Results 91 to 100 of about 121,309 (370)
Microphysiological Systems for Comorbidity Studies: Chronic Kidney Disease and Osteoarthritis
Advanced Healthcare Materials, EarlyView.This review highlights the potential of organ‐on‐a‐chip systems for studying comorbidities, using chronic kidney disease (CKD) and osteoarthritis (OA) as examples. It summarizes recent advances in kidney‐on‐a‐chip and joint‐on‐a‐chip models and discusses their current and potential application in investigating CKD, OA, and CKD‐OA comorbidity, aiming to
Mingying Han +7 more
wiley +1 more source
Disease Models & Mechanisms, 2016 Transient albuminuria induced by pathogen-associated molecular patterns (PAMPs) in mice through engagement of Toll-like receptors (TLRs) is widely studied as a partial model for some forms of human nephrotic syndrome (NS).
Nidhi Jain +11 more
doaj +1 more source
EXPERIMENTAL ALBUMINURIA IN THE RABBIT [PDF]
Archives of Pediatrics & Adolescent Medicine, 1921 It is a well recognized fact that the excretion of albumin in the urine occurs in circulatory disturbances of the kidneys. As the kidney is very sensitive to circulatory disorders, albuminuria may occur (except in nephritis) either because of local congestion of the veins and capillaries, or because of anemic infarct of the kidney. It may also occur in
Kumataro Gondo, Hideo Saito
openaire +2 more sources
Deletion of diacylglycerol-responsive TRPC genes attenuates diabetic nephropathy by inhibiting activation of the TGFβ1 signaling pathway [PDF]
, 2017 TRPC6 plays a critical role in proteinuric kidney diseases, and TRPC3 is involved in tubulointerstitialdamage and renal fibrosis in obstructed kidneys. Podocyte loss is a characteristic event in diabetic nephropathy(DN).
Birnbaumer, Lutz +5 more
core
Urinary excretion of RAS, BMP, and WNT pathway components in diabetic kidney disease. [PDF]
, 2014 The renin-angiotensin system (RAS), bone morphogenetic protein (BMP), and WNT pathways are involved in pathogenesis of diabetic kidney disease (DKD).
Afkarian, Maryam +5 more
core +1 more source
Advanced Healthcare Materials, EarlyView.An ex vivo glomerular filtration barrier is engineered using electrospun, biomimetic membranes seeded with human glomerular cells. The model supports fenestrated endothelium and podocyte foot processes under flow, mimics size‐selective filtration, and enables disease modeling with hiPSC‐derived podocytes, offering a powerful platform for studying ...
Camilla Mussoni +8 more
wiley +1 more source
HU Revista, 2019 Introdução: A obesidade é um dos fatores mais importantes para explicar o aumento incidência das Doenças Cardiovasculares (DCV). Dentre os múltiplos fatores de risco para estas doenças, a albuminúria é dos mais importantes.
Danielle Braga +6 more
doaj +1 more source
Hyperfiltration during early childhood precedes albuminuria in pediatric sickle cell nephropathy
American journal of hematology/oncology, 2019 In patients with diabetes mellitus, hyperfiltration precedes the development of albuminuria. Pediatric sickle cell anemia (SCA) patients have a high prevalence of hyperfiltration and albuminuria during early childhood and adolescence.
J. Lebensburger +6 more
semanticscholar +1 more source
Electrochemical Biosensor for Rapid Detection of Acute Rejection in Kidney Transplants
Advanced Healthcare Materials, EarlyView.A low‐cost, rapid electrochemical immunosensor coated with a novel antifouling nanocomposite enables single‐step, dual‐biomarker profiling directly from unprocessed urine. Application in a clinical study shows accurate discrimination of acute rejection in kidney transplants from other acute kidney injuries via machine learning.
Rohit Gupta +9 more
wiley +1 more source