Results 361 to 370 of about 457,916 (395)
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Stability of aspartate aminotransferase and alanine aminotransferase activities.
The Journal of laboratory and clinical medicine, 1983Because there are conflicting data regarding the effect of different temperatures and durations of storage on the stability of the activities of aspartate aminotransferase (AST) and alanine aminotransferase (ALT), a new study has been conducted to re-examine this important issue.
Hyman J. Zimmerman +4 more
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Alanine Aminotransferase Levels in Blood Donors
Annals of Internal Medicine, 1987Excerpt To the editor: Friedman and coworkers (1) have addressed an issue of concern to blood bankers regarding the approach to the blood donor with isolated or intermittent elevations of alanine a...
John E. Fitzpatrick +2 more
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Alanine Aminotransferase and Posttransfusion Hepatitis
JAMA: The Journal of the American Medical Association, 1987To the Editor.— The American Red Cross is initiating the screening of donor blood for high alanine aminotransferase (ALT) levels to reduce the incidence of posttransfusion hepatitis. Non-A, non-B hepatitis, probably caused by several viruses, is the major cause of posttransfusion hepatitis. Thirty percent of patients with posttransfusion hepatitis are
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Alanine Aminotransferase and Aspartate Aminotransferase in Leishmania tarentolae1
The Journal of Protozoology, 1971SYNOPSIS. Culture stages (promastigotes) of Leishmania tarentolae were tested for alanine aminotransferase (E.C.2.6.1.2) and aspartate aminotransferase (E.C.2.6.1.1.). Neither enzyme was detected in crude cell extracts. After starch block electrophoresis, however, both transaminase activities were found in proteins migrating toward the anode. Only one
Stuart M. Krassner, Daryl S. Fair
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Development of an electrochemical immunosensor for alanine aminotransferase
Biosensors and Bioelectronics, 2003Alanine aminotransferase (ALT) has been regarded as one of the most sensitive indicators of hepatocellular damage. While ALT is widely used in the practice of medicine, few attempts have been made to develop biosensors applicable to the on-site diagnosis of liver diseases.
Eui Yul Choi +2 more
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Serum Alanine Aminotransferase and Seronegative Hepatitis
Annals of Internal Medicine, 1988Excerpt To the editor: Previous studies (1, 2) have established a direct relation between elevated alanine aminotransferase (ALT) levels in donor blood and the risk for post-transfusion hepatitis.
Peter J. Meier, Martin Schmid
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Radioisotopic assay of aspartate and alanine aminotransferase
Clinical Biochemistry, 1992The activities of aspartate and alanine aminotransferases in biological samples were assessed through a novel and sensitive procedure, based on the conversion of [U-14C]2-ketoglutarate to L-[U-14C]glutamate. In human plasma, the generation of L-[U-14C]glutamate was proportional to the volume of plasma (20-60 microL) and to the length of incubation (30 ...
Perales, Miguel Angel +2 more
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Alanine Aminotransferase in Clinical Practice
Archives of Internal Medicine, 1991Alanine aminotransferase is an enzyme produced mainly in the liver. When serum activity is measured, it provides a marker of hepatic disease. This review explores the biochemistry and laboratory analysis of alanine aminotransferase in terms of its significance in human health and disease.
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Alanine Aminotransferase in Clinical Practice
Archives of Internal Medicine, 1992To the Editor. — The thoughtful review by Sherman 1 provides a useful approach to the practicing physician. He makes the recommendation that elevations of alanine aminotransferase levels less than twofold not be pursued even if they persist for 6 weeks or more. Although this appears a useful strategy in general, some forms of liver disease may benefit
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Stability of serum alanine aminotransferase activity
Transfusion, 1987In this study the authors examine the effects of common storage and handling procedures on serum alanine aminotransferase (ALT) levels. Clotted blood samples from 14 subjects were centrifuged at 280 × g for 10 minutes. Serum was tested immediately for baseline ALT levels and aliquots were stored at 22, 4, −20, and −80 ° C. Additional serums were stored
R Y Dodd +3 more
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