Results 1 to 10 of about 126,056 (371)

Estimated Prevalence and Testing for Albuminuria in US Adults at Risk for Chronic Kidney Disease [PDF]

JAMA Network Open, 2023
Key Points Question Among at-risk patients with hypertension or diabetes, what is the prevalence of albuminuria that is undetected? Findings In this cohort study of 192 108 adults with hypertension or diabetes having at least 2 outpatient health care ...
Chi D. Chu, Fang Xia, Yuxian Du, Rakesh Singh, D. Tuot, J. A. Lamprea-Montealegre, Ralph Gualtieri, Nick Liao, S. Kong, T. Williamson, M. Shlipak, M. Estrella   +11 more
semanticscholar   +2 more sources

Albuminuria-Lowering Effect of Dapagliflozin, Eplerenone, and Their Combination in Patients with Chronic Kidney Disease: A Randomized Crossover Clinical Trial

Journal of the American Society of Nephrology, 2022
Significance Statement In this randomized crossover clinical trial in patients with CKD with and without type 2 diabetes, we assessed the albuminuria-lowering effect of the sodium glucose co-transporter 2 (SGLT2) inhibitor dapagliflozin and ...
M. Provenzano, M. J. Puchades, C. Garofalo, N. Jongs, L. D’Marco, M. Andreucci, L. De Nicola, J. Górriz, Hiddo J. L. Heerspink   +8 more
semanticscholar   +3 more sources

Association between adiposity indices and incident albuminuria: Results from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) [PDF]

BMC Nephrology
Background Albuminuria is an early indicator of kidney damage, and obesity is one of its main risk factors. Increased adiposity has been shown to be associated with albuminuria.
Wagner do Nascimento Carvalho, Gustavo Velasquez-Melendez, Alexandra Dias Moreira, Maria del Carmen Bisi Molina, Luana Giatti, Sandhi M. Barreto   +5 more
doaj   +2 more sources

Albuminuria: An Underappreciated Risk Factor for Cardiovascular Disease

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
: Albuminuria, an established biomarker of the progression of chronic kidney disease, is also recognized as a biomarker for the risk of cardiovascular disease.
Joshua I Barzilay, Youssef M. K. Farag, Jeffrey Durthaler   +2 more
doaj   +2 more sources

Renal effects and associated outcomes during angiotensin-neprilysin inhibition in heart failure [PDF]

, 2018
Objectives: The purpose of this study was to evaluate the renal effects of sacubitril/valsartan in patients with heart failure and reduced ejection fraction.
Claggett, Brian, Damman, Kevin, Desai, Akshay S., Gori, Mauro, Jhund, Pardeep S., Lefkowitz, Martin P., McMurray, John J.V., Packer, Milton, Prescott, Margaret F., Rouleau, Jean L., Senni, Michele, Shi, Victor C., Solomon, Scott D., Swedberg, Karl, Zile, Michael R.   +14 more
core   +17 more sources

Estimated Glomerular Filtration Rate, Albuminuria, and Adverse Outcomes: An Individual-Participant Data Meta-Analysis.

Journal of the American Medical Association (JAMA), 2023
Importance Chronic kidney disease (low estimated glomerular filtration rate [eGFR] or albuminuria) affects approximately 14% of adults in the US. Objective To evaluate associations of lower eGFR based on creatinine alone, lower eGFR based on creatinine
Morgan E. Grams, J. Coresh, K. Matsushita, S. Ballew, Y. Sang, Aditya L. Surapaneni, N. Alencar de Pinho, A. Anderson, L. Appel, J. Ärnlöv, Fereidoun Azizi, N. Bansal, Samira Bell, H. Bilo, Nigel J Brunskill, J. Carrero, Steve Chadban, J. Chalmers, Jing Chen, Elizabeth L. Ciemins, Massimo Cirillo, Natalie Ebert, Marie Evans, Alejandro Ferreiro, Edouard L. Fu, M. Fukagawa, Jamie Green, Orlando M. Gutiérrez, W. Herrington, Shih-Jen Hwang, L. Inker, Kunitoshi Iseki, T. Jafar, S. Jassal, Vivekanand Jha, A. Kadota, R. Katz, A. Köttgen, T. Konta, F. Kronenberg, Brian J Lee, Jennifer S. Lees, Adeera Levin, H. Looker, R. Major, C. Melzer Cohen, M. Mieno, M. Miyazaki, O. Moranne, I. Muraki, D. Naimark, D. Nitsch, Wonsuk Oh, M. Pena, Tanjala S. Purnell, C. Sabanayagam, M. Satoh, S. Sawhney, E. Schaeffner, B. Schöttker, Jenny I. Shen, M. Shlipak, Smeeta Sinha, B. Stengel, K. Sumida, M. Tonelli, J. Valdivielso, A. V. van Zuilen, F. Visseren, Angela Yee-Moon Wang, Chi-Pang Wen, D. C. Wheeler, H. Yatsuya, Kunihiro Yamagata, Jae won Yang, Ann Young, Haitao Zhang, Luxia Zhang, A. Levey, R. Gansevoort   +79 more
semanticscholar   +1 more source

The relationship between triglyceride-glucose index and albuminuria in United States adults

Frontiers in Endocrinology, 2023
Purpose Triglyceride-glucose (TyG) index is a simple and reliable indicator of metabolic dysfunction. We aimed to investigate a possible relationship between TyG index and albuminuria in the United States adult population.
Zhaoxiang Wang, Han Qian, Shao Zhong, Tian-Miao Gu, Mengjiao Xu, Qichao Yang   +5 more
semanticscholar   +1 more source

Albuminuria Screening in People With Type 2 Diabetes in a Managed Care Organization

AJPM Focus, 2023
Introduction: Albuminuria—an increased amount of urine albumin, in milligrams, adjusted for grams of urine creatinine—is an early marker of diabetic kidney disease.
Farrah Keong, MPH, Jennifer Gander, PhD, Daniel Wilson, MD, Jeffrey Durthaler, DPh, Belkis Pimentel, MD, Joshua I. Barzilay, MD   +5 more
doaj   +1 more source

Mineralocorticoid receptor antagonism in diabetes reduces albuminuria by preserving the glomerular endothelial glycocalyx

JCI Insight, 2023
The glomerular endothelial glycocalyx (GEnGlx) forms the first part of the glomerular filtration barrier. Previously, we showed that mineralocorticoid receptor (MR) activation caused GEnGlx damage and albuminuria.
Michael Crompton, J. Ferguson, R. Ramnath, K. L. Onions, A. S. Ogier, M. Gamez, C. Down, L. Skinner, K. Wong, L. Dixon, J. Sutak, S. Harper, P. Pontrelli, L. Gesualdo, H. Heerspink, R. Toto, G. Welsh, R. Foster, S. Satchell, M. Butler   +19 more
semanticscholar   +1 more source

Prevention of cardiorenal damage: importance of albuminuria.

European Heart Journal, 2022
Chronic kidney disease (CKD) is projected to become a leading global cause of death by 2040, and its early detection is critical for effective and timely management.
L. Ruilope, A. Ortiz, A. Lucía, Blanca Miranda, G. Álvarez-Llamas, M. Barderas, M. Volpe, G. Ruiz‐Hurtado, B. Pitt   +8 more
semanticscholar   +1 more source