Differential renal effects of candesartan at high-and ultra-high doses in diabetic mice: potential role of ACE2/AT2R/Mas [PDF]
, 2016 High doses of Ang II receptor (AT1R) blockers (ARBs) are renoprotective in diabetes. Underlying mechanisms remain unclear. We evaluated whether high/ultra-high doses of candesartan (ARB) up-regulate angiotensin-converting enzyme 2 (ACE2)/Ang II type 2 ...
Antunes, Tayze +10 more
core +1 more source
The correlation between albuminuria and cystatin C in the assessment of the kidney function in patients with type 2 diabetes mellitus [PDF]
Scripta Medica, 2015 Introduction: Cystatin C has shown a better correlation with albuminuria in relation to creatinine. It filters in glomeruli, reabsorbs in tubules, and does not go back into circulation, which makes it a reliable parameter for the assessment of kidney ...
Risović Ivona +2 more
doaj
Long-term renal function and hypertension in adult survivors of childhood sarcoma [PDF]
, 2018 Aim: Little data is available on long-term renal impairment in survivors from childhood sarcoma. We investigated the prevalence of renal impairment and hypertension after very long-term follow-up in survivors who reached adulthood after treatment for ...
Andreoli, Gianmarco +6 more
core +1 more source
Determination of Albuminuria as a Component of Screening for Type 2 Diabetes Mellitus
Mìžnarodnij Endokrinologìčnij Žurnal, 2015 Objective of the Study. Determining the prevalence of albuminuria in patients with diagnosed diabetes mellitus type 2 (DM2). Materials and Methods of the Study.
L.O. Prystupiuk
doaj +1 more source
Correlates of calcaneal quantitative ultrasound parameters in patients with diabetes: the study on the assessment of determinants of muscle and bone strength abnormalities in diabetes [PDF]
, 2017 OBJECTIVE: Quantitative ultrasound (QUS) provides an estimate of bone mineral density (BMD) and also evaluates bone quality, which has been related to increased fracture risk in people with diabetes.
Alessi, Elena +11 more
core +2 more sources
Indonesian Journal of Rheumatology, 2018 Background Gout arthritis associates with many comorbodities such as hyperuricemia, hypertension, hyperglycemia, obesity, and dyslipidemia, which are also factors for the development of/or predisposition factors of chronic kidney diseases (CKD ...
Jeffrey Christian Mahardhika +1 more
doaj +1 more source
Albuminuria during treatment with angiotensin type II receptor blocker is a predictor for GFR decline among non-diabetic hypertensive CKD patients. [PDF]
PLoS ONE, 2018 BACKGROUND:Albuminuria is a predictor of disease progression in patients with chronic kidney disease (CKD). However, the ability of proteinuria parameters measured at various time periods to predict renal outcomes is unclear.
Mi-Yeon Yu +7 more
doaj +1 more source
Proteomic prediction and Renin angiotensin aldosterone system Inhibition prevention Of early diabetic nephRopathy in TYpe 2 diabetic patients with normoalbuminuria (PRIORITY): essential study design and rationale of a randomised clinical multicentre trial [PDF]
, 2016 Introduction: Diabetes mellitus affects 9% of the European population and accounts for 15% of healthcare expenditure, in particular, due to excess costs related to complications.
Beige, Joachim +14 more
core +4 more sources
The impact of nonalcoholic fatty liver disease on renal function in children with overweight/obesity [PDF]
, 2016 The association between nonalcoholic fatty liver disease (NAFLD) and chronic kidney disease has attracted interest and attention over recent years. However, no data are available in children.
Andreoli, Gian Marco +6 more
core +6 more sources
Long-term glycemic variability and risk of adverse outcomes: a systematic review and meta-analysis [PDF]
, 2015 OBJECTIVE: Glycemic variability is emerging as a measure of glycemic control, which may be a reliable predictor of complications. This systematic review and meta-analysis evaluates the association between HbA1c variability and micro- and macrovascular ...
Catherine Gorst +18 more
core +1 more source