Results 21 to 30 of about 125,121 (369)

Making an impact on kidney disease in people with type 2 diabetes: the importance of screening for albuminuria

BMJ Open Diabetes Research & Care, 2022
Albuminuria is useful for early screening and diagnosis of kidney impairment, especially in people with pre-diabetes or type 2 diabetes (T2D), which is the leading cause of chronic kidney disease (CKD) and end-stage kidney disease (ESKD), associated with
J. McGill, H. Haller, P. Roy-Chaudhury, A. Cherrington, T. Wada, C. Wanner, L. Ji, P. Rossing   +7 more
semanticscholar   +1 more source

The Effect of Dapagliflozin on Albuminuria in DECLARE-TIMI 58

Diabetes Care, 2021
OBJECTIVE Sodium–glucose cotransporter 2 inhibitors (SGLT2i) improve albuminuria in patients with high cardiorenal risk. We report albuminuria change in the Dapagliflozin Effect on Cardiovascular Events (DECLARE-TIMI 58) cardiovascular outcome trial ...
Ofri Mosenzon, S. Wiviott, Hiddo J. L. Heerspink, J. Dwyer, A. Cahn, Erica L. Goodrich, Aliza Rozenberg, Meir Schechter, Ilan Yanuv, S. Murphy, Thomas A. Zelniker, I. Gause-Nilsson, A. Langkilde, M. Fredriksson, P. Johansson, Deepak L. Bhatt, Lawrence A Leiter, D. McGuire, John P H Wilding, M. Sabatine, I. Raz   +20 more
semanticscholar   +1 more source

Predictors of progression in albuminuria in the general population: results from the PREVEND cohort. [PDF]

PLoS ONE, 2013
BACKGROUND: Urinary albumin excretion is known to be independently associated with progression of renal and cardiovascular disease. The aim of this study was to identify predictors for progression in albuminuria in the general population.
Lieneke Scheven, Nynke Halbesma, Paul E de Jong, Dick de Zeeuw, Stephan J L Bakker, Ron T Gansevoort   +5 more
doaj   +1 more source

Large-scale albuminuria screen for nephropathy models in chemically induced mouse mutants [PDF]

, 2005
Background/Aim: Phenotype-driven screening of a great pool of randomly mutant mice and subsequent selection of animals showing symptoms equivalent to human kidney diseases may result in the generation of novel suitable models for the study of the ...
Aigner, B., de Angelis, M. H., Klempt, M., Rathkolb, B., Tran, T. V., Wanke, R., Wolf, E.   +6 more
core   +1 more source

Association between urinary sodium, creatinine, albumin, and long term survival in chronic kidney disease [PDF]

, 2014
Dietary sodium intake is associated with hypertension and cardiovascular risk in the general population. In patients with chronic kidney disease, sodium intake has been associated with progressive renal disease, but not independently of proteinuria.
Fox, Jonathan G., Freel, E. Marie, Jardine, Alan G., Mark, Patrick, McQuarrie, Emily P., Taylor, Alison H., Traynor, Jamie P.   +6 more
core   +1 more source

Diabetic kidney disease. new clinical and therapeutic issues. Joint position statement of the Italian Diabetes Society and the Italian Society of Nephrology on "the natural history of diabetic kidney disease and treatment of hyperglycemia in patients with type 2 diabetes and impaired renal function" [PDF]

, 2019
Recent epidemiological studies have disclosed heterogeneity in diabetic kidney disease (DKD). In addition to the classical albuminuric phenotype, two new phenotypes have emerged, i.e., “nonalbuminuric renal impairment” and “progressive renal decline ...
Barutta, Federica, De Nicola, Luca, Di Paolo, Salvatore, Gesualdo, Loreto, Natali, Andrea, Penno, Giuseppe, Pugliese, Giuseppe, Reboldi, Gianpaolo   +7 more
core   +1 more source

Multiomics signatures of type 1 diabetes with and without albuminuria

Frontiers in Endocrinology, 2022
Aims/hypothesisTo identify novel pathophysiological signatures of longstanding type 1 diabetes (T1D) with and without albuminuria we investigated the gut microbiome and blood metabolome in individuals with T1D and healthy controls (HC).
Marc Clos-Garcia, Marc Clos-Garcia, Tarunveer S. Ahluwalia, Tarunveer S. Ahluwalia, Signe A. Winther, Peter Henriksen, Mina Ali, Yong Fan, Evelina Stankevic, Liwei Lyu, Josef K. Vogt, Josef K. Vogt, Torben Hansen, Cristina Legido-Quigley, Peter Rossing, Peter Rossing, Oluf Pedersen, Oluf Pedersen   +17 more
doaj   +1 more source

Baseline characteristics and enrichment results from the SONAR trial [PDF]

, 2018
Aim: The SONAR trial uses an enrichment design based on the individual response to the selective endothelin receptor antagonist atrasentan on efficacy (the degree of the individual response in the urinary albumin‐to‐creatinine ratio [UACR]) and safety/
Andress, Dennis L., Bakris, George, Brennan, John J., Correa-Rotter, Ricardo, de Zeeuw, Dick, Heerspink, Hiddo J.L., Hou, Fan Fan, Kitzman, Dalane W., Kohan, Donald, Makino, Hirofumi, McMurray, John, Parving, Hans-Henrik, Perkovic, Vlado, Tobe, Sheldon, Wigderson, Melissa, Yi, Tingting   +15 more
core   +3 more sources

Prevalence of Hypertension and Albuminuria in Pediatric Type 2 Diabetes

JAMA Network Open, 2021
Key Points Question What is the prevalence of hypertension and albuminuria in children and adolescents with type 2 diabetes? Findings This systematic review and meta-analysis of 60 studies found that 25% of children and adolescents with type 2 diabetes ...
Milena Cioana, Jiawen Deng, Maggie Hou, Ajantha Nadarajah, Yuan Qiu, Sondra Chen, Angélica Rivas, L. Banfield, Rahul Chanchlani, A. Dart, B. Wicklow, Haifa Alfaraidi, Ahlam Alotaibi, L. Thabane, M. C. Samaan   +14 more
semanticscholar   +1 more source

Long-term renal function and hypertension in adult survivors of childhood sarcoma [PDF]

, 2018
Aim: Little data is available on long-term renal impairment in survivors from childhood sarcoma. We investigated the prevalence of renal impairment and hypertension after very long-term follow-up in survivors who reached adulthood after treatment for ...
Andreoli, Gianmarco, Bonci, Enea, Celani, Camilla, Marrucci, Oriana, Pedetti, Valeria, Schiavetti, Amalia, Varrasso, Giulia   +6 more
core   +1 more source