Results 221 to 230 of about 179,880 (310)

Management of ring chromosome 20 syndrome: Narrative review and consensus recommendations

Epilepsia, EarlyView.
Abstract Ring chromosome 20 (ring 20) is a rare genetic condition usually presenting as developmental and epileptic encephalopathy. The disease is caused by fusion of the long and short arms of chromosome 20. Patients are symptomatic even if there is no loss of genetic material.
Asma Khamis, Emilia Ricci, Maria Paola Canevini, Lieven Lagae, Kentaro Tokumoto, Yushi Inoue, Tim Buckinx, Allison Watson, Kenneth A. Myers   +8 more
wiley   +1 more source

First European detection and genomic analysis of <i>Francisella tularensis</i> subsp. <i>tularensis</i> in a traveler returning from Canada. [PDF]

IDCases
Rutschmann O, Leuenberger D, Raemy S, Koller R, Baumann L, Paniga S, Jaton K, Metzger CMJA, Schmidt KM.   +8 more
europepmc   +1 more source

A first in disease trial of the safety, tolerability, and anti‐seizure effects of ES‐481 in drug‐resistant epilepsy

Epilepsia Open, EarlyView.
Abstract Objectives ES‐481 is a novel potent and selective antagonist of TARP‐y8‐dependent AMPA receptors. We aimed to assess the potential efficacy, safety and tolerability, and pharmacokinetics of different doses of ES‐481 as an add‐on anti‐seizure medication (ASM) in adults with drug‐resistant epilepsy (DRE). Methods This was a Phase 2A double‐blind,
Emma C. Foster, Lyn Millist, Jack Germaine, Stephanie Chamorro, Caitlin Roberts, John‐Paul Nicolo, Sean Hosking, Piero Perucca, Saul Mullen, Heather Robinson, Rebecca Wharrie, Brittany Walsh, David Reutens, Kimberley Irwin, Hao Zeng, Robert Niecestro, Terence J. O'Brien   +16 more
wiley   +1 more source

<i>Sarcocystis pinnipedi</i> predominates <i>Sarcocystis</i> spp. infections in free-ranging Alaskan marine mammals. [PDF]

Int J Parasitol Parasites Wildl
Chiu ES, Sinnott D, Stimmelmayr R, Rotstein D, Armién AG, Shapiro K.   +5 more
europepmc   +1 more source

Characteristics and long‐term outcomes of children with confirmed focal cortical dysplasia type 1 after epilepsy surgery: A population‐based study

Epilepsia Open, EarlyView.
Abstract Objective Focal cortical dysplasia type 1 (FCD1) is a rare and heterogeneous cause of drug‐resistant epilepsy (DRE) in children. Its clinical characteristics remain poorly understood, and surgical outcomes may be less favorable than in FCD2. We conducted a population‐based study to characterize the clinical presentation and long‐term seizure ...
Vincent Zheng, Päivi Koroknay‐Pál, Henri Lehtinen, Eija Gaily, Atte Karppinen, Anders Paetau, Olli Tynninen, Heta Leinonen, Aki Laakso, Eeva‐Liisa Metsähonkala   +9 more
wiley   +1 more source

Region- and season-specific exposure to lead in a common North American songbird. [PDF]

Ecotoxicology
Ohrberg ML, Becker DJ, Filippelli GM, Ketterson ED, Rader ST, Reed SM, Williams EJ, Jahn AE.   +7 more
europepmc   +1 more source

The 2025 Kamchatka Earthquake and Tsunami: Cascading Impacts and Risks to Japan

Earthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT On July 29th, 2025, a large earthquake (Mw 8.8) occurred near the Kamchatka Peninsula. This event caused a tsunami that reached Japan's Pacific coast, even though the source was far away. In this study, we analyze the characteristics of earthquakes and tsunamis and discuss how they relate to the recurrence possibility and risk in Japan.
Ampan Laosunthara, An‐Chi Cheng, Yo Fukushima, Yoshinori Shigihara, Natt Leelawat, Anawat Suppasri, Fumihiko Imamura   +6 more
wiley   +1 more source

Prevalence and Clinical Characteristics of Systemic Sclerosis in Alaska Native and American Indian Peoples in Alaska. [PDF]

ACR Open Rheumatol
Mehta VR, Holck P, Choromanski TL, Wilson A, Lee F, Ferucci ED.   +5 more
europepmc   +1 more source

Evaluation of the Adequacy of Design Specifications for Nonstructural Components in a Reticular Structure

Earthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT Nonstructural components (NSCs) installed in large‐span reticular structures were frequently severely damaged during earthquakes, even when the primary structure remained intact. Existing seismic design specifications for NSCs were predominantly developed for upright structures such as multi‐storey buildings and offer no guidance for reticular
Xudong Zhi, Fengze Li, Duozhi Wang, Nawawi Chouw, Rong Zhang, Bo Huang, Feng Fan   +6 more
wiley   +1 more source

Fragment-Based Online OzESI-MS, NMR, and Computational DP4+/DFT Approaches to the Characterization of the Putative Biosynthetic Lipid Precursor of Atkamine from Alaskan <i>Latrunculia</i> Sponges. [PDF]

ACS Omega
Benjamin MM, Dickinson CF, Wood JS, Williamson RT, Hanna GS, Alford AS, Stone RP, Hoff GR, Samala AR, Mulani FA, Zhang Q, Hamann MT.   +11 more
europepmc   +1 more source