FREQUENCY OF MICROALBUMINURIA IN THE MIDDLE AGE AND OLDER POPULATION OF PESHAWAR CITY
Objectives: To determine the frequency of micro albuminuria in the middle age and older population of both genders in Peshawar city of Pakistan. Study Design: Random control study. Place and Duration of Study: This study was carried out from Jan
Mohammad Yousaf+4 more
doaj
Deletion of diacylglycerol-responsive TRPC genes attenuates diabetic nephropathy by inhibiting activation of the TGFβ1 signaling pathway [PDF]
TRPC6 plays a critical role in proteinuric kidney diseases, and TRPC3 is involved in tubulointerstitialdamage and renal fibrosis in obstructed kidneys. Podocyte loss is a characteristic event in diabetic nephropathy(DN).
Birnbaumer, Lutz+5 more
core
Long-term glycemic variability and risk of adverse outcomes: a systematic review and meta-analysis [PDF]
OBJECTIVE: Glycemic variability is emerging as a measure of glycemic control, which may be a reliable predictor of complications. This systematic review and meta-analysis evaluates the association between HbA1c variability and micro- and macrovascular ...
Catherine Gorst+18 more
core +1 more source
Role of STING Deficiency in Amelioration of Mouse Models of Lupus and Atherosclerosis
Objective Systemic lupus erythematosus (SLE) is a systemic autoimmune syndrome characterized by autoreactive responses to nucleic acids, dysregulation of the type I interferon (IFN‐I) pathway, and accelerated atherosclerosis. The stimulator of IFN genes (STING), a cytosolic DNA sensor, has pathogenic implications in various inflammatory diseases ...
Yudong Liu+10 more
wiley +1 more source
High prevalence of albuminuria among adult males living with HIV in Botswana
Chronic HIV disease is associated with a fivefold increase in albuminuria outside of sub-Saharan Africa. However, very little is known about albuminuria risk among people living with HIV (PLWH) in sub-Saharan Africa.
Mosepele Mosepele+10 more
doaj +1 more source
Prevalencia de Micro albuminuria en pacientes hipertensos no diabéticos
Introducción: Se ha demostrado que la presencia de micro albuminuria puede reflejar el desarrollo de enfermedad cardiovascular en pacientes con diabetes mellitus, este fenómeno también se ha observado en pacientes no diabéticos.
Sofia Roldán, Clara Chang
doaj +1 more source
Randomized multicentre pilot study of sacubitril/valsartan versus irbesartan in patients with chronic kidney disease: United Kingdom Heart and Renal Protection (HARP)- III—rationale, trial design and baseline data [PDF]
BACKGROUND: Patients with chronic kidney disease (CKD) are at risk of progression to end-stage renal disease and cardiovascular disease. Data from other populations and animal experiments suggest that neprilysin inhibition (which augments the ...
Baigent, C.+23 more
core +1 more source
Objective We aimed to study the disease course, outcomes, and predictors of outcome in pediatric‐onset antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV) affecting the kidneys. Methods Patients eligible for this study had a diagnosis of granulomatosis with polyangiitis (GPA), microscopic polyangiitis, or ANCA‐positive pauci‐immune ...
Kirandeep K. Toor+39 more
wiley +1 more source
A gene variant in CERS2 is associated with rate of increase in albuminuria in patients with diabetes from ONTARGET and TRANSCEND. [PDF]
Although albuminuria and subsequent advanced stage chronic kidney disease are common among patients with diabetes, the rate of increase in albuminuria varies among patients.
Dov Shiffman+7 more
doaj +1 more source