Results 211 to 220 of about 246,176 (312)

Vaporized cannabis versus placebo for acute migraine: A randomized, double‐blind, placebo‐controlled crossover trial

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective To assess the efficacy of cannabis for the treatment of acute migraine. Background Preclinical and retrospective studies suggest cannabinoids may be effective in migraine treatment. However, there have been no randomized clinical trials examining the efficacy of cannabinoids for acute migraine.
Nathaniel M. Schuster   +6 more
wiley   +1 more source

Making sense of TILs: recommendations for morphological assessment of tumour‐infiltrating lymphocytes in gastro‐oesophageal carcinoma

open access: yesHistopathology, EarlyView.
This review examines the role of tumour‐infiltrating lymphocytes (TILs) in gastro‐oesophageal carcinoma (GEC), focusing on their composition, clinical relevance and therapeutic utility. It proposes a framework for standardised evaluation and reporting of TILs, addressing GEC‐specific pathology challenges to support the widespread use and validation of ...
Ylva A Weeda   +38 more
wiley   +1 more source

Older Age Is Associated With Long‐Term Retention in Buprenorphine Treatment for Opioid Use Disorder

open access: yesJournal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Opioid use disorder (OUD) among older adults is a fast‐growing public health problem. However, little is known about treatment outcomes among older adults in office‐based buprenorphine programs. Thus, our objective was to examine how age is associated with buprenorphine treatment outcomes among adults with OUD who initiate ...
Justina L. Groeger   +11 more
wiley   +1 more source

Once‐Nightly Sodium Oxybate Meets American Academy of Sleep Medicine Criteria for Treatment of Narcolepsy

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Data from the REST‐ON trial were not available before the 2021 American Academy of Sleep Medicine (AASM) clinical practice guideline update, which included a literature review through August 2020. This post hoc analysis from REST‐ON assessed participants who achieved clinically significant improvements on individual AASM clinical significance ...
Luis E. Ortiz   +7 more
wiley   +1 more source

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