Results 21 to 30 of about 87,895 (325)

Multiomics signatures of type 1 diabetes with and without albuminuria

Frontiers in Endocrinology, 2022
Aims/hypothesisTo identify novel pathophysiological signatures of longstanding type 1 diabetes (T1D) with and without albuminuria we investigated the gut microbiome and blood metabolome in individuals with T1D and healthy controls (HC).
Marc Clos-Garcia, Marc Clos-Garcia, Tarunveer S. Ahluwalia, Tarunveer S. Ahluwalia, Signe A. Winther, Peter Henriksen, Mina Ali, Yong Fan, Evelina Stankevic, Liwei Lyu, Josef K. Vogt, Josef K. Vogt, Torben Hansen, Cristina Legido-Quigley, Peter Rossing, Peter Rossing, Oluf Pedersen, Oluf Pedersen   +17 more
doaj   +1 more source

Diabetic kidney disease. new clinical and therapeutic issues. Joint position statement of the Italian Diabetes Society and the Italian Society of Nephrology on "the natural history of diabetic kidney disease and treatment of hyperglycemia in patients with type 2 diabetes and impaired renal function" [PDF]

, 2019
Recent epidemiological studies have disclosed heterogeneity in diabetic kidney disease (DKD). In addition to the classical albuminuric phenotype, two new phenotypes have emerged, i.e., “nonalbuminuric renal impairment” and “progressive renal decline ...
Barutta, Federica, De Nicola, Luca, Di Paolo, Salvatore, Gesualdo, Loreto, Natali, Andrea, Penno, Giuseppe, Pugliese, Giuseppe, Reboldi, Gianpaolo   +7 more
core   +1 more source

Clinical and laboratory profile and outcomes of hospitalized COVID‐19 patients with type 2 diabetes mellitus in Ghana – A single‐center study

Endocrinology, Diabetes &Metabolism, Volume 6, Issue 1, January 2023., 2023
This study describes the clinical and laboratory profile and outcomes of hospitalized COVID‐19 patients with type 2 diabetes mellitus (DM) in Ghana. Out of 175 patients (mean age 55.9+/−18.3 years) 64 (36.6%) had DM. Compared to non‐diabetics, DM patients were older (61.1? 12.8 vs. 53.0?
Yasmine Oladele Hardy, Elena Libhaber, Emmanuel Ofori, Divine Aseye Yao Amenuke, Samuel Amoabeng Kontoh, James Amoah Dankwah, Rita Larsen‐Reindorf, Caleb Otu‐Ansah, Kojo Hutton‐Mensah, Ebenezer Dadson, Sheila Adamu, Kofi Akyerekoh, Fred Stephen Sarfo, Bernard Nkum   +13 more
wiley   +1 more source

The bidirectional association between depressive symptoms, assessed by the HADS, and albuminuria–A longitudinal population-based cohort study with repeated measures from the HUNT2 and HUNT3 Study

PLoS ONE, 2022
Background Both albuminuria and depression are associated with cardiovascular disease, reflecting low-grade systemic inflammation and endothelial dysfunction.
Lise Tuset Gustad, Anna Marie Holand, Torfinn Hynnekleiv, Ottar Bjerkeset, Michael Berk, Solfrid Romundstad   +5 more
doaj   +2 more sources

Association between urinary sodium, creatinine, albumin, and long term survival in chronic kidney disease [PDF]

, 2014
Dietary sodium intake is associated with hypertension and cardiovascular risk in the general population. In patients with chronic kidney disease, sodium intake has been associated with progressive renal disease, but not independently of proteinuria.
Fox, Jonathan G., Freel, E. Marie, Jardine, Alan G., Mark, Patrick, McQuarrie, Emily P., Taylor, Alison H., Traynor, Jamie P.   +6 more
core   +1 more source

Predictors of progression in albuminuria in the general population: results from the PREVEND cohort. [PDF]

PLoS ONE, 2013
BACKGROUND: Urinary albumin excretion is known to be independently associated with progression of renal and cardiovascular disease. The aim of this study was to identify predictors for progression in albuminuria in the general population.
Lieneke Scheven, Nynke Halbesma, Paul E de Jong, Dick de Zeeuw, Stephan J L Bakker, Ron T Gansevoort   +5 more
doaj   +1 more source

Liraglutide and renal outcomes in type 2 diabetes [PDF]

, 2017
In a randomized, controlled trial that compared liraglutide, a glucagon-like peptide 1 analogue, with placebo in patients with type 2 diabetes and high cardiovascular risk who were receiving usual care, we found that liraglutide resulted in lower risks ...
Brown-Frandsen, Kirstine, Buse, John B., Mann, Johannes F. E, Maranghi, M., Marso, Steven P, Poulter, Neil R, Rasmussen, Søren, Tornøe, Karen, Zinman, Bernard, Ørsted, David D   +9 more
core   +2 more sources

Anatomical and functional remodeling of left ventricle in patients with primary aldosteronism and concomitant albuminuria

Therapeutic Advances in Chronic Disease, 2023
Background: Primary aldosteronism (PA) is the leading cause of secondary hypertension globally and is associated with adverse cardiovascular outcomes. However, the cardiac impact of concomitant albuminuria remains unknown.
Ting-Wei Kao, Xue-Ming Wu, Che-Wei Liao, Cheng-Hsuan Tsai, Zheng-Wei Chen, Yi-Yao Chang, Bo-Ching Lee, Yu-Wei Chiu, Tai-Shuan Lai, Vin-Cent Wu, Yen-Hung Lin, Chi-Sheng Hung,   +12 more
doaj   +1 more source

Tissue lipidomic profiling supports a mechanistic role of the prostaglandin E2 pathway for albuminuria development in glomerular hyperfiltration

Frontiers in Network Physiology, 2023
Background: Glomerular hyperfiltration (GH) is an important mechanism in the development of albuminuria in hypertension. The Munich Wistar Frömter (MWF) rat is a non-diabetic model of chronic kidney disease (CKD) with GH due to inherited low nephron ...
Debora Kaiser-Graf, Angela Schulz, Eva Mangelsen, Michael Rothe, Juliane Bolbrinker, Reinhold Kreutz   +5 more
doaj   +1 more source

MicroRNA-184 is a downstream effector of albuminuria driving renal fibrosis in rats with diabetic nephropathy [PDF]

, 2017
Renal fibrosis is a common complication of diabetic nephropathy and is a major cause of end-stage renal disease. Despite the suggested link between renal fibrosis and microRNA (miRNA) dysregulation in diabetic nephropathy, the identification of the ...
Benigni, Ariela, Locatelli, Monica, Macconi, Daniela, Mestdagh, Pieter, Remuzzi, Giuseppe, Rottoli, Daniela, Rudnicki, Michael, Tomasoni, Susanna, Trionfini, Piera, Vandesompele, Jo, Zanchi, Cristina, Zoja, Carlamaria   +11 more
core   +2 more sources