Results 71 to 80 of about 325,957 (305)

Navigating adverse immunostimulation: A practical guide for clinical researchers

British Journal of Clinical Pharmacology, EarlyView.
Problem Setting As drug development moves towards more complex products, early clinical development programmes are increasingly hampered by unwanted and/or unexpected activation of the immune system (adverse immune stimulation, AIS). Solution At the Centre for Human Drug Research, we have introduced standardized procedures to make AIS manageable, while
Juliette A. van den Noort, Anouk C. Meijs, Naomi B. Klarenbeek, Matthijs Moerland   +3 more
wiley   +1 more source

A bibliometric analysis of literature on accounting information systems: trends, future and direction [PDF]

Contabilitate şi Informatică de Gestiune
Research Questions: What has been the trend and development in research publications concerning Accounting Information Systems (AIS) over the past decade? Which authors, countries, and scholarly journals have made significant contributions to the body of
Justice Stephen Tetteh Zotorvie, James Dickson Fiagborlo, Edward Sedzro   +2 more
doaj   +1 more source

Adverse immunostimulation in early phase clinical trials: Key findings and recommendations based on the investigator's clinical experience

British Journal of Clinical Pharmacology, EarlyView.
Problem setting The emergence of therapeutic proteins has coincided with an increase of acute adverse immunostimulation (AIS). AIS has occured in clinical trials despite compliance with regulatory guidelines on preclinical evaluation and its incidence is anticipated to increase even further.
Juliette A. van den Noort, Marella C. E. van Ruissen, Lisanne C. A. Smidt, Naomi B. Klarenbeek, Philip H. K. Kremer, Manon A. A. Jansen, Jacobus Burggraaf, Joop M. A. van Gerven, Matthijs Moerland   +8 more
wiley   +1 more source

Calibration of AIS Data Using Ground-based Spectral Reflectance Measurements [PDF]

, 1985
Present methods of correcting airborne imaging spectrometer (AIS) data for instrumental and atmospheric effects include the flat- or curved-field correction and a deviation-from-the-average adjustment performed on a line-by-line basis throughout the ...
Conel, J. E.
core   +1 more source

Understanding the influence of transfusion and blood loss on tranexamic acid concentration in scoliosis surgery with blood loss

British Journal of Clinical Pharmacology, EarlyView.
Aims Tranexamic acid (TXA) stabilizes clot formation by inhibiting fibrin degradation and improves postoperative outcomes. However, rare adverse events (e.g., thrombosis, seizures) warrant dose–risk evaluation. This study examines how perioperative blood loss and transfusion practices affect TXA concentrations during paediatric scoliosis surgery ...
Paula Alexandra Sá, Luisa Barreiros, Marcela A. Segundo, Eugénia Cruz, Sibylle Langenecker   +4 more
wiley   +1 more source

AIS Investigation of Agricultural Monocultures [PDF]

, 1985
Airborne Imaging Spectrometer (AIS) data were acquired over an agricultural area in eastern San Joaquin County, California in July, 1984. Cover type information was subsequently collected for all fields along this flight line. The lack of detailed ground
Wood, B. L., Wrigley, R. C.
core   +1 more source

Propionibacterium acnes infections in patients with idiopathic scoliosis: a case-control study and review of the literature. [PDF]

, 2018
Purpose:Surgical site infection (SSI) caused by Propionibacterium acnes is an infrequent but devastating complication after spinal fusion. The purpose of this study was to identify risk factors for SSI with Propionibacterium acnes after spinal fusion for
Blanco, J, Gruskay, J, Perlman, S, Price, M, Swarup, I, Widmann, R, Yang, J   +6 more
core   +2 more sources

Prioritizing Feasible and Impactful Actions to Enable Secure AI Development and Use in Biology

Biotechnology and Bioengineering, EarlyView.
ABSTRACT As artificial intelligence continues to enhance biological innovation, the potential for misuse must be addressed to fully unlock the potential societal benefits. While significant work has been done to evaluate general‐purpose AI and specialized biological design tools (BDTs) for biothreat creation risks, actionable steps to mitigate the risk
Josh Dettman, Emily Lathrop, Aurelia Attal‐Juncqua, Matthew Nicotra, Allison Berke   +4 more
wiley   +1 more source

High Resolution Spectrometry of Leaf and Canopy Chemistry for Biochemical Cycling [PDF]

, 1985
High-resolution laboratory spectrophotometer and Airborne Imaging Spectrometer (AIS) data were used to analyze forest leaf and canopy chemistry. Fundamental stretching frequencies of organic bonds in the visible, near infrared and short-wave infrared are
Acevedo, W., Matson, P., Peterson, D. L., Spanner, M. A.   +3 more
core   +1 more source

Predicting Destinations by Nearest Neighbor Search on Training Vessel Routes

, 2018
The DEBS Grand Challenge 2018 is set in the context of maritime route prediction. Vessel routes are modeled as streams of Automatic Identification System (AIS) data points selected from real-world tracking data.
Amariei, Ciprian, Diac, Paul, Onica, Emanuel, Roşca, Valentin   +3 more
core   +1 more source