Determination of Albuminuria as a Component of Screening for Type 2 Diabetes Mellitus
Objective of the Study. Determining the prevalence of albuminuria in patients with diagnosed diabetes mellitus type 2 (DM2). Materials and Methods of the Study.
L.O. Prystupiuk
doaj +1 more source
Randomized multicentre pilot study of sacubitril/valsartan versus irbesartan in patients with chronic kidney disease: United Kingdom Heart and Renal Protection (HARP)- III—rationale, trial design and baseline data [PDF]
BACKGROUND: Patients with chronic kidney disease (CKD) are at risk of progression to end-stage renal disease and cardiovascular disease. Data from other populations and animal experiments suggest that neprilysin inhibition (which augments the ...
Baigent, C. +23 more
core +1 more source
Urinary peptide-based classifier CKD273: towards clinical application in chronic kidney disease [PDF]
Capillary electrophoresis coupled with mass spectrometry (CE-MS) has been used as a platform for discovery and validation of urinary peptides associated with chronic kidney disease (CKD).
Mischak, Harald, Pontillo, Claudia
core +1 more source
Background Gout arthritis associates with many comorbodities such as hyperuricemia, hypertension, hyperglycemia, obesity, and dyslipidemia, which are also factors for the development of/or predisposition factors of chronic kidney diseases (CKD ...
Jeffrey Christian Mahardhika +1 more
doaj +1 more source
Prevalence and Determinants of Diabetic Nephropathy in Korea: Korea National Health and Nutrition Examination Survey [PDF]
BackgroundDiabetic nephropathy is a leading cause of end stage renal disease and is associated with an increased risk of cardiovascular mortality. It manifests as albuminuria or impaired glomerular filtration rate (GFR), and the prevalence of diabetic ...
Jae Hee Ahn +14 more
doaj +1 more source
Long-term glycemic variability and risk of adverse outcomes: a systematic review and meta-analysis [PDF]
OBJECTIVE: Glycemic variability is emerging as a measure of glycemic control, which may be a reliable predictor of complications. This systematic review and meta-analysis evaluates the association between HbA1c variability and micro- and macrovascular ...
Catherine Gorst +18 more
core +1 more source
Progression of albuminuria in patients with sickle cell anemia: a multicenter, longitudinal study.
Sickle cell nephropathy results in chronic kidney disease (CKD), which is associated with significant morbidity and mortality in sickle cell anemia (SCA).
O. Niss +11 more
semanticscholar +1 more source
The impact of nonalcoholic fatty liver disease on renal function in children with overweight/obesity [PDF]
The association between nonalcoholic fatty liver disease (NAFLD) and chronic kidney disease has attracted interest and attention over recent years. However, no data are available in children.
Andreoli, Gian Marco +6 more
core +6 more sources
The Potential of Albuminuria as a Biomarker of Diabetic Complications
Diabetes mellitus is a disease of dysregulated blood glucose homeostasis. The current pandemic of diabetes is a significant driver of patient morbidity and mortality, as well as a major challenge to healthcare systems worldwide.
Pappitha Raja, A. Maxwell, D. Brazil
semanticscholar +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source

