Results 111 to 120 of about 609,297 (304)

Size‐Modulated Mesoderm‐Endoderm Divergence and Myocardial Cavitation in Micropatterned Cardioids

open access: yesAdvanced Science, EarlyView.
Micropatterned cardioids, CRISPR‐engineered reporter hiPSCs, deep‐tissue imaging, and single‐cell RNA sequencing are integrated to model mesoderm‐endoderm co‐development. Heart‐foregut crosstalk promotes single large cavitation inside cardioids, resembling early heart chamber formation. ABSTRACT The human heart, originating from the splanchnic mesoderm,
Plansky Hoang   +12 more
wiley   +1 more source

Alaska-Washington Trade Profile: Waterborne Commerce [PDF]

open access: yes, 1978
The overall purpose of this study was to establish a profile of Alaska-Washington waterborne movements, emphasizing commodity and port components that determine the needs of a physical distribution system.
Logsdon, Charles L., Thomas, Wayne C.
core  

2D Copper MOF Membranes with Precise Pores for Ionic Memory

open access: yesAdvanced Science, EarlyView.
 . ABSTRACT Biological ion channels play a critical role in the complex physiological processes of living organisms. Inspired by these natural systems, we demonstrate the fabrication of ultrathin 2D copper‐based metal‐organic framework (CuMOF) films and their application to mimic key functionalities of biological membranes. Using a liquid–air interface
Hiran Jyothilal   +9 more
wiley   +1 more source

Kids Count Alaska 2006/2007 [PDF]

open access: yes, 2008
About This Year’s Book Every year the Kids Count Alaska data book reports on how the children of Alaska are doing. But we also like to tell readers a bit more about life in Alaska, to help them understand the place Alaska’s children call home.
DeRoche, Patricia   +3 more
core  

Delivery of Pleckstrin‐Homology Domains Suppresses PI3K/Akt Signaling and Breast Cancer Metastasis

open access: yesAdvanced Science, EarlyView.
Current therapies curb tumor growth but not metastasis. Obscurin, a giant metastasis suppressor lost in breast cancer, restrains PI3K/Akt signaling but is impractical to restore. We deploy a mini‐obscurin, comprising the obscurin‐PH‐domain, which sequesters PI3K‐p85, potently suppressing invasion and metastasis.
Matthew Eason   +12 more
wiley   +1 more source

The American Frontier in the Works of Russian Historians: A Critical Review of Articles on Russian America Published in 2024

open access: yesЖурнал Фронтирных Исследований
This study is a critical review of ten scientific articles devoted to the Russian frontier in the northern part of the Pacific Ocean and the west coast of North America in the 18th–19th centuries, where Russian colonies were formed in Alaska and ...
Andrei V. Grinev
doaj   +1 more source

Circular 16 [PDF]

open access: yes, 1951
Edda, an introduction from Sweden, was recommended for the first tim e in 195 I for all barley-growing areas of Alaska. About 200 bushels of this new barley variety were available for distribution to Alaska growers in 195 I through the Alaska ...
Bensin, B.M., Litzenberger, S.C.
core  

Beyond Transconductance: Cell‐Polymer Coupling Determines Fidelity in Action Potential Recording via Electrolyte‐Gated Polymer Transistors

open access: yesAdvanced Science, EarlyView.
High electrical performance alone does not guarantee efficient bioelectronic signal transduction. Despite excellent mixed ionic‐electronic conduction, recordings from cardiomyocytes reveal that p(g2T‐TT)‐based OECTs predominantly transduce field potential FP‐like signals due to weak cell‐polymer coupling.
Giulia Zoe Zemignani   +10 more
wiley   +1 more source

Synchrotron XRF Imaging Reveals Manganese Accumulation in the Golgi and Post‐Synapses of Neurons and Enhanced Uptake in Astrocytes

open access: yesAdvanced Science, EarlyView.
Despite widespread exposure, the mechanisms of manganese neurotoxicity remain poorly understood. Using correlative cryogenic fluorescence and synchrotron X‐ray fluorescence imaging techniques, we show that the Golgi apparatus is the primary accumulation site for manganese in both neurons and astrocytes, and that manganese targets the neuronal ...
Ines Kelkoul   +12 more
wiley   +1 more source

利用导波震相分析阿拉斯加俯冲带东端Yakutat地体的洋壳结构特征

open access: yesDizhen xuebao
低速俯冲洋壳附近震源激发的部分地震波被困在低速层内以导波传播,弧前地震台站所记录的导波可用于洋壳结构成像。阿拉斯加俯冲带具有丰富的地震事件且布设了相对密集的永久性地震台站,为利用导波探测洋壳结构提供了天然试验场。本文对区域密集台站记录到的阿拉斯加俯冲带东端Yakutat地体两侧中源地震事件的导波震相传播特征进行了深入分析。结果显示:阿拉斯加俯冲带东端的Yakutat地体范围内,受低速俯冲洋壳影响的导波震相到时延迟随传播距离的增大而增加 ...
Xiaoyu Guan, Yuanze Zhou
doaj   +1 more source

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