Results 371 to 375 of about 17,175,483 (375)

Immune mechanisms of AL amyloidosis

Drug Discovery Today: Disease Mechanisms, 2004
Light chain amyloidosis (AL) is both a disorder of protein conformation and a plasma cell dyscrasia, with secretion of altered light chains that polymerize systemically into amyloid fibrils leading to organ failure. Knowledge of the biological features of amyloid cells and of the mechanisms determining light chain organ targeting and cytotoxicity is ...
Perfetti V, PALLADINI, GIOVANNI, MERLINI, GIAMPAOLO   +2 more
openaire   +2 more sources

An N-glycosylation hotspot in immunoglobulin κ light chains is associated with AL amyloidosis

Leukemia, 2022
Alice Nevone, M. Girelli, S. Mangiacavalli, B. Paiva, P. Milani, Pasquale Cascino, Maggie Piscitelli, V. Speranzini, C. Cartia, P. Benvenuti, I. Goicoechea, F. Fazio, M. Basset, A. Foli, M. Nanci, Giulia Mazzini, Serena Caminito, M. Sesta, Simona Casarini, Paola Rognoni, F. Lavatelli, M. Petrucci, P. Olimpieri, S. Ricagno, L. Arcaini, G. Merlini, G. Palladini, M. Nuvolone   +27 more
semanticscholar   +1 more source

Amyloidosis of pancreatic islets in primary amyloidosis (AL type)

Pathology International, 2005
Seven cases of primary amyloidosis (AL‐type) were studied immunocytochemically for the possible involvement of pancreatic islets. The two cases with extensive organ involvement by AL‐amyloidosis revealed amyloid deposits in pancreatic islets by routine HE and Congo red staining, which were positive for amyloid p and amyloid a, but were only focally ...
openaire   +3 more sources

Daratumumab for AL amyloidosis

Nature Reviews Nephrology, 2021
openaire   +3 more sources

AL amyloidosis

Medicine, 2013
openaire   +1 more source