Results 91 to 100 of about 125,121 (369)

Kidney disease progression and all-cause mortality across estimated glomerular filtration rate and albuminuria categories among patients with vs. without type 2 diabetes

open access: yesBMC Nephrology, 2020
Background Studies of progression of kidney dysfunction typically focus on renal replacement therapy or percentage decline in estimated glomerular filtration rate (eGFR) as outcomes.
G. Nichols   +5 more
semanticscholar   +1 more source

SETDB2 Mitigates Podocyte Dysfunction in Diabetic Kidney Disease Through Epigenetic Silencing of SMAD3

open access: yesAdvanced Science, EarlyView.
SETDB2 epigenetically represses Smad3 transcription by increasing H3K9me3 enrichment at its promoter, thereby mitigating podocyte dysfunction in DKD. The transcription factor TCF21 binds directly to the Setdb2 promoter and enhances its expression in podocytes. Abstract Podocyte dysfunction represents both an early pathological hallmark and a key driver
Lanfang Li   +14 more
wiley   +1 more source

Effect of Albuminuria on the State of Plasma Hemostasis in Patients with Essential Hypertension

open access: yesPočki, 2016
In recent decades, numerous scientific works are devoted to the study of the clinical and prognostic significance of albuminuria, methods of its detection, as well as treatment measures aimed at controlling this pathological condition.
A.I. Pastushyna, O.M. Plenova
doaj   +1 more source

Correlates of calcaneal quantitative ultrasound parameters in patients with diabetes: the study on the assessment of determinants of muscle and bone strength abnormalities in diabetes [PDF]

open access: yes, 2017
OBJECTIVE: Quantitative ultrasound (QUS) provides an estimate of bone mineral density (BMD) and also evaluates bone quality, which has been related to increased fracture risk in people with diabetes.
Alessi, Elena   +11 more
core   +2 more sources

Hyperfiltration during early childhood precedes albuminuria in pediatric sickle cell nephropathy

open access: yesAmerican journal of hematology/oncology, 2019
In patients with diabetes mellitus, hyperfiltration precedes the development of albuminuria. Pediatric sickle cell anemia (SCA) patients have a high prevalence of hyperfiltration and albuminuria during early childhood and adolescence.
J. Lebensburger   +6 more
semanticscholar   +1 more source

Effectiveness of Pre‐Transplant Dual GLP‐1 Receptor Agonist and SGLT2 Inhibitor Therapy on All‐Cause Mortality in Organ Transplantation Candidates with Obesity and Type 2 Diabetes: a Target‐Trial Emulation

open access: yesAdvanced Science, EarlyView.
This target trial emulation in solid organ transplant candidates with obesity and type 2 diabetes evaluates whether pre‐transplant dual therapy with GLP‐1 receptor agonists plus SGLT2 inhibitors is associated with post‐transplant mortality and kidney graft outcomes compared with monotherapy or usual care, using multinational electronic health records ...
Yu‐Nan Huang   +7 more
wiley   +1 more source

High prevalence of albuminuria among adult males living with HIV in Botswana

open access: yesScientific Reports
Chronic HIV disease is associated with a fivefold increase in albuminuria outside of sub-Saharan Africa. However, very little is known about albuminuria risk among people living with HIV (PLWH) in sub-Saharan Africa.
Mosepele Mosepele   +10 more
doaj   +1 more source

Avaliação dos níveis de albuminúria em adultos obesos e sua associação com marcadores de risco cardiovascular.

open access: yesHU Revista, 2019
Introdução: A obesidade é um dos fatores mais importantes para explicar o aumento incidência das Doenças Cardiovasculares (DCV). Dentre os múltiplos fatores de risco para estas doenças, a albuminúria é dos mais importantes.
Danielle Braga   +6 more
doaj   +1 more source

A discrete cluster of urinary biomarkers discriminates between active systemic lupus erythematosus patients with and without glomerulonephritis. [PDF]

open access: yes, 2016
BackgroundManagement of lupus nephritis (LN) would be greatly aided by the discovery of biomarkers that accurately reflect changes in disease activity.
Avila-Casado, Carmen   +10 more
core   +3 more sources

Impact of Renin‐Angiotensin System Inhibitors on Renal Function During Temporary Ileostomy Period in Rectal Cancer Patients: A Retrospective Cohort Study

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This retrospective study explored the potential impact of renin–angiotensin system inhibitors (RASIs) on renal function during the ileostomy period in patients undergoing rectal cancer surgery. RASI use was associated with early postoperative renal impairment, and relatively slow recovery of renal function was observed until stoma closure.
Yusaku Shogen   +6 more
wiley   +1 more source

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