Results 111 to 120 of about 216,053 (314)

Maximal use of 0.05% topical isotretinoin in patients with congenital ichthyosis results in low systemic exposure

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Congenital ichthyoses (CI) are rare, inherited skin disorders characterized by hyperkeratosis, scaling and fissuring that significantly impair patients' quality of life. Treatment options are limited, with systemic retinoids reserved for severe cases owing to their adverse effect profile.
Holm Schneider   +10 more
wiley   +1 more source

‘Literal torture’: Vulnerability, resilience and young people's experiences of pressure in physical education

open access: yesBritish Educational Research Journal, EarlyView.
Abstract This paper combines vulnerability and resilience theory to explore the pressure young people experience in Physical Education (PE) and sport at secondary school. The theoretical framework was used to understand both how young people experience PE in school and how vulnerability and resilience function interdependently in social contexts like ...
David Littlefair, Michael Jopling
wiley   +1 more source

Targeting C1q prevents microglia-mediated synaptic removal in neuropathic pain

open access: yesNature Communications
Activation of spinal microglia following peripheral nerve injury is a central component of neuropathic pain pathology. While the contributions of microglia-mediated immune and neurotrophic signalling have been well-characterized, the phagocytic and ...
Noosha Yousefpour   +27 more
doaj   +1 more source

‘Fish in simulated water’? A Bourdieusian analysis of Chinese doctoral students' learning experiences in Southeast Asian developing countries

open access: yesBritish Educational Research Journal, EarlyView.
Abstract International student mobility (ISM) has historically followed a pattern of movement from developing regions to developed countries. However, in recent years, there has been a noticeable increase in the number of Chinese students pursuing doctoral studies in Southeast Asian developing countries, an area that has received relatively little ...
Yueyang Zheng   +2 more
wiley   +1 more source

Effectiveness of Scientific Literacy and Communication E‐Modules in a Molecular Biology Course: A Qualitative and Quantitative Analysis

open access: yesBiochemistry and Molecular Biology Education, EarlyView.
ABSTRACT In previous work, we described the development and implementation of new pedagogical practices aimed at enhancing literacy, critical thinking, and communication skills development in a third‐year undergraduate molecular biology course. The online nature and large size of the course presented challenges regarding student engagement and access ...
Meghan Kates   +7 more
wiley   +1 more source

Early evolutionary history of the seed

open access: yesBiological Reviews, EarlyView.
ABSTRACT The seed is an essential stage in the life history of gymnospermous and angiospermous plants, facilitating both their survival and dispersal. We reappraise knowledge of the evolutionary history of the gymnospermous seed, from its origin in the late Devonian through to the well‐known end‐Permian extinctions – an interval encompassing the ...
Richard M. Bateman   +2 more
wiley   +1 more source

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