Results 91 to 100 of about 36,880 (256)

Solid Polymeric Nanoparticles of Albendazole: Synthesis, Physico-Chemical Characterization and Biological Activity

Molecules, 2020
Albendazole is a benzimidazole derivative with documented antitumor activity and low toxicity to healthy cells. The major disadvantage in terms of clinical use is its low aqueous solubility which limits its bioavailability.
Roxana Racoviceanu, Cristina Trandafirescu, Mirela Voicu, Roxana Ghiulai, Florin Borcan, Cristina Dehelean, Claudia Watz, Zoltán Aigner, Rita Ambrus, Dorina Elena Coricovac, Denisa Cîrcioban, Alexandra Mioc, Camelia Alexandrina Szuhanek, Codruţa Şoica   +13 more
doaj   +1 more source

Prevalence of intestinal protozoa infection among school-aged children on Pemba Island, Tanzania, and effect of single-dose albendazole, nitazoxanide and albendazole-nitazoxanide. [PDF]

, 2013
Pathogenic intestinal protozoa infections are common in school-aged children in the developing world and they are frequently associated with malabsorption syndromes and gastrointestinal morbidity.
Albonico, Marco, Ali, Said M, Ame, Shaali M, Bogoch, Isaac I, Keiser, Jennifer, Marti, Hanspeter, Speich, Benjamin, Utzinger, Jürg   +7 more
core   +3 more sources

Hookworm Infection Mimicking Early Gastric Mucosal Carcinoma: Magnifying Endoscopy Findings in Two Cases

JGH Open, Volume 9, Issue 9, September 2025.
ABSTRACT Background Hookworms primarily parasitize in the intestinal tract, and the gastric involvement is extremely rare, which often leads to misdiagnosis. We present two cases of hookworm infection that mimicked early gastric carcinoma. Case Summary Two patients presented with clear boundaries gastric mucosa lesions exhibiting brownish discoloration,
Fengrui Zhang, Yan Tao, Junkun Niu
wiley   +1 more source

Understanding Drug Exposure and Trichuris trichiura Cure Rates: A Pharmacometric Approach for Albendazole-Ivermectin Co-medication in Tanzania and Côte d’Ivoire

Drugs in R&D
Background and Objective Trichuriasis caused by the human whipworm Trichuris trichiura poses a significant public health concern. Albendazole-ivermectin co-medication is currently the most effective treatment.
Veshni Pillay-Fuentes Lorente, Jacinta N. Nwogu-Attah, Britta Steffens, Dominic Bräm, Viviane Sprecher, Daniela Hofmann, Michael Buettcher, Goonaseelan Pillai, Samer Mouksassi, Jean Coulibaly, Marc Pfister, Jennifer Keiser   +11 more
doaj   +1 more source

Effect of nitazoxanide on albendazole pharmacokinetics in cerebrospinal fluid and plasma in rats

Saudi Pharmaceutical Journal, 2017
Background: Although albendazole is the drug-of-choice for the treatment of neurocysticercosis, its efficacy is limited due to its low bioavailability. An alternative for optimizing pharmacological treatment is through drug combinations. In vitro studies
María Isabel Ruiz-Olmedo, Iliana González-Hernández, Francisca Palomares-Alonso, Javier Franco-Pérez, María de Lourdes González F., Helgi Jung-Cook   +5 more
doaj   +1 more source

Dosing pole recommendations for lymphatic filariasis elimination: A height-weight quantile regression modeling approach [PDF]

, 2019
BACKGROUND: The World Health Organization (WHO) currently recommends height or age-based dosing as alternatives to weight-based dosing for mass drug administration lymphatic filariasis (LF) elimination programs.
Dubray, Christine, Fischer, Peter U, Goss, Charles W, Hardy, Myra, Jambulingam, Purushothaman, King, Christopher L, Laman, Moses, Lemoine, Jean Frantz, O\u27Brian, Katiuscia, Robinson, Leanne J, Samuela, Josaia, Schechtman, Kenneth B, Subramanian, Swaminathan, Supali, Taniawati, Weil, Gary J   +14 more
core   +2 more sources

Impact of anthelminthic treatment in pregnancy and childhood on immunisations, infections and eczema in childhood: a randomised controlled trial.

PLoS ONE, 2012
BackgroundHelminth infections may modulate immune responses to unrelated pathogens and allergens; these effects may commence prenatally. We addressed the hypothesis that anthelminthic treatment in pregnancy and early childhood would improve responses to ...
Juliet Ndibazza, Harriet Mpairwe, Emily L Webb, Patrice A Mawa, Margaret Nampijja, Lawrence Muhangi, Macklyn Kihembo, Swaib A Lule, Diana Rutebarika, Barbara Apule, Florence Akello, Hellen Akurut, Gloria Oduru, Peter Naniima, Dennison Kizito, Moses Kizza, Robert Kizindo, Robert Tweyongere, Katherine J Alcock, Moses Muwanga, Alison M Elliott   +20 more
doaj   +1 more source

Fatal pancytopenia due to albendazole treatment for strongyloidiasis

IDCases, 2018
We report 7 cases of strongyloidiasis that had occurred from 2016 through 2017 in a tertiary hospital of southern China. Three of the 7 patients (age 66–77) with farming exposure many years ago developed symptomatic infection while receiving ...
Fanfan Xing, Haiyan Ye, Jin Yang, Jasper Fuk-Woo Chan, Wai-Kay Seto, Pearl Ming-Chu Pai, Kwok-Yung Yuen, Derek Ling-Lung Hung   +7 more
doaj   +1 more source

Role of albendazole in the management of hydatid cyst liver

The Saudi Journal of Gastroenterology, 2011
Background/Aim: Hydatidosis has a worldwide distribution and the liver is the most common organ involved. Hydatid cysts of the liver can be managed either by nonoperative or operative methods.
Shams-Ul-Bari, Sajad Hussain Arif, Ajaz A Malik, Abdul Rouf Khaja, Tufale A Dass, Zahoor A Naikoo   +5 more
doaj   +1 more source

Predictors of Failure from Primary Therapy for Giardiasis in San Diego: A Single Institution Retrospective Review. [PDF]

, 2019
This study aimed to determine the presence of giardiasis among HIV patients in San Diego, the rate of failure of metronidazole treatment, and factors associated with treatment failure.
Debnath, Anjan, Morris, Sheldon R, Reed, Sharon L   +2 more
core   +1 more source