Results 51 to 60 of about 36,880 (256)

Isolated splenic cystic echinococcosis and albendazole hepatotoxicity

IDCases, 2022
Isolated splenic cystic echinococcosis is a rare condition. In Greece the number of cases has declined substantially in the last 20 years. The spleen is the second most common extrahepatic site of cystic echinococcosis.
Nikolaos Moussas, Sotirios Adamidis, Nikolaos Adamidis, Charalabos Stratopoulos, Panagiotis Gargalianos-Kakolyris   +4 more
doaj   +1 more source

Praziquantel coverage in schools and communities targeted for the elimination of urogenital schistosomiasis in Zanzibar: a cross-sectional survey [PDF]

, 2015
© 2015 Knopp et al. Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any ...
Ali, SM, Ame, SM, Blair, L, Fenwick, A, Juma, S, Khamis, IS, Knopp, S, Mohammed, KA, Muhsin, J, Person, B, Rabone, M, Rollinson, D   +11 more
core   +2 more sources

Targeting Multilayered Metabolic Networks in Brain Diseases: Emerging Perspectives on Nanodelivery Strategies

Advanced Science, EarlyView.
Brain diseases involve multilayered metabolic disruptions that reshape cellular interactions and microenvironments. This review outlines core metabolic features across disease states and presents emerging nanodelivery strategies as precision tools to reprogram pathological metabolism.
Jingyi Zhou, Chen Jiang
wiley   +1 more source

Comparison of albendazole cytotoxicity in terms of metabolite formation in four model systems

Journal of Veterinary Research, 2017
Introduction: Albendazole is used to treat endoparasitic diseases in animals and humans. After oral administration, it is quickly oxidised into its pharmacologically active metabolite albendazole sulfoxide and then to sulfone.
Radko Lidia, Minta Maria, Jedziniak Piotr, Stypuła-Trębas Sylwia   +3 more
doaj   +1 more source

Detection of enteric parasite DNA in household and bed dust samples: potential for infection transmission. [PDF]

, 2020
BACKGROUND: Enteric parasites are transmitted in households but few studies have sampled inside households for parasites and none have used sensitive molecular methods.
Calderón, E, Cooper, PJ, Garcia-Ramon, D, Lopez, A, Mejia, R, Seco-Hidalgo, V   +5 more
core   +1 more source

Critical Evaluation of Methods for the Identification of Aneugens

Environmental and Molecular Mutagenesis, EarlyView.
ABSTRACT The genotoxic potential of chemicals must be evaluated in regulatory safety assessment settings, including but not limited to, the development of new pharmaceuticals, industrial chemicals, food and cosmetic ingredients, and agrochemicals. Initial assessment of the chromosome‐damaging potential of chemicals is often conducted in mammalian cells
Xiaowen Sun, Stephen D. Dertinger, Azeddine Elhajouji, Daniel J. Roberts, Jan van Benthem, Maik Schuler, Shambhu Roy, Alexandra Taraboletti, Connie L. Chen   +8 more
wiley   +1 more source

Efficacy and safety of nitazoxanide, albendazole, and nitazoxanide-albendazole against Trichuris trichiura infection: a randomized controlled trial. [PDF]

PLoS Neglected Tropical Diseases, 2012
The currently used anthelmintic drugs, in single oral application, have low efficacy against Trichuris trichiura infection, and hence novel anthelmintic drugs are needed. Nitazoxanide has been suggested as potential drug candidate.The efficacy and safety
Benjamin Speich, Shaali M Ame, Said M Ali, Rainer Alles, Jan Hattendorf, Jürg Utzinger, Marco Albonico, Jennifer Keiser   +7 more
doaj   +1 more source

An Atypical Presentation of Cystic Echinococcosis [PDF]

, 2020
Cystic echinococcosis (CE) is an infection caused by the Echinococcus granulosus tapeworm. CE generally manifests in the liver, but it may present in any organ. These patients often first present to the emergency department.
Abou Asala, Elian D., Axelson, Daniel, Grahf, Daniel C., Tetali, Bhavana   +3 more
core  

FIGO good practice recommendations on anemia in pregnancy, to reduce the incidence and impact of postpartum hemorrhage (PPH)

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Anemia affects 32 million pregnant women globally, contributing annually to more than 115 000 maternal deaths and 591 000 perinatal deaths worldwide. Low‐ and middle‐income countries (LMICs) bear the highest burden of anemia in pregnancy, with nearly 50% of affected pregnant women. It is now 2025, which is WHO's target year for a 50% reduction
Akaninyene E. Ubom, Ferdousi Begum, Diana Ramasauskaite, Albaro J. Nieto‐Calvache, Monica Oguttu, Inês Nunes, Zechariah J. Malel, Jolly Beyeza‐Kashesya, Alison Wright, on behalf of the FIGO Committee on Childbirth and Postpartum Hemorrhage   +9 more
wiley   +1 more source

Exposure of Heligmosomoides polygyrus and Trichuris muris to albendazole, albendazole sulfoxide, mebendazole and oxantel pamoate in vitro and in vivo to elucidate the pathway of drug entry into these gastrointestinal nematodes

International Journal for Parasitology: Drugs and Drug Resistance, 2017
Millions of people are treated with anthelmintics to control soil-transmitted helminth infections; yet, drug distribution in the plasma and gastrointestinal tract compartments and the pathway of drug uptake into gastrointestinal nematodes responsible for
Noemi Cowan, Charles Meier, Anna Neodo, Jennifer Keiser   +3 more
doaj   +1 more source