Results 51 to 60 of about 2,251,716 (324)

Autophagy Activators Normalize Aberrant Tau Proteostasis and Rescue Synapses in Human Familial Alzheimer's Disease iPSC‐Derived Cortical Organoids

Advanced Science, EarlyView.
A new cerebrocortical organoid model using isogenic hiPSCs with familial Alzheimer's mutations recapitulates key AD features, including amyloid‐beta and phospho‐Tau aggregation, neuronal hyperexcitability, and synapse loss. Single‐cell RNA‐seq reveals aberrant pathways in excitatory and inhibitory neurons.
Sergio R. Labra, Jadon Compher, Akhil Prabhavalkar, Mireya Almaraz, Claudia Cedeño Kwong, Christine Baal, Maria Talantova, Nima Dolatabadi, Julian Piña‐Sanz, Yubo Wang, Leonard Yoon, Swagata Ghatak, Zi Gao, Yuting Zhang, Dorit Trudler, Lynee Massey, Wei Lin, Anthony Balistreri, Michael Bula, Nicholas J. Schork, Tony S. Mondala, Steven R. Head, Jeffery W. Kelly, Stuart A. Lipton   +23 more
wiley   +1 more source

Impact of Moisture Exposure on Thermal Stability and Safety of Solid‐State Batteries

Advanced Energy Materials, EarlyView.
Sulfide‐based solid‐state batteries (SSBs) hold significant potential for next‐generation energy storage, yet their practical deployment is hindered by the moisture sensitivity of sulfide solid electrolytes. This study examines how moisture exposure influences thermo‐electrochemical instability at the material and cell‐level, and underscores the ...
Md Toukir Hasan, Alvaro J. Miguel, Bairav S. Vishnugopi, Abhinanda Sengupta, Avijit Karmakar, Gordon H. Waller, Corey T. Love, Partha P. Mukherjee   +7 more
wiley   +1 more source

Copper Contact for Perovskite Solar Cells: Properties, Interfaces, and Scalable Integration

Advanced Energy and Sustainability Research, EarlyView.
Copper electrodes, as low‐cost, scalable contacts for perovskite solar cells, offer several advantages over precious metals such as Au and Ag, including performance, cost, deposition methods, and interfacial engineering. Copper (Cu) electrodes are increasingly considered practical, sustainable alternatives to noble‐metal contacts in perovskite solar ...
Shuwei Cao, Jianyong Han, Xiaohu Zhao, Yaming Yu, Peng Gao   +4 more
wiley   +1 more source

Alans and Germans in the Bosporan Kingdom in the second half of the 3rd century

Античная древность и средние века, 2018
According to antique authors, Alans from 1st century AD were neighbors of Asian part of the Kingdom of the Cimmerian Bosporus and wandered between the lower current of the Volga and Don rivers, and also in northern and east coast of the Azov Sea, up to ...
Alexander Aibabin
doaj   +1 more source

Artificial Intelligence for Bone: Theory, Methods, and Applications

Advanced Intelligent Discovery, EarlyView.
Advances in artificial intelligence (AI) offer the potential to improve bone research. The current review explores the contributions of AI to pathological study, biomarker discovery, drug design, and clinical diagnosis and prognosis of bone diseases. We envision that AI‐driven methodologies will enable identifying novel targets for drugs discovery. The
Dongfeng Yuan, Haicang Zhang, Liping Tong, Di Chen   +3 more
wiley   +1 more source

The Alans in Mongolia and China: the main written sources (1253–1811)

Золотоордынское обозрение
This paper is a source study review aimed at presenting the main information that details the history of the Alans’ service to the Mongols in Mongolia and China.
Kaziev E.V.
doaj   +1 more source

The Challenge of Handling Structured Missingness in Integrated Data Sources

Advanced Intelligent Discovery, EarlyView.
As data integration becomes ever more prevalent, a new research question that emerges is how to handle missing values that will inevitably arise in these large‐scale integrated databases? This missingness can be described as structured missingness, encompassing scenarios involving multivariate missingness mechanisms and deterministic, nonrandom ...
James Jackson, Marius Hofert, Eleni‐Rosalina Andrinopoulou, Niels Hagenbuch, Sarah McGough, Chris Harbron, Robin Mitra   +6 more
wiley   +1 more source

Ressenyes [PDF]

, 2007
Index de les obres ressenyades: J. LÓPEZ QUIROGA ; A. M. MARTÍNEZ TEJERA ; J. MORÍN DE PABLOS, (eds.) Gallia e Hispania en el contexto de la presencia «germánica» (ss.
Gibert Rebull, Jordi
core  

Confessions of a Poverty Researcher: My Journey Through the Foothills of Scholarship

Australian Journal of Social Issues, EarlyView.
ABSTRACT This paper describes the key events, experiences and ideas that influenced the author's career as a poverty researcher. He describes how his early disillusion with economics was replaced by a spark of interest in social issues and how his migration from the UK to Australia in the mid‐1970s provided the impetus to begin what became a lifetime ...
Peter Saunders
wiley   +1 more source

L'expedició dels khàzars : un paral·lel caucàsic d'Heròdot? [PDF]

, 1998
The first work of the collection known as the Georgian Chronicles (KÔartÔlis CÔxovreba), «The History of the Kings of Iberia» by Leonti Mroveli, contains an episode relating to a Khazar invasion of Transcaucasia in a remote past, some generations after ...
Alemany i Vilamajó, Agustí
core   +1 more source