Results 41 to 50 of about 216,053 (314)

Potential causes for the stranding of Macrohectopus branickii (Dybowsky, 1874) specimens along the Angara River: strong currents, artificial lighting, or ice melting

open access: yesActa Biologica Sibirica
Macrohectopus branickii (Dybowsky, 1874) is the world's only freshwater pelagic amphipod native to Lake Baikal. The habitat of this amphipod is limited to the pelagic zone of Lake Baikal (with periodic nocturnal migrations to the littoral part of the ...
Maria A. Maslennikova   +10 more
doaj   +1 more source

Restriction of Individual Branched‐Chain Amino Acids has Distinct Effects on the Development and Progression of Alzheimer's Disease in 3xTg Mice

open access: yesAdvanced Science, EarlyView.
Protein restriction (PR) slows Alzheimer's disease (AD) in mice, and other benefits of PR are due to decreased branched‐chain amino acids (BCAAs). We show that restricting any BCAA has benefits, with sex‐ and BCAA‐specific impacts on pathology, molecular signaling, and cognition.
Reji Babygirija   +22 more
wiley   +1 more source

On the Origins of Toughness in Corymbia calophylla (Marri Tree) Nuts

open access: yesAdvanced Science, EarlyView.
We uncover the natural toughening mechanisms of the marri nut, including fiber pullout, crack deflection, and a viscoelastic matrix, which enable exceptional energy absorption and ductility comparable to Teflon, with an elastic modulus similar to acrylic.
Wegood M. Awad   +7 more
wiley   +1 more source

Bir Sembolik İktidar Biçimi Olarak Kan Davaları: Şan, Şeref ve Namus

open access: yesSelçuk Üniversitesi Edebiyat Fakültesi Dergisi
Kan davaları, toplumsal alana büyük etkileri itibariyle önemli bir yere sahiptir. Ekonomik, sosyal ve kültürel kayıplar, kan davalarının olağan ve beklenilen ve hatta istenilen yansımalarıdır.
İlhami Aydın
doaj   +1 more source

Lipid‐Facilitated Opening of the ADAM10 Sheddase Revealed by Enhanced Sampling Simulations

open access: yesAdvanced Science, EarlyView.
Phosphatidylserine acts as a lipid trigger to enhance activation of the sheddase ADAM10. By integrating fluorescence spectroscopy assays with enhanced sampling molecular dynamics simulations, this study shows that phosphatidylserine promotes ADAM10 catalytic activity along with expansion of its extracellular domains, enhancing accessibility to scaffold
Adrien Schahl   +7 more
wiley   +1 more source

Two Distinct Phonon Wave Effects Control Thermal Transport across the Coherent–Incoherent Regime in Superlattices

open access: yesAdvanced Science, EarlyView.
Thermal transport in smooth‐interface superlattices is studied using the phonon Wigner transport equation, which captures both particle‐like and wave‐like contributions. A minimum in cross‐plane thermal conductivity emerges with increasing period thickness, signaling a crossover from coherent to incoherent phonon transport.
Jin Yang   +3 more
wiley   +1 more source

How to co-create content moderation policies: the case of the AutSPACEs project

open access: yesData & Policy
The moderation of user-generated content on online platforms remains a key solution to protecting people online, but also remains a perpetual challenge as the appropriateness of content moderation guidelines depends on the online community that they aim ...
Georgia Aitkenhead   +11 more
doaj   +1 more source

Intracellular mGluR5 plays a critical role in neuropathic pain

open access: yesNature Communications, 2016
mGluR5 has been shown to play a role in chronic pain regulation. Here, the authors use membrane permeable and non-transported, impermeable mGluR5 antagonists to show that spinal analgesic effects in vivoare mediated by intracellular rather than cell ...
Kathleen Vincent   +10 more
doaj   +1 more source

Overlapping Limitations for ps-Pulsed LIFT Printing of High Viscosity Metallic Pastes

open access: yesMetals, 2020
Laser-induced forward transfer (LIFT) technique has been used for printing a high viscosity (250 Pa·s) commercial silver paste with micron-size particles (1−4 µm).
David Munoz-Martin   +3 more
doaj   +1 more source

Genetic Diagnosis and Discovery Enabled by Large Language Models

open access: yesAdvanced Science, EarlyView.
We demonstrate that large language models (LLMs) can facilitate genetic diagnosis and discovery. LLMs were used to solve four types of genetic problems of sequentially increased complexity. An LLM‐based pipeline could analyze genetic variants in the genomic sequences of human hearing loss or rare genetic disease patients and assist in identifying ...
Tao Tu   +25 more
wiley   +1 more source

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