophageal atresia-tracheoesophageal fistula (EA-TEF) is a rare congenital malformation of the esophagus and airways. Following surgical repair, children commonly face ongoing aerodigestive morbidity.
Michaela Dellenmark-Blom, Lianne Cole, Rosella Micalizzi, John Bennett, Kaylee Woods, Lauren Cardoni, Leah Frain, Abdimajid Mohamed, Jessica Yasuda, Peter Ngo, Anke Widenmann, Graham Slater, Benjamin Zendejas   +12 more
doaj   +1 more source