Results 51 to 60 of about 85,863 (235)

Population pharmacokinetic modelling of prednisolone in systemic lupus erythematosus patients: Analysis of exposure and disease activity

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Prednisone is a widely used glucocorticoid in the treatment of lupus, although its dosing is often determined empirically. Prednisolone, the active metabolite of prednisone, is found in its free form in the serum. The goal of this study was to develop a population pharmacokinetic model in patients with systemic lupus erythematosus (SLE ...
Naïm Bouazza   +26 more
wiley   +1 more source

KAJIAN EKSPRESI TGF-ββββ1, MMP-9, KOLAGEN TIPE-1, KOLAGEN TIPE-IV, GLOMERULOSKLEROSIS, INTERSTISIAL FIBROSIS, ALBUMINURIA PADA KEJADIAN NEFROTOKSIK DOXORUBICIN DAN NEFROPROTEKTIF PENTOXIFYLLIN DENGAN HEWAN COBA MENCIT GALUR SWISS JANTAN [PDF]

open access: yes, 2010
Pemakaian Doxorubicin (DXR) dalam pengobatan kanker semakin meningkat, dengan meningkatnya morbiditas kanker. Efek nefrotoksik dari DXR masih menjadi masalah.
Purwanto, Bambang
core   +1 more source

An open‐label, single‐arm, multicenter, phase II trial of bireociclib as monotherapy for heavily pretreated HR‐positive, HER2‐negative advanced breast cancer patients: BRIGHT‐1 trial

open access: yesCancer Communications, EarlyView.
Abstract Background Bireociclib (XZP‐3287) is a novel selective cyclin‐dependent kinase 4 and 6 (CDK4/6) inhibitor, with a favorable safety profile demonstrated in preclinical and phase I studies. BRIGHT‐1 aimed to further explore the efficacy and safety of bireociclib monotherapy in patients with locally advanced, recurrent or metastatic, hormone ...
Jiayu Wang   +18 more
wiley   +1 more source

Correlates of calcaneal quantitative ultrasound parameters in patients with diabetes: the study on the assessment of determinants of muscle and bone strength abnormalities in diabetes [PDF]

open access: yes, 2017
OBJECTIVE: Quantitative ultrasound (QUS) provides an estimate of bone mineral density (BMD) and also evaluates bone quality, which has been related to increased fracture risk in people with diabetes.
Alessi, Elena   +11 more
core   +2 more sources

Albuminuria and heart failure: is it an albuminuria or the hypertension? [PDF]

open access: yesEuropean Heart Journal, 2007
Ingelsson et al. 1 elegantly emphasized albuminuria as a risk factor for heart failure in elderly hypertensive men and present thought-provoking speculative mechanisms. However, the association between albuminuria and heart failure was seen in untreated hypertensive men compared to treated hypertension, suggesting that treated hypertensive men had ...
openaire   +2 more sources

Detection of Fast Decliner of Diabetic Kidney Disease Using Chiral Amino Acid Profiling: A Pilot Study

open access: yesChemistry &Biodiversity, EarlyView.
We examined D‐amino acids in diabetic kidney disease (DKD). Among D‐amino acids, blood D‐serine was identified as a biomarker of DKD, and we found that short‐term change in blood D‐serine showed higher value in fast decliners in DKD patients, which meant the prognostic value of blood D‐serine in DKD.
Yosuke Hirakawa   +7 more
wiley   +1 more source

Puerperal Albuminuria [PDF]

open access: yesThe Boston Medical and Surgical Journal, 1882
n ...
openaire   +2 more sources

Contemporary Perspectives on Chronic Renal Disorders

open access: yesChronic Diseases and Translational Medicine, EarlyView.
ABSTRACT The prevalence of renal diseases and its associated burden on healthcare have tremendously risen in the past few years. From simple markers assessing kidney function, current renal research delves into understanding the diseases at the cellular and molecular levels and not just at treating, but at improving quality of life, arresting ...
Deenadhayalan Ashok   +5 more
wiley   +1 more source

Urinary proteomics for prediction of mortality in patients with type 2 diabetes and microalbuminuria [PDF]

open access: yes, 2018
Background: The urinary proteomic classifier CKD273 has shown promise for prediction of progressive diabetic nephropathy (DN). Whether it is also a determinant of mortality and cardiovascular disease in patients with microalbuminuria (MA) is unknown.
Currie, Gemma E.   +11 more
core   +3 more sources

"ON CYCLIC (OR PHYSIOLOGICAL) ALBUMINURIA." [PDF]

open access: yesThe Lancet, 1888
n ...
Ralfe, CharlesH, Barnes, Robert
openaire   +2 more sources

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