Results 111 to 120 of about 120,733 (325)
Correlation Between HbA1c and Albuminuria in Type 2 Diabetes Mellitus
Majalah Kedokteran Bandung, 2020 In patients with type 2 diabetes mellitus (Type 2 DM), glycemic control plays an essential role in reducing macro- and microvascular complications. The earliest marker for diabetic nephropathy is the presence of albuminuria.
Jesika Merlin, Pusparini Pusparini
doaj +1 more source
Elevated cystatin-C concentration is associated with progression to prediabetes: the Western New York Study [PDF]
, 2007 OBJECTIVE – We conducted a nested case-control investigation to examine if elevated baseline concentrations of cystatin-C predicted progression from normoglycaemia to prediabetes over 6 years of follow-up from the Western New York Health Study. RESEARCH
Dmochowski, Jacek +5 more
core +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT RASopathies are clinically overlapping neurodevelopmental syndromes resulting from germline mutations in genes involved in the rat sarcoma/mitogen‐activated protein kinases (RAS/MAPK) pathway. Historically, RASopathies have been described by clinical phenotypes, such as Noonan syndrome and Neurofibromatosis type I.
Anastasia‐Vasiliki Madenidou +6 more
wiley +1 more source
Diabetes, obesity and metabolism, 2017 The MARLINA‐T2D study (ClinicalTrials.gov, NCT01792518) was designed to investigate the glycaemic and renal effects of linagliptin added to standard‐of‐care in individuals with type 2 diabetes and albuminuria.
P. Groop +15 more
semanticscholar +1 more source
Animal Models and Experimental Medicine, EarlyView.The current study characterized temporal changes in glomerular gene expression, pathology, and biomarkers in a mouse model of hypertension‐accelerated diabetic kidney disease (DKD). Progressive albuminuria and glomerulosclerosis were paralleled by dynamic transcriptomic changes associated withmetabolic dysfunction, extracellular matrix remodeling, and ...
Adam B. Marstrand‐Jørgensen +8 more
wiley +1 more source
Challenges of modeling pristane‐induced lupus in non‐human primates
Animal Models and Experimental Medicine, EarlyView.Systemic lupus erythematosus (SLE) in cynomolgus monkeys was modeled by two intraperitoneal injections of pristane at a dose of 3.5 mL/kg, administered at weeks 1 and 23. Serum samples from all monkeys that received pristane tested positive for antinuclear antibodies.
Elena Vladimirovna Vinogradova +5 more
wiley +1 more source
Journal of the American Society of Nephrology, 2006 Proteins in the urine are classically associated with renal disease. In the past, it was considered to be the result of renal damage, in particular a filtration defect. Later, the concept of proteinuria being a marker, a mediator, or even a cause of renal damage was entertained.
openaire +3 more sources
BMC Nephrology, 2018 BackgroundAlbuminuria, elevated serum creatinine and low estimated glomerular filtration rate (eGFR) are pivotal indicators of kidney decline. Yet, it is uncertain if these and emerging biomarkers such as uric acid represent independent predictors of ...
Keith C. Norris +4 more
semanticscholar +1 more source
Mucosal‐Associated Invariant T Cells in Rheumatic Diseases
Arthritis &Rheumatology, EarlyView.Mucosal‐associated invariant T (MAIT) cells are innate‐like T cells defined by their semi‐invariant T cell receptor and restriction by the major histocompatibility complex class I–related molecule (MR1). These cells are primarily activated by microbial‐derived metabolites presented by MR1 or by cytokines.
Manon Lesturgie‐Talarek +7 more
wiley +1 more source
Association between inflammation indicators and albuminuria in US adults: a cross-sectional study
Scientific ReportsPrevious studies have established associations between the C-reactive protein to lymphocyte ratio (CLR), inflammatory load index (IBI), and neutrophil to albumin ratio (NAR) with various conditions.
Xinyu Ma +4 more
doaj +1 more source