Results 1 to 10 of about 100,735 (284)

Association between adiposity indices and incident albuminuria: Results from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) [PDF]

BMC Nephrology
Background Albuminuria is an early indicator of kidney damage, and obesity is one of its main risk factors. Increased adiposity has been shown to be associated with albuminuria.
Wagner do Nascimento Carvalho, Gustavo Velasquez-Melendez, Alexandra Dias Moreira, Maria del Carmen Bisi Molina, Luana Giatti, Sandhi M. Barreto   +5 more
doaj   +2 more sources

TLR-mediated albuminuria needs TNFα-mediated cooperativity between TLRs present in hematopoietic tissues and CD80 present on non-hematopoietic tissues in mice [PDF]

Disease Models & Mechanisms, 2016
Transient albuminuria induced by pathogen-associated molecular patterns (PAMPs) in mice through engagement of Toll-like receptors (TLRs) is widely studied as a partial model for some forms of human nephrotic syndrome (NS).
Nidhi Jain, Bhavya Khullar, Neelam Oswal, Balaji Banoth, Prashant Joshi, Balachandran Ravindran, Subrat Panda, Soumen Basak, Anna George, Satyajit Rath, Vineeta Bal, Shailaja Sopory   +11 more
doaj   +2 more sources

Estimated pulse wave velocity as a potential predictor of albuminuria in hypertension [PDF]

Frontiers in Medicine
BackgroundIncreased arterial stiffness is an important marker of target organ damage in hypertension. Estimated pulse wave velocity (ePWV) is a noninvasive assessment of arterial stiffness based on blood pressure and age calculations, but its association
Xianghui Zeng, Chunqing Xiao, Wenqing Xu, Qingfeng Zeng, Jincheng Wu, Jianping Luo   +5 more
doaj   +2 more sources

Renal effects and associated outcomes during angiotensin-neprilysin inhibition in heart failure [PDF]

, 2018
Objectives: The purpose of this study was to evaluate the renal effects of sacubitril/valsartan in patients with heart failure and reduced ejection fraction.
Claggett, Brian, Damman, Kevin, Desai, Akshay S., Gori, Mauro, Jhund, Pardeep S., Lefkowitz, Martin P., McMurray, John J.V., Packer, Milton, Prescott, Margaret F., Rouleau, Jean L., Senni, Michele, Shi, Victor C., Solomon, Scott D., Swedberg, Karl, Zile, Michael R.   +14 more
core   +17 more sources

Albuminuria Screening in People With Type 2 Diabetes in a Managed Care Organization

AJPM Focus, 2023
Introduction: Albuminuria—an increased amount of urine albumin, in milligrams, adjusted for grams of urine creatinine—is an early marker of diabetic kidney disease.
Farrah Keong, MPH, Jennifer Gander, PhD, Daniel Wilson, MD, Jeffrey Durthaler, DPh, Belkis Pimentel, MD, Joshua I. Barzilay, MD   +5 more
doaj   +1 more source

Activation of Rac-1 and RhoA contributes to podocyte injury in chronic kidney disease [PDF]

, 2013
Rho-family GTPases like RhoA and Rac-1 are potent regulators of cellular signaling that control gene expression, migration and inflammation. Activation of Rho-GTPases has been linked to podocyte dysfunction, a feature of chronic kidney diseases (CKD). We
Amann, Kerstin, Babelova, Andrea, Brandes, Ralf Peter Louis, Daniel, Christoph, Fork, Christian, Jansen, Felix, Jung, Oliver, Löhn, Matthias, Pavenstädt, Hermann, Plettenburg, Oliver, Ruetten, Hartmut, Sander, Kerstin, Schäfer, Liliana, Stark, Holger   +13 more
core   +15 more sources

Fractional Flow Reserve Derived from Computer Tomography in Asymptomatic Patients with Type 2 Diabetes and Albuminuria without Significant Coronary Artery Stenosis—A Surrogate for Coronary Microvascular Dysfunction?

Hearts, 2021
Background: Type 2 diabetes mellitus (T2D) patients with albuminuria have coronary microvascular dysfunction (CMD). Fractional flow reserve assessed by coronary computed tomography angiography (FFRct) is dependent on the structure and function of the ...
Jess Lambrechtsen, Laurits Juhl Heinsen, Johanna Larsson, Gokulan Pararajasingam, Kenneth Egstrup   +4 more
doaj   +1 more source

High Prevalence and Low Awareness of Albuminuria in the Community Setting in the KDSAP

Kidney International Reports, 2020
Introduction: Albuminuria is a sign of kidney disease and associated with adverse outcomes. However, most individuals with albuminuria are unaware of it.
Min Zhuo, Ming-Yan Jiang, Rui Song, Suraj Sarvode Mothi, Sirine Bellou, Laura C. Polding, Jiahua Li, Andrew Cho, Li-Li Hsiao   +8 more
doaj   +1 more source

Association between albuminuria and retinal microvascular dysfunction in type 2 diabetes with and without hypertension

Diabetes Epidemiology and Management, 2023
Background: Studies assessing the concordance of albuminuria and retinal microvascular dysfunction (RMD) in type 2 diabetes (T2D) have yielded inconsistent results. Similar to ethnicity, hypertension may be a potential explanatory variable.
Charles Antwi-Boasiako, Kwaku Amponsah Obeng, Kwesi Nyan Amissah-Arthur, Latif Musah, Benjamin Abaidoo, Henry Wedoi Awuviri, Joseph Agyapong Abbey, Pelagia Awula, Ruth Korkor Tei, Charles Agyemang, Albert.G.B. Amoah, Charles F. Hayfron-Benjamin   +11 more
doaj   +1 more source

Central obesity and albuminuria: both cross-sectional and longitudinal studies in Chinese. [PDF]

PLoS ONE, 2012
Albuminuria is recognized as a marker of vascular dysfunction. Central obesity increases the risk of cardiovascular disease. Little is known about the association between albuminuria and central obesity in Chinese.
Wen-Yuan Lin, F Xavier Pi-Sunyer, Chiu-Shong Liu, Chia-Ing Li, Lance E Davidson, Tsai-Chung Li, Cheng-Chieh Lin   +6 more
doaj   +1 more source