Results 131 to 140 of about 120,733 (325)

Temporal prevalence and prognostic impact of diabetes mellitus and albuminuria in heart failure with preserved ejection fraction

Cardiovascular Diabetology
Background Most patients with heart failure with preserved ejection fraction (HFpEF) have a metabolic phenotype in which comorbidities including diabetes mellitus play an important role.
Nousjka P. A. Vranken, Xinyu Li, Heleen Bouman, Sanne G. J. Mourmans, Anouk Achten, Arantxa Barandiarán Aizpurua, Hans-Peter Brunner-La Rocca, Christian Knackstedt, Vanessa P. M. van Empel, Jerremy Weerts   +9 more
doaj   +1 more source

Renal Function, Albuminuria, and the Risk of Cardiovascular Events After Kidney Transplantation

Transplantation Direct, 2018
Background. The risk of mortality and graft loss is higher in kidney transplant recipients with reduced estimated glomerular filtration rate (eGFR) and albuminuria.
Ngan N. Lam, MD, MSc, Scott Klarenbach, MD, MSc, Robert R. Quinn, MD, PhD, Brenda Hemmelgarn, MD, PhD, Marcello Tonelli, MD, SM, Feng Ye, MSc, Pietro Ravani, MD, PhD, Aminu K. Bello, MD, PhD, Daniel C. Brennan, MD, Krista L. Lentine, MD, PhD   +9 more
doaj   +1 more source

Research-based versus clinical serum creatinine measurements and the association of acute kidney injury with subsequent kidney function: findings from the Chronic Renal Insufficiency Cohort study. [PDF]

, 2020
Background:Observational studies relying on clinically obtained data have shown that acute kidney injury (AKI) is linked to accelerated chronic kidney disease (CKD) progression.
Anderson, Amanda H, Appel, Lawrence J, Chen, Jing, Feldman, Harold I, Go, Alan S, He, Jiang, Hsu, Chi-yuan, Hsu, Raymond K, Kusek, John W, Lash, James P, Liu, Kathleen D, McCulloch, Charles E, Navaneethan, Sankar D, Porter, Anna C, Rahman, Mahboob, Rao, Panduranga S, Tan, Thida C, Townsend, Raymond R, Wilson, F Perry, Xie, Dawei, Yang, Jingrong, Zhang, Xiaoming   +21 more
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Finerenone Attenuates Endothelial Dysfunction and Albuminuria in a Chronic Kidney Disease Model by a Reduction in Oxidative Stress

Frontiers in Pharmacology, 2018
Albuminuria is an early marker of renovascular damage associated to an increase in oxidative stress. The Munich Wistar Frömter (MWF) rat is a model of chronic kidney disease (CKD), which exhibits endothelial dysfunction associated to low nitric oxide ...
R. González-Blázquez, B. Somoza, M. Gil-Ortega, M. Martín Ramos, David Ramiro-Cortijo, E. Vega-Martín, A. Schulz, L. Ruilope, P. Kolkhof, R. Kreutz, M. Fernández-Alfonso   +10 more
semanticscholar   +1 more source

Nationwide temporal trends in adverse pregnancy outcomes and treatments in systemic lupus erythematosus pregnancy over two decades in Sweden

Arthritis &Rheumatology, Accepted Article.
Objective This nationwide descriptive study examined temporal trends in adverse pregnancy outcomes (APOs) and treatments in systemic lupus erythematosus (SLE) pregnancies in Sweden over 2003‐2022. Methods Using nationwide Swedish registers, we identified 1,417 pregnancies of women with prevalent SLE and delivery dates in 2003‐2022, and matched them to ...
Ngoc V. Nguyen, Anna Sandström, Annica Dominicus, Elisabet Svenungsson, Karin Hellgren, Julia F. Simard, Elizabeth V. Arkema   +6 more
wiley   +1 more source

5‐Methylcytosine Analysis of miRNAs in Minimal Change Disease

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Minimal change disease (MCD) is a glomerular disorder, which is the most common cause of nephrotic syndrome in children. Additionally, the prevalence of MCD in adults has been increasing in recent years. During protein synthesis, noncoding RNAs can be regulated through a variety of modifications, which helps preserve biological diversity and ...
Huiyi Zeng, Dandan Li, Yunyi Li, Chen Yun, Xinzhou Zhang, Wenyu Gong, Mengyun Xiao, Haitao Li, Zhipeng Zeng, Ruqi Tan, Yishen Yang, Shaodong Luan, Yong Dai, Lianghong Yin, Donge Tang   +14 more
wiley   +1 more source

Effects of Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers on All-Cause Mortality and Renal Outcomes in Patients with Diabetes and Albuminuria: a Systematic Review and Meta-Analysis

Kidney & Blood Pressure Research, 2018
Background/Aims: Whether angiotensin-converting enzyme (ACE) inhibitors or angiotensin II receptor blockers (ARB) could benefit patients with diabetes and albuminuria remains controversial.
Kanran Wang, Jinbo Hu, Ting Luo, Yue Wang, Shumin Yang, Hua Qing, Q. Cheng, Qifu Li   +7 more
semanticscholar   +1 more source

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

Estimated pulse wave velocity as a potential predictor of albuminuria in hypertension

Frontiers in Medicine
BackgroundIncreased arterial stiffness is an important marker of target organ damage in hypertension. Estimated pulse wave velocity (ePWV) is a noninvasive assessment of arterial stiffness based on blood pressure and age calculations, but its association
Xianghui Zeng, Chunqing Xiao, Wenqing Xu, Qingfeng Zeng, Jincheng Wu, Jianping Luo   +5 more
doaj   +1 more source

Tubulointerstitial injury and proximal tubule albumin transport in early diabetic nephropathy induced by type 1 diabetes mellitus [PDF]

, 2017
A decrease in the tubular expression of albumin endocytic transporters megalin and cubilin has been associated with diabetic nephropathy (DN), but there are no comprehensive studies to date relating early tubulointerstitial injury and the effect of the ...
Bahamonde, Javiera, Ezquer, Fernando, Ezquer, Marcelo, Giraud Billoud, Maximiliano German   +3 more
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