Results 61 to 70 of about 809,589 (339)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Chemical patterning for the highly specific and programmed assembly of nanostructures [PDF]

, 2005
We have developed a new chemical patterning technique based on standard lithography-based processes to assemble nanostructures on surfaces with extraordinarily high selectivity.
Alivisatos, Arun Majumdar, Balaji Kannan, Halperin, Hoff, Kannan, Kenneth Castelino, Mirkin, Pallandre, Rajan P. Kulkarni, Sharma, Srinath Satyanarayana, Zhang   +12 more
core   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Study of optical properties of si-al-n coatings obtained by magnetron sputtering [PDF]

, 2016
The results of the investigation of structural-phase state and optical properties of the coatings on thebasis of Si-Al-N, deposited on quartz glass by pulsed magnetron sputtering were presented.
Першукова, А. Г., Рыбалко, Е. В.   +1 more
core  

Thin film diffusion barrier formation in PDMS microcavities [PDF]

, 2009
We describe a method to form glass like thin film barrier in polydimethylsiloxane (PDMS) microcavities. The reactive fragments for the surface reaction were created from O2 and hexamethyldisiloxane (HMDS) in RF plasma environment.
Basabe-Desmonts, Lourdes, Daniels, Stephen, Dimov, Ivan Krastev, Ducrée, Jens, Gandhiraman, Ram Prasad, Lee, Luke P., Riaz, Asif, Ricco, Antonio J.   +7 more
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Effect of Heat Treatment Temperature on the Coating Microstructure and Properties of Thin Al-Si Coated Hot Formed Steel [PDF]

Cailiao Baohu
For investigating the optimal surface properties of thin aluminum-silicon coated steel plate after hot forming，the Al-10Si thin coated hot formed steel plate was taken as the research object， and the effects of different heat treatment temperatures on ...
XU Wenhui, LU Jiashun, YANG Honggang, JIN Yong, XU Chengming, WANG Yongming
doaj   +1 more source

Improvement of High Temperature Oxidation of Low Carbon Steel Exposed to Ethanol Combustion Product at 700 °C by Hot-dip Aluminizing Coating [PDF]

, 2011
Low carbon steel (AISI 1005) was coated by hot-dipping into a molten Al-10% Si bath at 700 °C for 18s. After hotdipping treatment, the coating layers consisted of Al, Si, FeAl3, τ5-Fe2Al8Si, and Fe2Al5. The bare steel and thealuminized steel were
Badaruddin, M. (Mohammad)
core  

Tribocorrosion Properties of PEO Coatings Produced on AZ91 Magnesium Alloy with Silicate- or Phosphate-Based Electrolytes [PDF]

, 2018
In this work, the tribocorrosion behavior of plasma electrolytic oxidation (PEO)-coated AZ91 samples was studied. In particular, two different coatings were produced and compared. One was obtained with an alkaline electrolyte containing sodium phosphate,
Brunelli, Katya, Dabala', Manuele, Gennari, Claudio, Marco, Sinico, Pezzato, Luca, Pietro, Pranovi, Settimi, ALESSIO GIORGIO, Vranescu, Dragos   +7 more
core   +2 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source