Results 91 to 100 of about 123,506 (328)

Kidney disease progression and all-cause mortality across estimated glomerular filtration rate and albuminuria categories among patients with vs. without type 2 diabetes

BMC Nephrology, 2020
Background Studies of progression of kidney dysfunction typically focus on renal replacement therapy or percentage decline in estimated glomerular filtration rate (eGFR) as outcomes.
G. Nichols, Anouk Déruaz-Luyet, K. Brodovicz, T. Kimes, A. Rosales, Sibylle J. Hauske   +5 more
semanticscholar   +1 more source

Expert Perspective: Diagnosis and Treatment of Castleman Disease

Arthritis &Rheumatology, EarlyView.
Castleman disease (CD) is a major diagnostic challenge for rheumatologists. Unicentric CD (UCD) involves one enlarged lymph node region, whereas multicentric CD (MCD) involves multiple enlarged lymph node regions. Both UCD and MCD may exhibit a wide range of symptoms that overlap with other immune‐mediated conditions.
Luke Y. C. Chen, Lu Zhang, David C. Fajgenbaum   +2 more
wiley   +1 more source

FREQUENCY OF MICROALBUMINURIA IN THE MIDDLE AGE AND OLDER POPULATION OF PESHAWAR CITY

Pakistan Armed Forces Medical Journal, 2018
Objectives: To determine the frequency of micro albuminuria in the middle age and older population of both genders in Peshawar city of Pakistan. Study Design: Random control study. Place and Duration of Study: This study was carried out from Jan
Mohammad Yousaf, Muzammil Arshad, Kehkasha Sabir, Ibrahim ., Razaullah .   +4 more
doaj  

Epidermal Interferon kappa drives cutaneous lupus‐like lesions, photosensitivity and systemic autoimmunity in vivo

Arthritis &Rheumatology, Accepted Article.
Objective Keratinocyte‐derived interferon kappa (IFN‐κ) is chronically overexpressed in human non‐lesional systemic lupus erythematosus (SLE) skin. Recent evidence suggests that epidermal signals instruct the immune system in SLE, but whether epidermal IFN‐κ alone is sufficient to drive lupus phenotypes has not been investigated.
Benjamin Klein, Deborah J. Colesa, Yiqing Gao, Patrick A. O'Brien, Lin Zhang, Lori Lowe, Kelsey E. McNeely, Nguyen Thi Kim Nguyen, Svenja Henning, Mehrnaz Gharaee‐Kermani, Jeffrey B. Hodgin, Jacob W. S. Martens, Johann E. Gudjonsson, Celine C. Berthier, J. Michelle Kahlenberg   +14 more
wiley   +1 more source

High prevalence of albuminuria among adult males living with HIV in Botswana

Scientific Reports
Chronic HIV disease is associated with a fivefold increase in albuminuria outside of sub-Saharan Africa. However, very little is known about albuminuria risk among people living with HIV (PLWH) in sub-Saharan Africa.
Mosepele Mosepele, Ponego Ponatshego, Kesaobaka Molebatsi, Christopher Williams, Lucky Mokgatlhe, Shahin Lockman, Nabila Youssouf, Robert Gross, Joseph Jarvis, Duolao Wang, Shabbar Jaffar   +10 more
doaj   +1 more source

Deletion of diacylglycerol-responsive TRPC genes attenuates diabetic nephropathy by inhibiting activation of the TGFβ1 signaling pathway [PDF]

, 2017
TRPC6 plays a critical role in proteinuric kidney diseases, and TRPC3 is involved in tubulointerstitialdamage and renal fibrosis in obstructed kidneys. Podocyte loss is a characteristic event in diabetic nephropathy(DN).
Birnbaumer, Lutz, He, Xiju, Li, Shoutian, Liao, Yanhong, Liu, Benju, Xu, Benke   +5 more
core  

The efficacy of Telitacicept in Childhood‐onset Systemic Lupus Erythematosus: a prospective multi‐center cohort study with IPTW‐adjusted comparison to a historical control group treated with Belimumab

Arthritis &Rheumatology, Accepted Article.
Objective The therapeutic effects of Telitacicept combined with standard of care (SoC) in childhood‐onset systemic lupus erythematosus (cSLE) remain unclear. This study aims to evaluate its efficacy in comparison with Belimumab combined with SoC. Methods We performed a prospective cohort study across 7 tertiary hospitals in China, enrolling patients ...
Chong Luo, Shu Su, Jingyue Liu, Junyu Lin, Jin Song, Zongwen Chen, Yuanyuan Peng, Lijun Jiang, Meng Jia, Li Wang, Xinhui Jiang, Wei Zhang, Zanhua Rong, Bo zhao, Yajun Wang, Xuemei Tang   +15 more
wiley   +1 more source

Albuminuria in patients with chronic obstructive pulmonary disease: a cross-sectional study in an African patient cohort

BMC Pulmonary Medicine, 2018
Background Cardiovascular disease (CVD) is remarkably frequent in patients with chronic obstructive pulmonary disease (COPD). Albuminuria is a marker of vascular endothelial dysfunction and predictor of CVD events.
Festo K. Shayo, Janet Lutale
doaj   +1 more source

Timing of bariatric surgery in people with obesity and diabetes [PDF]

, 2015
The use of bariatric surgery in the clinical management of type 2 diabetes in severely obese subjects has been included in the clinical practice recommendations released by the most influential diabetologic associations.
Busetto, Luca
core   +1 more source

Finerenone Attenuates Endothelial Dysfunction and Albuminuria in a Chronic Kidney Disease Model by a Reduction in Oxidative Stress

Frontiers in Pharmacology, 2018
Albuminuria is an early marker of renovascular damage associated to an increase in oxidative stress. The Munich Wistar Frömter (MWF) rat is a model of chronic kidney disease (CKD), which exhibits endothelial dysfunction associated to low nitric oxide ...
R. González-Blázquez, B. Somoza, M. Gil-Ortega, M. Martín Ramos, David Ramiro-Cortijo, E. Vega-Martín, A. Schulz, L. Ruilope, P. Kolkhof, R. Kreutz, M. Fernández-Alfonso   +10 more
semanticscholar   +1 more source